
I love sharing what I learn every day. ICU doctor, teacher, investigator. Passionate about #criticalcare, #resuscitation, #emergencymedicine, #cardiacarrest.
UCSC University Rome, IT
Joined March 2022
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We found that organs transplanted after CPR have comparable outcomes than organs from donors who did not receive CPR. Kidneys and livers donated from brain-dead donors following CPR had better outcomes than those from uncontrolled DCD.
authors.elsevier.com/c/1lA9D…~
In post-cardiac arrest #coma, the ERC-ESICM 2021 algorithm is 100% specific for poor outcome prediction, and in patients with indeterminate outcome, favourable signs predict recovery with 99% specificity! Online on Resuscitation pubmed.ncbi.nlm.nih.gov/3915…
In patients with acute myocardial infarction and preserved (>49%) ejection fraction who underwent early coronary angiography, beta-blockers do not improve survival or decrease the rate of new infarction. Today on NEJM:
nejm.org/doi/full/10.1056/NE…
This is an excellent case discussion for those - like me - who are passionate of #cardiacarrest and #resuscitation:
A 55-Year-Old Man with Cardiac Arrest, Cardiogenic Shock, and Hypoxemia | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…
During #sleep, the synchronous neuronal electrical activity produces rhythmic waves that flush CSF washing out waste. Stopping these waves leads to waste accumulation. Are we close to understanding why we sleep and why sleep deprivation is harmful?
nature.com/articles/s41586-0…
Claudio Sandroni retweeted
In a retrospective observational study, up to 25% of patients admitted to the ICU with presumed #sepsis had noninfectious diagnoses (i.e., sepsis mimics). jwat.ch/3TshcQx
#MedTwitter
In adult patients undergoing emergent or elective surgery Glidescope laryngoscopy is associated with fewer intubation attempts and fewer intubation failures (0.3 vs 4.0%) than direct laryngoscopy with McIntosh blade. Today on JAMA
jamanetwork.com/journals/jam…
Claudio Sandroni retweeted
Neurological conditions now leading cause of ill health and disability globally, affecting 3.4 billion people worldwide, suggests GBD study in @TheLancetNeuro
🔗 buff.ly/43kfZyo
Claudio Sandroni retweeted
Adolf Hitler was “a good patient,” according to his doctors. He was meticulously adherent to the regimen for his chronic sinusitis: cocaine in aerosol form.
Hitler’s drug use was of epic proportions. In addition to cocaine, the German Fuhrer also took amphetamines, sedatives, and hormones.
In his book Blitzed, German author Norman Ohler describes how the Third Reich was permeated with drugs, including cocaine, heroin and most notably crystal meth, which was used by everyone from soldiers to housewives and factory workers.
Ohler also says that Hitler, whose mental and physical health has been the source of much speculation, relied on daily injections of the “wonder drug” Eukodol, which puts the user in a state of euphoria – and often renders them incapable of making sound judgments.
In a meta-analysis of 32 582 patients from 89 studies, females were significantly more at risk of dying from S. Aureus bacteraemia than males (pooled adjusted OR, 1.18; 95% CI, 1.11-1.27).
jamanetwork.com/journals/jam…
Claudio Sandroni retweeted
Therapeutic antibiotic concentrations in children & adults with #sepsis in #ICU
⏱️Bayesian dosing software reduced time to achieve target ABT exposures in those who failed to achieve target exposure in first 24h
🪦no difference in in-hospital mortality
🔓rdcu.be/dBidE
14 Recommendations on the use of intravenous albumin, from the International Collaboration for Transfusion Medicine Guidelines. Pre-proof available on the Chest website. sciencedirect.com/science/ar…
Claudio Sandroni retweeted
Hematologic malignancies in 7 🇨🇦 ICUs
🔍most common reasons for admission ARF/#sepsis
🔍improved, but still high #ICU/post ICU mortality
🔍survival varied based upon diagnosis & frailty status
🔍functional disability & impairment in well-being reported
🔓 rdcu.be/dAZPT
Claudio Sandroni retweeted
Managing acute mesenteric ischaemia, review summarizing recent evidence related to:
⏱️ (timely) diagnosis
⚙️ (multidisciplinary) management
⚖️ outcome
Awareness, allowing adequately raised/shared suspicion followed by early approach, pivotal!
#FOAMcc
🔓 bit.ly/3Pj6fOY
Impressive results from the KARDIA-1 RCT. In hypertensive adults, a single shot of the silencing RNA zilebesiran lowered SBP by 10 mmHg for 90 days.
Future effects if patients develop #hypovolaemia or #shock?🤔
jamanetwork.com/journals/jam…
The rate of immunosuppression in US adults is 6.6% (7.9% in women) in this survey. Sample >29,000. Response rate 53%. Limitations: self-reported; causes not investigated. Today on JAMA: jamanetwork.com/journals/jam…
In the ACORN randomised trial on 2511 adults with acute #infection in ED or ICU at enrollment, #Piperacillin_Tazobactam (bolus + ext. infusion) was not associated with higher AKI rates vs. Cefepime (10.2 vs. 8.8%).
jamanetwork.com/journals/jam…



















