Extreme enzymes for #proteomics and specialty applications. One-step/5-90 minute digests; Journal of Proteomics publication here (https://xitter.cf/t.co/dCEJPtuMqA)

Berkeley, CA
Joined November 2014
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Cinder Biological (@cinderbio.bsky.social) retweeted
News in Proteomics Research blog post | Near real-time plasma proteomics by LCMS! proteomicsnews.blogspot.com/… --- #proteomics #prot-other
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Team CinderBio with Simion Kreimer of the @1jvaneyk group (Cedars-Sinai) ready to present our collaborative work at #ASMS2024. Come see our breakthrough work on "Blood to Biomarkers in under one hour..." at Poster WP-189 Wednesday. #Proteomics #TeamMassSpec
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CinderBio will see you at #ASMS2024! See two posters (TP 342 & WP 189) with fascinating insight into the use of our alternative proteases, for #Proteomics. Use c-bio.link/6rmr88 to setup a meeting during ASMS. #TeamMassSpec #massspec
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Come check out poster 03.08 where @KreimerSimion presents rapid proteomics technology using @CinderBio proteases for acute-care clinical proteomics applications in 40 minutes or less. @us_hupo #ushupo2024
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@CinderBio will see you in Portland for US HUPO 2024! Please come chat with @yannone_steve (P1.37) and @KreimerSimion (P3.08) about the latest work with our enzymes Krakatoa & Vesuvius for #TeamMassSpec! See you soon... #proteomics #massspec
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We want to give a public "Thank You!” to early adopters of our initial HTA-Proteases. We're thrilled to contribute to knowledge in clinical proteomics, epigenetics, immunotherapies, cancer drug discovery and more. We enjoy being this kind of busy - Team CinderBio #proteomics
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Our founder, @yannone_steve, with @1jvaneyk at the first international single cell mass spectrometry conference held last week. Steve introduced attendees to our HTA-proteases (Krakatoa and Vesuvius). Some lucky folks took enzyme home with them (they’re backpack stable 😊)
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Cinder Biological (@cinderbio.bsky.social) retweeted
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Replying to @rbharathkumar91
@rbharathkumar91 We are working to further refine and optimize our protocols and search parameters and are open to input on how to do this in the most useful way.
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Answer to a question about an immobilized version of HTA-Proteases, suitability for HDX, and our interest in collaborations.
Replying to @ProteinMassSpec
There are plans for an immobilized product and our HTA-Proteases already work at lower temps, the rates are just slower. We are considering collaborative initiatives on these topics and more. If interested, please write to info at CinderBio.com.
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Replying to @ProteinMassSpec
There are plans for an immobilized product and our HTA-Proteases already work at lower temps, the rates are just slower. We are considering collaborative initiatives on these topics and more. If interested, please write to info at CinderBio.com.
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(2/2) Thank you to Max McCabe, @VarunGejji, Adam Barnebey, @kadzuis, Linh Truc Hoang, Truc Pham, Keira Larson, Anthony Saviola, Steve Yannone, and Kirk Hansen for all their efforts on the publication.
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(1/2) Introducing one-step/5 min. digests using new archaeal proteases for #proteomics. Generates #massspec data orthogonal to Trypsin, increasing peptide IDs and proteome coverage. Unique bias towards #membraneproteins. Read more in Journal of Proteomics; c-bio.link/PeoV3V
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