Mom 2 girl with #Pans.Took 2.5 years & huge battle 2 get 2 diagnosis!Delays are damaging. Goal 2 raise awareness 2 end present suffering & stop future suffering

Birmingham, England
Joined November 2016
As the parent,guardian,family member or friend of a child or adult with #pans #pandas I would like ......
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Thank you to each and everyone who advocates and shines a light for #Pans #Pandas #PansPandasAwarenessDay
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Joanne Holloway retweeted
panspandasuk.org/post/puttin… Amazing to see #PansPandasHour research put on the map! @NIHRresearch funds project to highlight existing studies + funding gaps. @wesstreeting @NHSinBlkCountry @NHSWYChair @nhsbobicb @BNSSGResearch @DavidGall64 @drjamiegreen @DrBenRiley @icbcdt
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Joanne Holloway retweeted
Viruses don’t just infect. They reprogram. New research suggests CMV and other herpesviruses may travel from the gut to the brain via the vagus nerve, triggering inflammation that alters cognition. Not just Alzheimer’s. 
In our clinic, we see reactivated EBV, CMV, HSV1, HHV-6 in kids with autism, PANS, regression. This isn’t rare.
 It’s just rarely tested. Gut. Brain. Microglia. Immune.
It’s all connected. Link to study in comments 👇 #Neuroinflammation #GutBrainAxis #PANS #PANDAS #Autism #ViralReactivation #CMV #EBV #HHV6 #Microglia #FunctionalMedicine #RootCause
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Joanne Holloway retweeted
Anti-NMDAR encephalitis occurs when an autoantibody cross-reacts with NMDA receptors in the brain. This can lead to psychosis, including, but not limited to: - visual hallucinations - delusions - catatonia - etc. A new paper finds one key difference in this type of psychosis compared to non-autoimmune forms of psychosis...🧵
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Joanne Holloway retweeted
Dr. Matt Cook drops a brutal truth on chronic fatigue syndrome: "Chronic immune stress from viruses living inside your cells steals energy directly from the mitochondria. That's why you have the best attitude in the world, you're Chris Williamson-level motivated… and you still can't fight your way out of it. This is super physiological—not psychological." 45 seconds that destroy the "just push harder" myth for anyone stuck in endless exhaustion. If you've battled chronic fatigue, did the "mindset/attitude" advice ever actually move the needle—or did it just make you feel worse for not being able to "will" your way out?
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If you’re chronically ill, how much sleep do you typically get a night?
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This Family Day, we honour families showing up for a loved one battling #PANS #PANDAS. Long appointments. Hard conversations. Small victories. Quiet courage. And when community shows up too, the weight feels lighter. Hope feels stronger. Healing feels possible. #FamilyDay
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Joanne Holloway retweeted
“Immunocompromised patients who had chronic COVID infections (>200 days) cleared the virus in under 2 weeks when given combo antivirals/monoclonals”
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Chronic illnesses aren’t all that rare. But them being diagnosed and believed is.
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Joanne Holloway retweeted
Scientists just cracked the Parkinson's disease code after decades. It all starts in your gut. And it's easily preventable. They've proven it across 5 countries with 94 patients. This changes everything we know about Parkinson's:
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Joanne Holloway retweeted
I’ve said this before and I’ll say it again. You can “do everything right” and still become chronically ill or disabled.
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Connective tissue disorders are a common comorbidity in those suffering from: - Long COVID - ME/CFS - MCAS - POTS What might be the thread that connects these conditions together? We recently surveyed the medical literature to find answers and published our findings on Jeannie Di Bon's blog, Founder and CEO of The Zebra Club. Here is what we found: jeanniedibon.com/me-cfs-eds-…
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Joanne Holloway retweeted
Nobody told you histamine could do this. Histamine is a daytime chemical. It rises with the sun and drops at night. In children with PANS and PANDAS, mast cells keep firing and it stays high. The body fights back with adrenaline. Adrenaline triggers more histamine. Histamine. Adrenaline. More histamine. Loop on loop. At night this looks like hyperactivity, anxious chatter, sudden irritability, sweating, flushed skin, restless legs, an OCD flare. Melatonin won’t touch it. This is chemistry stuck in fight-or-flight. If your child’s nights look like this, histamine is where I would start looking. #MastCells #Histamine #PANDAS #PANS #FunctionalMedicine
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Joanne Holloway retweeted
Delighted for this @NIHRresearch funded #PansPandasHour initiative! The evidence map reveals what’s known—+what still urgently needs research. panspandasuk.org/post/puttin… @Andrew4Pendle @DrGarethEThomas @ChrisOliver @aaroncummins @paukjebb1 @TabethaDarmon @claretwiggpeckh
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Joanne Holloway retweeted
panspandasuk.org/post/puttin… So excited to see this @NIHRresearch funded #PansPandasHour project! Mapping all existing research + highlighting the urgent need for more funding. @UniofExeter @GSTTnhs @MaudsleyNHS @KingsCollegeLon @xandvt @DrNighatArif @PhilipSimeITV @claudiahammond
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Joanne Holloway retweeted
Journalists: the new SEND reform risks leaving children with complex, fluctuating conditions like #PansPandasHour falling through the cracks. This needs scrutiny. @branwenjeffreys @alisonacton @PhilipSimeITV @jamiemroberton @ShaunLintern · @ascottgeddes @aoconnell @AmyPacker
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