Our labs @HelmholtzMunich and @TU_Muenchen are interested in how metabolic rewiring impacts #ferroptosis and how this can be harnessed for #drugdesign

Munich, Bavaria
Joined June 2019
The Conrad Lab retweeted
A cholesterol metabolite against ferroptosis | Nature Cancer nature.com/articles/s43018-0…
5
22
1,607
What an awesome @MolecularCell cover! Check out the PRDX-6 license plate on the truck carrier — #ferroptosis on the move. Well done, @Conrad_Lab and @AngeliFriedmann. @eikan_em @Ferroptosis1 @Ferroptosis2306 @KojinTx #selenium #biotech
Thrilled that our design made the cover of the current @MolecularCell issue! Congratulations again to the team @eikan_em and Junya as well as the companion paper by @AngeliFriedmann group!
2
15
1,824
The Conrad Lab retweeted
Thrilled that our design made the cover of the current @MolecularCell issue! Congratulations again to the team @eikan_em and Junya as well as the companion paper by @AngeliFriedmann group!
1
5
2
48
6,143
The Conrad Lab retweeted
It’s an honor to see that we made it to this list again! #ferroptosis research is thriving! Also, congratulations to all colleagues and collaborators, including @SJD956, @AngeliFriedmann, @Linkermann_Lab, @bstockwell, and many others!
IT’S HERE! The Highly Cited Researchers 2024 list has now been published. #HighlyCited2024 Discover the world’s influential #researchers: clarivate.com/news/clarivate…
2
3
1
29
7,631
The Conrad Lab retweeted
Very pleased to be listed as a highly cited researcher — a testament to a great network of trainees and collaborators and the ever-growing #ferroptosis community! clarivate.com/highly-cited-r…
It’s an honor to see that we made it to this list again! #ferroptosis research is thriving! Also, congratulations to all colleagues and collaborators, including @SJD956, @AngeliFriedmann, @Linkermann_Lab, @bstockwell, and many others!
1
2
37
5,097
Congratulations to the leaders of #ferroptosis research for recognition of their work by the scientific community. @Conrad_Lab @bstockwell @SJD956 @AngeliFriedmann @Linkermann_Lab Therapeutic translation in #cancer and #immune diseases on the horizon.
2
1
7
545
Congratulations @Conrad_Lab !
Congrats to our Award-Winning Ferroptosis Expert 🎉 👉 Read about the recent achievements of Prof. Marcus Conrad in our news: t1p.de/1otrz Marcus Conrad is an expert in #ferroptosis. He received the Galenus Award for his ferroptosis research and has been honored with the ECDO Honorary Award 2024 for his pioneering work on cell death mechanisms and cancer therapy. Now appointed as Professor of Translational Redox Biology at the @TU_Muenchen, he leads the way in merging research and clinical advances. @Conrad_Lab #HelmholtzMunich #CellDeath #Cancer #Therapy #Research
2
25
1,046
Replying to @Conrad_Lab
@Conrad_Lab of @HelmholtzMunich is leading our growing understanding of the role of #ferroptosis in human disease, especially #cancer and #neurodegenerative diseases. Recent studies on selenium carrier protein, PRDX-6, from the lab highlight new therapeutic opportunities.
For everyone interested in our science! Our Institute was recently featured by our center @HelmholtzMunich, giving a high-level summary of our work on #ferroptosis
1
2
10
866
Congrats to our Award-Winning Ferroptosis Expert 🎉 👉 Read about the recent achievements of Prof. Marcus Conrad in our news: t1p.de/1otrz Marcus Conrad is an expert in #ferroptosis. He received the Galenus Award for his ferroptosis research and has been honored with the ECDO Honorary Award 2024 for his pioneering work on cell death mechanisms and cancer therapy. Now appointed as Professor of Translational Redox Biology at the @TU_Muenchen, he leads the way in merging research and clinical advances. @Conrad_Lab #HelmholtzMunich #CellDeath #Cancer #Therapy #Research
3
2
30
5,776
The newly founded study group on Cellular Organelles of the German Society for Biochemistry and Molecular Biology @GBM_eV had its first symposium in Kaiserslautern. Exciting meeting with excellent talks and posters! So much fun! Next year, we organelle lovers meet in Düsseldorf!
3
6
4
64
8,498
Online Now: PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization dlvr.it/TGBDvX
25
1
126
14,723
Online Now: PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance dlvr.it/TGB651
8
1
59
6,307
The Conrad Lab retweeted
Check out our latest work, hot off the press @MolecularCell
Novel Selenium Carrier Protein Regulates Ferroptosis in Cancer and Brain🧫 👉Read more: t1p.de/kr969 Scientists at #HelmholtzMunich have uncovered the selenium carrier protein PRDX6 as a critical player in #ferroptosis - a cell death process that holds promise for #cancer and neurodegenerative disease #therapies. 💡This study reveals PRDX6’s dual role as both a regulator of #OxidativeStress and a selenium transporter, essential for maintaining cellular defenses against damage. 🌟Implications: Targeting PRDX6 may increase sensitivity to ferroptosis in cancer cells, a potential new strategy against therapy-resistant #tumors. In neurodegenerative diseases like #Alzheimer’s, PRDX6 could help protect neurons by supporting selenoprotein production, opening doors for therapeutic advancements. @Conrad_Lab @Ferroptosis2306 @Ferroptosis1 #CancerResearch #NeurodegenerativeDisease #Selenium #MultipleSclerosis
6
30
2,408
The Conrad Lab retweeted
Obviously, this work would not have been possible without the continued generous support to the @Conrad_Lab by @HelmholtzMunich @dfg_public @ERC_Research and @Ferroptosis2306. THANK YOU!
1
2
4
573
The Conrad Lab retweeted
But also Deng, Carsten, Gereon, Andre, Sebastian, Mirai Suzuki, Weijia, Jiashuo, Dietrich, Naoya, Koya, Masana Yazaki, Yasutaka Kawai, Mieko Arisawa, Yusuke Ohsaki, Hitoshi Shirakawa, Yoshiro Saito, and Kiyotaka Nakagawa !
1
1
2
526
The Conrad Lab retweeted
At this point, I would like to express my gratitude to all members of my group and the collaborators who made this work possible. @ToshiNakamura51 @BettinaProneth @damwahida and Takashi Toyama
1
1
1
291
The Conrad Lab retweeted
Importantly, our work was published along with a companion paper by @AngeliFriedmann, underscoring a long-standing and cherished collaboration!
1
1
6
286