The Lab for NeuroImaging of Coma and Consciousness is dedicated to promoting recovery from severe brain injury.
Massachusetts General Hospital
Joined March 2016
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We are proud to release a 100 micron MRI scan of the human brain. Preprint on biorxiv.org/cgi/content/shor…. Videos on youtube.com/playlist?list=PL…. Dataset will be available in native space and MNI space at datadryad.org and integrated into lead-dbs.org. [1/2]
Brian Edlow retweeted
[3/4] As a proof-of-concept test of clinical relevance, patients' subnetwork patterns in the brainstem correlated with their level of consciousness after severe traumatic brain injury. Early signal, more validation needed, but a promising direction for precision neuromodulation.
Brian Edlow retweeted
[2/4] Using resting state fMRI from 1,000 healthy adults (Human Connectome Project), we identified 15 reproducible subnetworks across 4 major systems (default mode, sensorimotor, visual, higher-order cognitive), spanning cortex and subcortex together.
Brian Edlow retweeted
[1/4] We mapped and fractionated large-scale brain networks in the human subcortex using NASCAR, a method built to untangle overlapping, correlated brain networks, recovering structure that conventional methods can't resolve.
Paper: doi.org/10.1073/pnas.2608875…
Brian Edlow retweeted
1/ 🚨 Just out in @NatureNeuro! 🧠
We profiled >6,000 features of brain dynamics across humans + monkeys, mice, fish and worms 🧑🐒🐒🐁🐟🪱 to find a shared neural endpoint of anaesthesia: spatiotemporal isolation of local activity 🧵
🔗 doi.org/10.1038/s41593-026-0…
Brian Edlow retweeted
Learn more about Cognitive Motor Dissociation & Covert Consciousness: A Roadmap to Diagnosis and Treatment, a two-day hybrid symposium taking place October 5-6, bringing together researchers, clinicians, advocates, ethicists, and industry partners to explore advances in diagnosis, treatment, and future research priorities for patients with disorders of consciousness. Register to attend today: mregs.nih.gov/ninds/5lcl-5z4…
Brian Edlow retweeted
Last week, @MassGenBrigham & Home Base celebrated the Thomas C. Werner Endowed Chair for Military Health, which honored inaugural incumbent Kaloyan Tanev, MD, MPH.
This incredible milestone marks the first-ever endowed chair in Home Base history.
📰: homebase.org/press-tanev-wer…
Brian Edlow retweeted
A message from Home Base.
Please reach out to us for support at homebase.org/getcare.
Brian Edlow retweeted
Are you a patient, family or caregiver who has lived through or cared for a patient in coma or a disorder of consciousness? The Curing Coma® Patient & Family Advisory Council is recruiting advisors to help shape research, education, and policy. Details: curingcoma.org/Get-Involved/…
🤖 Made with AI
Brian Edlow retweeted
Blast wave brain injuries don't show up on a scan. No easy diagnostic test exists yet, so symptoms often get mistaken for PTSD.
Dr. James Kelly (our Chief Medical Scientist, founding director of NICoE): "We're getting there, but it's imperfect."
550,000+ TBIs diagnosed since 2001. We think the real number is 3-4x that.
reservenationalguard.com/res…
#InvisibleWoundsFoundation #TBI
Brian Edlow retweeted
On August 6, 2026, we mark 15 years since the tragic loss of Extortion 17. On this day in 2011, 30 American servicemen and a U.S. military dog lost their lives when a CH-47 Chinook helicopter—call sign Extortion 17—was shot down in Afghanistan. This event remains the greatest single loss of life for Naval Special Warfare.
Please take a moment and pause to honor and remember these heroes and their families.
Chief Special Warfare Operator (SEAL) Aaron C. Vaughn
Chief Special Warfare Operator (SEAL) Brian R. Bill
Chief Special Warfare Operator (SEAL) Christopher G. Campbell
Chief Special Warfare Operator (SEAL) Darrik C. Benson
Senior Chief Special Warfare Operator (SEAL) Heath M. Robinson
Information Systems Technician 1st Class (TECH) Jared W. Day
Chief Special Warfare Operator (SEAL) Jason R. Workman
Special Warfare Operator 1st Class (SEAL) Jesse D. Pittman
Master At Arms 1st Class (TECH) John Douangdara
Chief Special Warfare Operator (SEAL) John W. Faas
Chief Special Warfare Operator (SEAL) Jon T. Tumilson
Lieutenant Commander (SEAL) Jonas B. Kelsall
Chief Special Warfare Operator (SEAL) Kevin A. Houston
Senior Chief Explosive Ordnance Disposal Technician (EOD) Kraig M. K. Vickers
Master Chief Special Warfare Operator (SEAL) Louis J. Langlais
Chief Special Warfare Operator (SEAL) Matthew D. Mason
Cryptologic Technician Collections 1st Class (TECH) Michael J. Strange
Chief Explosive Ordnance Disposal Technician (EOD) Nicholas H. Null
Special Warfare Operator 2nd Class (SEAL) Nicholas P. Spehar
Chief Special Warfare Operator (SEAL) Robert J. Reeves
Chief Special Warfare Operator (SEAL) Stephen M. Mills
Senior Chief Special Warfare Operator (SEAL) Thomas A. Ratzlaff
Brian Edlow retweeted
On July 25th, nearly 3,400 runners & walkers participated in #RTHB2026 at Fenway Park & virtually around the country, helping to raise over $4 million in support of our program.
Both numbers are record highs. ❤️
See our sights & sounds recap at homebase.org/rthb2026-sands.
Brian Edlow retweeted
The big advance in the science of human aging is the ability to quantify it and relate the metrics to health and disease. A new paper today @CellCellPress takes this to the next level with organ clocks and multiple biologic layers (omics) of data across the lifespan.
cell.com/cell/fulltext/S0092…
Two new tools to map the human brainstem:
nuclei: onlinelibrary.wiley.com/doi/…
bundles: pnas.org/doi/10.1073/pnas.25…
code: surfer.nmr.mgh.harvard.edu/f…
github.com/markolchanyi/BSBT
@olchanyi @JuanEugenioIgl1 @MGHMartinos @MGH_CNTR @MGBResearchNews @MIT
Grateful for support from:
@ChenInstitute @JSMF @RappFoundation @NINDSfunding @DeptofWar @NIBIBgov @NIMHDirector @ABFbrain @HumanConnectome
Brian Edlow retweeted
World Coma Day is a free, global event raising awareness about coma and disorders of consciousness. Register today to join providers, patients, families, and advocates from around the world for a 24-hour program of stories, science and hope on March 22. bit.ly/4mLEPip
A new atlas for MRI segmentation with unprecedented anatomic detail, based on probabilistic histology.
Congratulations @JuanEugenioIgl1 and team @MGHMartinos!
nature.com/articles/s41586-0…
Brian Edlow retweeted
Main project website: github-pages.ucl.ac.uk/NextB…
Open access paper: nature.com/articles/s41586-0…
Segmentation tool on @FreeSurferMRI: surfer.nmr.mgh.harvard.edu/f…
Data: doi.org/10.5522/04/24243835
Source (registration): github.com/acasamitjana/ERC_…
Source (segmentation) github.com/freesurfer/freesu…
(2/3)
Brian Edlow retweeted
Ten years (!) after submitting the grant, NextBrain is published in @Nature . NextBrain is a brain atlas built from 3D histology that enables segmentation of 3D brain scans (MRI, Hip-CT, even photos!) into hundreds of regions.
Article, data, code, videos, & more in this 🧵 (1/3)
Congratulations to @bu_cte @BU_Tweets @VABostonHC on this landmark contribution to the field of chronic traumatic encephalopathy (CTE):
nature.com/articles/s41586-0…
Elegant and groundbreaking work, with substantial public health implications.
Brian Edlow retweeted
Mark your calendar and register for free for World Coma Day! This all-day, global online event will feature stories of remarkable recovery, science talks by medical experts, educational sessions & more. bit.ly/4gHAvOb #awakeninghope #WorldComaDay
@CuringComa
