Comanche Biopharma

Yesterday, @WHO and its partners announced a new global roadmap to tackle hypertensive disorders of #pregnancy, including #preeclampsia. Comanche is honored to have participated as part of the global consortium of health authorities, researchers, clinicians, patient advocacy groups, and industry that created this critical roadmap. It sets the much-needed, global agenda for developing novel treatments, preventions, and diagnostic and process of care improvements worldwide. Together, let's make pregnancy safer for moms and babies globally! Learn more: who.int/news/item/08-10-2026… Thanks to @WHO, @gatesfoundation, #MerckforMothers, and @UNITAID for their leadership!

Happy Father’s Day!  Today, we want to particularly acknowledge preeclampsia’s underappreciated impact on fathers. Preeclampsia and other pregnancy complications can mean watching someone you love face the unexpected while trying to be her calm, her advocate, and her source of strength. To these dads, and to all dads, we see and celebrate you! #Preeclampsia #FathersDay

The first-ever @WHO /HRP Global #Preeclampsia Summit just took place in Kigali. Comanche was there. 150+ stakeholders. 50+ countries. United around the urgent need to prevent, diagnose, and treat preeclampsia at a global scale. The hard work of turning that commitment into action starts now. #pregnancy #maternalhealth #obstetrics #pregnancy

Prof. Shaun Brennecke AO has spent decades advancing preeclampsia research, authoring 450+ publications, co-founding Australia's only preeclampsia patient organization AAPEC in 1993, and is now Principal Investigator for Comanche's Phase Ib trial of CBP-4888. Honored to work alongside him.

Preeclampsia is one of the leading causes of maternal and infant mortality worldwide. It affects between 2% and 8% of all pregnancies and is linked to more than 70,000 maternal deaths and approximately 500,000 perinatal deaths each year. This month, for Preeclampsia Awareness Month, Comanche Biopharma is proud to join the global community of researchers, clinicians, and patient advocates working to end #preeclampsia. While significant progress has been made in understanding and diagnosing this disease, no approved treatment yet exists. Comanche is working to change that, developing the first ever therapy targeting a root cause of preeclampsia. Throughout May, we are highlighting the global impact of this disease and the extraordinary people dedicating their careers to addressing it. #maternalhealth #EndMaternalMortality #pregnancy #obstetrics #precisionmedicine

Held annually on April 11-17, Black Maternal Health Week (BMHW) is a week-long campaign founded and led by the Black Mamas Matter Alliance, Inc. (BMMA) to build awareness, foster activism, and community-building, amplifying the voices, perspectives, and lived experiences of Black mamas and birthing people. Black women have the highest prevalence of #preeclampsia and #eclampsia, experiencing these disorders at rates five times higher than their white counterparts. This BMWH, we help raise awarness of this and other maternal health disparities impacting Black mothers, and the need to address the multifactorial inequalities driving these stark gaps. Learn more @ blackmamasmatter.org/. #BMHW26 #BlackMamasMatter #ENDMaternalMortality

We're thrilled to announce the appointments of Richard Colvin, MD, PhD, as Global Head of Research and Development, and John McHutchison, AO, MD as Chairman and Director of Comanche Biopharma Australia. Rich and John's deep expertise and leadership will help further Comanche’s commitment to deliver CBP-4888 as a global solution for sFlt1-mediated preterm preeclampsia, a serious, life-threatening obstetric complication that impacts women and babies around the world. Read press release: bit.ly/49RHsg6

Congratulations to @allysonfelix on her induction into the U.S. Olympic & Paralympic Hall of Fame Class of 2025! Allyson is the most decorated track and field athlete in Olympic and World Championship history, with 11 Olympic medals and 31 total medals across global competitions. Her induction recognizes a historic athletic career defined by excellence, determination, and global impact. As a member of Comanche Biopharma’s Board of Directors, Allyson brings the same clarity and commitment that defined her track and field career to our shared mission of making pregnancy safer around the world. #AllysonFelix #TeamUSA #OlympicLegend #MaternalHealth #ComancheBiopharma

As Preeclampsia Awareness Month comes to a close, we extend our gratitude to all the Champions of Change who shared their experiences. From personal stories of survival and healing to the groundbreaking work of advocates and scientists, each contribution brought to light the realities of preeclampsia, eclampsia, and HELLP syndrome, and the strength, dedication, and vision it takes to confront them. Thank you for inspiring greater understanding, deeper empathy, and a continued commitment to progress. Comanche Biopharma is dedicated to driving meaningful change in maternal health. We are guided by purpose, grounded in evidence, and committed to those we serve. We hope you’ll follow our journey. comanchebiopharma.com/

On World Preeclampsia Day, we recognize the scientists, clinicians, and advocates working to change the future of maternal health. Science transforms lives, and Dr. Ananth Karumanchi’s discoveries have transformed our understanding of preeclampsia. By identifying sFlt-1 as a root cause, his work enabled the development of diagnostic tools now used around the world and continues to guide efforts to develop effective treatments. We are especially grateful for his insight in shaping our clinical program and for the enduring impact he has made on maternal health.

On Thursday, May 22 at 12:00 PM ET, @EndPreeclampsia is hosting an important World Preeclampsia Day program: The Preeclampsia Puzzle: Biomarkers and Breakthroughs. This session will explore how science is helping to piece together the causes of preeclampsia, how it can be detected earlier, and how clinical research is shaping the future of care. Featuring Maged Costantine and Michelle Silasi, and moderated by EndPreeclampsia founder Kara Boeldt, the program will make complex science more understandable and more meaningful for everyone. Registration is now open: us02web.zoom.us/webinar/regi… #WorldPreeclampsiaDay #PreeclampsiaAwareness #EndPreeclampsia

Jennifer is one of Comanche’s trusted patient advisors and a survivor of eclampsia, HELLP syndrome, and sepsis. What began as a normal day ended in an emergency delivery, days in the ICU, and a month-long NICU stay for her son Donovan. The experience shaped her decision to focus on advocacy and public health. We’re honored to feature Jennifer’s story as part of our Champions of Change series during Preeclampsia Awareness Month. Read Jennifer's story here: comanchebiopharma.com/champi… #PreeclampsiaAwarenessMonth #ChampionsOfChange #Preeclampsia #HELLPsyndrome #Pregnancy

@Eleni_Z_Tsigas has turned personal loss into lasting change for countless families worldwide. Her leadership of the @Preeclampsia Foundation has changed the landscape of maternal health advocacy. We are grateful for her strength, vision, and relentless push to improve outcomes for moms and babies everywhere. #ChampionsOfChange #PreeclampsiaAwarenessMonth #PreeclampsiaFoundation #PreAM25 #Preeclampsia

This Mother’s Day, we invite you to read a reflection from Valerie Thomas, a Comanche Biopharma co-founder and Head of Patient Advocacy. Valerie shares her personal story of surviving preeclampsia and how that experience continues to drive her commitment to advancing maternal health. Her journey is a reminder of what’s at stake and why meaningful progress in pregnancy care is so urgently needed. Read Valerie's reflection here: comanchebiopharma.com/why-i-… #PreeclampsiaAwarenessMonth #ChampionsOfChange #Preeclampsia #HELLPsyndrome #Pregnancy #MothersDay

For 25 years, the @Preeclampsia Foundation has advanced education, advocacy, and support for families affected by preeclampsia. We celebrate their incredible work and thank them for their pioneering leadership and dedication. And we look forward to the next 25 years of progress together! #PreeclampsiaAwarenessMonth #PreAM25 #PreeclampsiaFoundation #Preeclampsia

We are honored to launch this year’s Champions of Change series with Kalah’s story. Her experience with preeclampsia and HELLP reminds us why we must keep pushing for better care in pregnancy. Read Kalah's story here: comanchebiopharma.com/champi… #PreeclampsiaAwarenessMonth #ChampionsOfChange #Preeclampsia #HELLPsyndrome #Pregnancy

This Preeclampsia Awareness Month, we honor our Patient Advisors whose voices drive us to listen with greater care and innovate with purpose. We'll share their powerful stories and celebrate these champions advancing hope and change for moms and babies. #ChampionsOfChange #PreeclampsiaAwarenessMonth