Molecular biologist, virologist, cell biologist. Postdoctoral fellow at the Children's Hospital of Philadelphia.

Philadelphia, PA
Joined December 2019
Matthew Charman retweeted
The Microbiology Department at Penn is hiring Professors of all ranks, and I'm co-chairing the search committee with @SunnyShinLab/@BettsLab. Please RT and contact us if you have questions about the position and our department. apply.interfolio.com/148381 apply.interfolio.com/148380
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Congratulations to Nick Grams and @WeitzmanLab. I am looking forward to many more exciting discoveries on adenovirus packaging and biomolecular condensates in the near future!
Regulation of viral biomolecular condensates: Phosphorylation in the intrinsically disordered region #IDR of #adenovirus protein 52K modulates its liquid-like properties and function in viral packaging @WeitzmanLab and collaborators @PennMedicine embopress.org/doi/full/10.10…
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Matthew Charman retweeted
*Please share!* The Hogan Lab (hoganlab.org) at Penn is hiring our first lab tech to start ~1/2/24. Topics include mRNA vaccines, viral immunology, and T cell protection. Job ad & instructions here: wd1.myworkdaysite.com/recrui…
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📢VACANCY | 2 Senior Lecturer/Professor Positions Are you leading a programme in virology complementary with our research programmes? Join the CVR team! We encourage applications from women, minority ethnic groups & non-standard career paths. gla.ac.uk/explore/jobs/ Ref 125249
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Matthew Charman retweeted
Interested in the RNA biology of DNA viruses? So are we! Hopefully I captured that in this (first version) of a new Price Lab logo!
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Matthew Charman retweeted
Job posting is live for a research assistant/lab manager to join our new lab! Research will be focused on cellular RNA processing events hijacked by tumor-causing viruses. Please broadcast widely and reach out to me directly if you have any questions. us231.dayforcehcm.com/Candid…
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Matthew Charman retweeted
🚨Please RT!🚨 My lab is looking for a new Research Specialist to run our sequencing projects @pennvet! Previous folks in this role have gone on to PhDs and med/vet school. On-the-job training makes this a great opportunity for new grads 🎓! Apply below. bit.ly/3Uvw285
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We are excited to share our new work with you all 💧🔬🩸 "Heterotypic interactions in the dilute phase can drive co-condensation of prion-like low-complexity domains". Spearheaded by a fantastic postdoc @richoodavis. A longer thread will follow soon. biorxiv.org/content/10.1101/…
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Matthew Charman retweeted
Fully funded PhD opportunities at the University of Edinburgh here - ed.ac.uk/biomedical-sciences… Including one with Dr Richard Sloan and myself on viruses and IFITM proteins
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Fantastic findings that link microbiome, small RNAs, and inherited phenotypes. Congratulations all involved in this important discovery.
Check out the new work lead by my lab @TakuKambayashi lab, and the Grice lab at UPenn. We found in mice that the microbiome and immune system regulate a variety of phenotypes in progeny transgenerationally and that this may occur by regulating small RNAs in the gametes.
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Matthew Charman retweeted
Proud of our new work showing that biomolecular condensates and phase separation control viral packaging through molecular grammar of a viral protein. "Isn't that how all viral assembly works?" you ask. Yes, yes it is. But CNS editors would think that sounds boring.
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OUT NOW! 👉 A viral biomolecular condensate coordinates assembly of progeny particles by @WeitzmanLab and @CharmanMatthew published @Nature nature.com/articles/s41586-0…
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Thrilled to announce that our paper on adenovirus and biomolecular condensates was published today in @Nature. rdcu.be/c9e0d. What a fantastic achievement from everyone involved! @WeitzmanLab. I am really excited about where this will take our future research!
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8. In follow-up studies we are investigating how viral biomolecular condensates are regulated, and how progeny assembly is initiated when two pathways (phase-separated capsid proteins and newly synthesized viral genomes) converge.
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Anyone familiar with adenovirus knows that this virus uses a lot of fascinating molecular biology to replicate, but some of our early follow-up findings are exceptionally intriguing!
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