From 🇱🇰| Living in 🇦🇺| She/Her | Redmond Barry Distinguished Professor and Head of Allergy and Lung Health Unit @ALHU_MSPGH @UniMelbMDHS @unimelbMSPGH
Melbourne, Victoria
Joined February 2021
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Honoured to be elected as a @AAHMS_health fellow last night. Thank you to all my mentors, collaborators and @ALHU_MSPGH for their important contributions to my career. @UniMelbMDHS @unimelbMSPGH
A leader in the life course of chronic lung diseases, she has changed global understanding of how lung disease #COPD originates, leading to new practices, policy and a new field of research, pre-COPD.
Welcome Distinguished Prof @Cdharmage as a new #AAHMSFellow. @UniMelbMDHS
Shyamali C Dharmage retweeted
📣 EDITORS CHOICE:
Biomarkers of Pre-COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade
🖋️ Dinh S. Bui, Don Vicendese, Jonathan Pham, et al.
onlinelibrary.wiley.com/doi/…
Nice editorial on the statistical models used in the study on biomarkers of pre-COPD lung function trajectories.
🗨️ EDITORIAL: Heading in the Right Direction: Statistical Models for Lung Function Trajectories and Their Associations With Biomarkers
🖋️ Andrew Robert Gray
onlinelibrary.wiley.com/doi/…
on recent article:
onlinelibrary.wiley.com/doi/…
Another step towards identifying and treating those with progressive Pre-COPD. Great contribution by Tasmanian Logotudinal Health Study (TAHS)
📣 NEW ARTICLE: Biomarkers of Pre-COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade
#openaccess onlinelibrary.wiley.com/doi/…
Such a great editorial by Professors Licari and Corsico. The idea of "durable physiological signatures" is very useful for thinking about the impact of early events on later lung function.
We also appreciate the accompanying Comment from @LancetRespirMed on our FEF25–75% trajectory study. @CDharmage @ALHU_MSPGH
sciencedirect.com/science/ar…
Congratulations Jiachang on getting your last PhD paper in LRM. What a great paper to finish off your PhD - novel findings on MEF trajectories !!
Our study, based on data from TAHS, is now published in @LancetRespirMed. This study identified six FEF25-75% trajectories from age 7 to 53 years. Thanks to all co-authors for their insights and contributions. @CDharmage @ALHU_MSPGH
sciencedirect.com/science/ar…
I am honoured and humbled to have received this award. Thank you @nhmrc for supporting my research career over two and a half decades.
Recipient of the 2025 NHMRC Elizabeth Blackburn Investigator Grant Award for leadership in public health, @CDharmage has dedicated her research career to redefining COPD as a preventable life course condition, shifting the focus from late diagnosis to early intervention. Read more on Professor Dharmage’s career in her own words on our website: ow.ly/GCI750YUqAt
Congratulations on a landmark paper, @ProfJDChalmers
A study 10 years in the making, just published in @LancetRespirMed
How do DPP1 inhibitors really work in bronchiectasis?
We show a novel mechanism for treatment efficacy, by inhibiting Azurocidin-1, a ciliotoxin, DPP1i can enhance mucociliary clearance.
thelancet.com/journals/lanre…
I am honoured and deeply humbled by Elizabeth Blackburn Award for Leadership in Public Health. Thank you @NHMRC for supporting my career and research for nearly 2.5 decades.
Congratulations to each of the 2025 Research Excellence Awardees honoured tonight for their success and thank you for sharing NHMRC’s vision of building a Healthy Australia. Read the full list of award winners on our website: ow.ly/CYnf50YB1IC
Shyamali C Dharmage retweeted
Our latest paper just out in @LancetRespirMed
10 unanswered questions about DPP1 inhibition in bronchiectasis
We outline key future clinical and research questions after the approval of the first new therapy for people with bronchiectasis.
Congratulations Jiahui, Chloe and @MereteLong
Honoured to be highlighted by @nhmrc . Thank you for supporting our research.
Chronic Obstructive Pulmonary Disease (COPD) is common and treatable but often diagnosed too late. NHMRC funded researcher Professor Shyamali Dharmage (@MDHS_UniMelb) is leading a world first trial of triple therapy to halt lung damage in pre-COPD #WorldCOPDDay
Stay tuned for Cure-Adire. Time that we put our resources together. Funded by MRFF, this project will commence in early 2026. As the lead, I like to thank all the PIs of respiratory studies for coming together for this grant application.
Shyamali C Dharmage retweeted
Excited to learn about CURE-AIDRE which is a database of 75,000 asthma samples, decades in the making. It will be the engine to drive the search for treatments and cure. @CDharmage @tomiosifidis
Shyamali C Dharmage retweeted
🔓Now on Peeref: Paternal prepubertal passive smoke exposure is related to impaired lung function trajectories from childhood to middle age in their offspring
🔗: peeref.com/works/87260998
👁️: Altmetric: 285
@CDharmage @mishra_gita @ThoraxBMJ
Shyamali C Dharmage retweeted
I will be speaking on the role of biologics in #COPD as someone who is not funded by pharma
See you all in Philadelphia for #GOLD2025
GOLD has been central to shaping how we define and manage COPD, and its legacy continues.
#COPD
#cureCOPD
@Hananianick @suryapbhatt @donsin4 @PavordIan @meilan_han
Thanks for highlighting this important work
💬"Exposure to passive (second-hand) smoke🚬 not only harms the children at that time but may also affect the lung health of their future children,” Dinh S. Bui, PhD, and @CDharmage, MBBS, MSc, MD, PhD, @unimelbMSPGH, told Healio.
healio.com/news/pulmonology/…
Lets promote and advance the field of pre-COPD. Recognising and tackling the pre-disease and early disease states have helped reducing the burden of many chronic diseases, so why not in COPD? thelancet.com/journals/lanre…
Grateful to @LancetRespirMed for the kind profile. Honoured and humbled to be featured. Thank you.
Shyamali Dharmage: mapping lung health trajectories across the life course - The Lancet Respiratory Medicine thelancet.com/journals/lanre…
Congratulations Caroline and the team!
🎉 Congrats to Caroline Lodge and her team @daisydai28 @CDharmage @rcatham
@AnurikaDeSilva on receiving a $965K NHMRC TCR – Climate-Related Health Impacts grant!
They will explore HEPA filters to improve quality of life for people with asthma during high air pollution events.
Congratulations Daisy and the team!
🎉 Big congratulations to Daisy @daisydai28 and her team @NatashaSmallwo4 @CDharmage @AnurikaDeSilva on receiving a $647K MRFF EMCR grant!
Her project OVERNIGHT will use HEPA filters to help reduce exacerbations in older adults with COPD during air pollution events.
Shyamali C Dharmage retweeted
#cannabis smoking causes widespread disruption in blood methylome...something we also see with #tobacco smoking...data from @HLIStPauls @queensu @mcgillu with funding from @CIHR_IRSC
Cannabis smoking makes numerous changes to the epigenome that last even after a person stops smoking, which may negatively affect future health
tinyurl.com/488z3vyk
