ALT Figure 1. The timeline of gene discovery in the epilepsies, including 126 manually reviewed genes across the three main eras of epilepsy gene discovery including the Channelopathy era, the Dark Ages, and the Genomic Era. Of note, not all genes contributing to the timeline are highlighted, but they are listed in a Supplement. The inset on the left highlights genes official review by our ClinGen Epilepsy Gene Curation Expert Panel (GCEP). Please note that this is v2 of the 2023 timeline and that future iterations may follow.