Find me now on BlueSky: https://xitter.cf/t.co/aggHsWYe3g Postdoctoral scientist - ZMBP, University of Tübingen Plant-Microbe Interactions (she/her)
Tübingen, Deutschland
Joined March 2015
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Check out the final version of our #Pikobodies story as first seen on @biorxiv ! One step further to building made-to-order resistance genes in plants! @JiorgosKourelis @adnroide @Adeline_Harant @KamounLab @TheSainsburyLab
science.org/doi/10.1126/scie…
Clémence Marchal retweeted
I just published: On the diversity of resting states of NLR immune receptors
New story on the rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!
medium.com/p/on-the-diversit…
Clémence Marchal retweeted
The Pik NLR pair does more than just wait for activation!
Adding to the known modes of action for NLR proteins: from monomer/dimer to a novel pre-activation heterocomplex 🤜🤛
Get the full mechanism in our new preprint!
Check out our new story on the famous rice Pik NLR pair, led by @ClemMarchal and @HsuanPai1 ! Turns out they form a massive 1 MDa membrane-associated complex before activation 🤯 A cool new example of the diversity of NLR resting states!
Clémence Marchal retweeted
A plant pathogen effector blocks stepwise assembly of a helper NLR resistosome biorxiv.org/content/10.1101/… #biorxiv_plants
Clémence Marchal retweeted
Happy to share our latest discovery of the autoactive CNGC15, sufficient to enhance root endosymbiosis in legume and field grown wheat: nature.com/articles/s41586-0…
Thank you to everyone involved! Special shout-out @NicMCook1, G.Gobbato, collaborators
@DaveLawson101 , @CristobalUauy
Clémence Marchal retweeted
I am super excited to share our latest preprint on novel agrobacterial strains enabling hyper-efficient transient expression in N. benthamiana and other solanaceous plants! This work is a collaborative effort between my lab, @erhminlai, and @ChihHorngKuo!
biorxiv.org/content/10.1101/…
Clémence Marchal retweeted
The artist @HsuanPai1 encounters her art in the wild at @BS_PP! Worn by the legend @McdonaldMeganc on top of it 🤯
Clémence Marchal retweeted
The final version of our Fusarium review is now online! First time contributing to composite review figures—huge thanks to @RedkarAmey and all the co-authors for this opportunity! Also big thanks to the AR illustration team for polishing our submission 😊 annualreviews.org/content/jo…
Clémence Marchal retweeted
Today I presented my talk and poster at #NoCaSS2024. It’s a short summary on AIMapper, the automated pipeline we have been building together with @TarhanEI to streamline the screening for AIMs in pathogen proteomes. You can find the poster on Zenodo! zenodo.org/records/13709932
Clémence Marchal retweeted
I feel excited and honoured that @ERC_Research selected my project for funding! 🎉
With our #ERCStG "FRIENEMIES" we will investigate the #evolution of plant-fungus interactions from pathogenic to beneficial in land plants @ZMBP_Tuebingen @uni_tue
#EvoMPMI #PlantSci
📣 The latest ERC Starting Grant competition results are out! 📣
494 bright minds awarded €780 million to fund research ideas at the frontiers of science.
Find out who, where & why 👉 europa.eu/!hrxyBp
🇪🇺 #EUfunded #FrontierResearch #ERCStG @HorizonEU @EUScienceInnov
Clémence Marchal retweeted
How can protein complexes diversify without compromising their function? In our new pre-print, we explore this question using the plant #exocyst 🧵
biorxiv.org/content/10.1101/…
Clémence Marchal retweeted
Out now from the Open Wild Wheat Consortium: ‘Origin and evolution of the bread wheat D genome’. 46 Tauschii genomes shed new light on the bread wheat D genome history. Almost 40% of the D genome gene content resulted from secondary hybridization events.
nature.com/articles/s41586-0…
Clémence Marchal retweeted
A tightly regulated copper-inducible gene expression system in Nicotiana benthamiana
Chiang et al. @AdamWu9527 @IPMBSinica
📖 ow.ly/wLNY50SOkXu
ALT Copper-inducible system stands out as an optimal choice for regulating gene expression in Nicotiana benthamiana.
Clémence Marchal retweeted
Very excited to share our latest paper! We solved the structure of the helper NLR NRC2 activated by the virus resistance protein Rx using cryo-EM. It forms a hexameric inflammasome-like resistosome!
1/14
biorxiv.org/content/10.1101/…
Clémence Marchal retweeted
I am thrilled to share our story of paired NLRs behind Yr84-mediated resistance in wheat. Many of you heard some pieces from my oral talks at the conferences, but finally we are ready to present it in a manuscript! @CurtisPozniak
biorxiv.org/content/10.1101/…
Clémence Marchal retweeted
Very excited to share our latest preprint about coevolutionary dynamics between NLRs and their inhibitor!
Solanaceae helper NLR NRC3 evolved to evade the inhibition by cyst nematode effector SS15 over 19 Mya (1/12) #EvoMPMI #NLRbiology #PlantPath #PlantSci
doi.org/10.1101/2024.06.16.5…
Clémence Marchal retweeted
Last call 📢 There is still some time left (deadline 17.06) to apply for the #PhD position in #theustunlab. More info below in the post or here: theustunlab.com/positions/
📢 We have an open #PhD position available to study "Processing bodies as a target of pathogenic bacteria". If you're interested in #proteostasis, processing bodies, plant-microbe interactions apply ♻️🌱🦠🔬 Please share 📢 More info in the ad and here theustunlab.com
Clémence Marchal retweeted
1,5 month left to apply. Reviewing & interviews to start August 🌱⏱️ Please share!
We are looking for a postdoctoral researcher to join our lab @ZMBP_Tuebingen . If you're interested in plant development and cell fate regulation please apply!
Please RT 📢
Check out our website for info about our research 🌱⏱️: tinyurl.com/fkf2wukn
ALT Job ad text, truncated: Postdoc position (m/f/d, E 13 TV-L, 100%) in the Timing of Fate Transitions Lab A Postdoc position (initially 2 years) is available in our laboratory in the Center for Plant Molecular Biology (ZMBP), at the University of Tübingen (Germany). The position is available with an intended start date starting February 2025. Your profile We are looking for a curiosity-driven, highly motivated candidate with good communication and teamwork skills who can work independently in a goal-oriented manner. The candidate should have a PhD in Plant Biology, preferentially with a focus on Developmental Biology or Bioinformatics. Excellent English written and oral skills are required, previous experience with Arabidopsis thaliana, confocal imaging, and single cell approaches are a plus. For the full ad see our website https://tinyurl.com/fkf2wukn
Clémence Marchal retweeted
Together with my colleague @jrufian86 as guest editors at @JoVEJournal, we are pleased to invite contributions to the newly released methods collection dedicated to pioneering methods in plant-microbe interactions. For more info ▶️ app.jove.com/methods-collect…
Clémence Marchal retweeted
📄 New Publication: The nucleotide-binding domain of NRC-dependent disease resistance proteins is sufficient to activate downstream helper NLR oligomerization and immune signaling @mpcontreras4 @HsuanPai1 @KamounLab @ClemMarchal @HiroakiAdachi3
tsl.ac.uk/publications/12693…
Clémence Marchal retweeted
Very happy to see the peer-reviewed version of our recent preprint online on @NewPhyt ! We found that the nucleotide binding domain of sensor NLRs is sufficient to activate downstream NRC helpers!
nph.onlinelibrary.wiley.com/…
