@ChauhanLab

The Chauhan lab is studying #Thromboinflammation #Stroke #Atherosclerosis and #VascularBiology @uiowa @IntMedatIowa

 Iowa City, IA
chauhan.lab.uiowa.edu
Joined October 2019
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Our new MRI-based study on venous thrombus resolution, published in RPTH (doi.org/10.1016/j.rpth.2025.…), was highlighted by Hemostasis Today (hemostasistoday.com/insight/…). We propose novel unified metrics to quantify thrombus resolution.
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Our review in Blood (doi.org/10.1182/blood.202402…) explores how targeting metabolic pathways opens new possibilities for safer DVT therapies. Honored to see it recognized by Prof. Flora Peyvandi in Hemostasis Today. hemostasistoday.com/science/…

Metabolic pathways in deep vein thrombosis: a new frontier for therapeutic intervention

There is increasing evidence that deep vein thrombosis (DVT) is an inflammation-driven process involving endothelial cells, neutrophils, and platelets. Met

ashpublications.org
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Delighted to share our latest article in @BloodAdvances demonstrating imbalanced VWF-ADAMTS13 axis worsen stroke outcomes following respiratory infection @RakeshPatel2083 @aditijain_5 @ironmonger012 @DrSaurabhSaini @joshuamuia @PrajwalGurung @Ivan19174090 ashpublications.org/bloodadv…
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Congratulations to Rakesh Patel, PhD, postdoc in @ChauhanLab, for his @AHA_Research fellowship. Dr. Patel will build on his work examining the connections between Von Willebrand Factor, respiratory tract infections, and stroke. internalmedicineiowa.org/202…

Patel receives AHA postdoc fellowship

Rakesh B. Patel, PhD, a postdoctoral research scholar in the lab of Anil Chauhan, MTech, PhD, received a two-year, $155,952 American Heart Association (AHA) Postdoctoral Fellowship for his project …

internalmedicineiowa.org
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A pair of University of Iowa researchers presented their research at the International Stroke Conference in Phoenix this week! They studied several potential cerebroprotective treatments and are using AI to help analyze data. #ISC24 #ISC24Midwest @IntMedatIowa @UIowaResearch
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The results of our collaborative study - Stroke Preclinical Assessment Network (SPAN1) are now out in @ScienceTM. A big kudos to our team @RakeshPatel2083 and @MKumskova, alongside Dr. Chauhan and @EnriqueLeira leading as PI's. science.org/doi/10.1126/scit…

A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic...

It is feasible to evaluate candidate treatments in a multi-laboratory preclinical network using utmost rigor and adaptive statistical methods.

science.org
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Delighted to share that our review article discussing the role of metabolic enzymes in regulating platelet function and thrombosis is now online on #CardiovascularResearch. @Gaganflora @manasbiotech @MadanGhatge @escardio @IntMedatIowa @CVR_TomaszGuzik academic.oup.com/cardiovascr…
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Thank you @ASHClinicalNews for featuring our paper in the Literature Scan of August issue - Bleeding Symptoms in Patients With #EhlersDanlosSyndrome Range From Mild to Life-Threatening ashpublications.org/ashclini… @ChauhanLab @janice_staber @IowaMSTP @Gaganflora
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#EhlersDanlosSyndrome patients are at high risk of #bleeding. Recent findings from our lab in @JTHjournal identify the severity and occurance of hemorrhage in EDS patients. @MKumskova @Gaganflora @janice_staber @IowaMSTP @ChauhanLab sciencedirect.com/science/ar…
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Happy to share the print version of our study demonstrating the role of MCUb in platelet activation and thrombosis is out in @JTHjournal. @MadanGhatge @manasbiotech @Gaganflora @MKumskova @Aditijain_5 @RakeshPatel2083 Zhihong Lin and Yuriy Usachev. sciencedirect.com/science/ar…
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Delighted to share the final version of our article on the role of neutrophil integrin α9β1 as thrombo-inflammation regulator after stroke in obese-hyperglycemic mice. @RakeshPatel2083 @Nirav_Dhanesha @MadanGhatge @prakashdp1 @MKumskova @EnriqueLeira ahajournals.org/doi/10.1161/….

Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced...

BACKGROUND: Obesity-induced hyperglycemia is a significant risk factor for stroke. Integrin α9β1 is expressed on neutrophils and stabilizes adhesion to the endothelium via ligands, including Fn-EDA...

ahajournals.org
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”The University of Iowa stands at the forefront of cerebrovascular research.” See how @uiowa researchers are working to advance stroke care by testing uric acid as a treatment method. spr.ly/6013OoJt3 #StrokeMonth
Anil Chauhan, PhD, and Enrique Leira, MD

ALT Anil Chauhan, PhD, and Enrique Leira, MD

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Excellent job by @MKumskova in presenting her findings on Ehlers-Danlos syndrome at #VascularDiscovery2023. Many congratulations to her on receiving a travel grant award for early career investigator. @IntMedatIowa @uiowa
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Excited to share that our latest research on the role of the pyruvate dehydrogenase kinases (PDK2 and PDK4) in #platelets is now out in @BloodAdvances. Huge thanks to everyone involved. @Gaganflora @manasbiotech @MadanGhatge @MKumskova @RakeshPatel2083 ashpublications.org/bloodadv…
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Congratulations to @uiowa - SPAN Team! @Nirav_Dhanesha @RakeshPatel2083 @MKumskova @EnriqueLeira @angelchamorro1 medcom.uiowa.edu/theloop/new…
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UI-led therapy is best for protecting brain tissue during stroke treatment medcom.uiowa.edu/theloop/new…
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Congratulations to @uiowa - SPAN Team! Final Result: Uric acid (16mg/kg) given intravenously at the time of reperfusion was found to be cerebroprotective in a multi-center pre clinical trial (SPAN) @Nirav_Dhanesha @RakeshPatel2083 @MKumskova @EnriqueLeira @angelchamorro1
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Great presentation by our postdoc @RakeshPatel2083 at #ISC23 to discuss the role of neutrophil-specific integrin alpha9 in improving stroke outcome in obesity induced hyperglycemic mice. @uiowa @IntMedatIowa
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Many congratulations to @manasbiotech on receiving a Travel Grant Award for Early career investigators at #AHA22 @atvbahajournals @American_Heart
Internal Medicine at Iowa@IntMedatIowa8 Nov 2022
Congratulations to @manasbiotech, Hem/Onc Research Assistant Professor, on his Travel Grant Award for Early Career Invesigators! #AHA22 @atvbahajournals @American_Heart
Dr. Manasa Nayak stands holding a certificate from the Council on ATVB indicating his recipt of a Travel Grant for Early Career Investigators

ALT Dr. Manasa Nayak stands holding a certificate from the Council on ATVB indicating his recipt of a Travel Grant for Early Career Investigators

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👉 #DHLRI looking forward to upcoming #PCB speaker Dr. Anil Chauhan, MTEch, PhD for his talk on "Pyruvare kinase M2: A novel target to combat thrombo-inflammation". DHLRI, Sept 21, 4pm DHLRI 170. #thrombosis #stroke #atherosclerosis @OhioStateMed @OSUWexMed
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