@CascalesLab

How to specifically select a protein from one side of the membrane and to transport it on the other side ? That's what we will love to understand. #T6SS #T9SS

 Marseille, France
cascaleslab.fr/home/
Joined July 2015
  • Tweets3K
  • Following2.4K
  • Followers4.6K
161Media
Quelle tristesse. Un grand monsieur et un ami qui s'en va ! Je me rappellerai longtemps de ta gentillesse, de ton humilité, et des conseils précieux. Toutes mes condoléances à Anne.
CNRS 🌍
@CNRSOct 15
[HOMMAGE] Le CNRS a appris avec une grande tristesse le décès de Pierre Joliot, pionnier de la photosynthèse et figure de la recherche au CNRS. Nos condoléances à sa famille et à ses proches. 👉 insb.cnrs.fr/fr/cnrsinfo/hom…
Hommage à Pierre Joliot, pionnier de la photosynthèse et figure de la recherche au CNRS

ALT Hommage à Pierre Joliot, pionnier de la photosynthèse et figure de la recherche au CNRS

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Interested to join our team for your PhD ? We are looking for highly motivated PhD fellows ! Please contact us to apply through the France Excellence Eiffel Scholarship programme ! campusfrance.org/en/france-e…
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Dor Salomon@DrDorSalomonOct 8
If you're interested in doing a postdoc with us on #T6SS #MGE, have a look at this opportunity for the prestigious Azrieli postdoc fellowship azrielifoundation.org/fellow…

International Postdoctoral Fellowship - The Azrieli Foundation

The Azrieli Fellows Program is an elite group of academics who cultivate a network of leading professionals in Israel and around the world.

azrielifoundation.org
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Marc Erhardt@Salmo_LabOct 7
How do bacteria build their flagella? We’ve put together an animation of Salmonella flagellum assembly based on cryo-EM and X-ray structures. From the membrane-embedded machinery to the growing filament, here’s how the parts come together, step-by-step.
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Basler Lab@Basler_LabOct 7
When Pseudomonas is attacked, it strikes back! Outer membrane damage triggers a tit-for-tat T6SS retaliation via TagQ/TagR protein complex assembly, activating the PpkA kinase. Congrats to Maxim & team for uncovering this fascinating mechanism! nature.com/articles/s41467-0…

Membrane damage induces TagQ/TagR complex-mediated H1-T6SS assembly in Pseudomonas aeruginosa

Nature Communications - The H1-T6SS of Pseudomonas aeruginosa assembles in response to membrane damage. Here, the authors show that this response mechanism is regulated by the formation of a...

nature.com
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New study in @NAR_Open 🧬 A #T6SS-delivered Rhs toxin from Chromobacterium violaceum, TreThr, is an ADP-ribosyltransferase that selectively modifies charged tRNAThr(GGU), blocking ACC codon decoding & shutting down protein synthesis in rival bacteria. academic.oup.com/nar/article…
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This work complements the study of Jùlia Alves, José da Silva Neto and @SarahCoulthurs1 published earlier this year: jbc.org/article/S0021-9258(2…

Global identification of Chromobacterium violaceum T6SS effectors reveals an Rhs antibacterial...

Bacteria coexist in polymicrobial communities where they engage in complex interactions, including interbacterial antagonism. The environmental bacterial pathogen Chromobacterium violaceum possesses...

jbc.org
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New in @CurrentBiology 🦠 Why do bacteria ditch their T6SS weapon? Experimental evolution shows that E. coli keeps it vs susceptible rivals, but loses it when facing immune ones. Great work @bTaillefer_ @JonasDesjardins! cell.com/current-biology/abs…
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Very proud to see our review "Anti-type VI tactics: bacterial defenses against T6SS attacks" featured on the Cover of @TrendsBiochem cell.com/trends/biochemical-… Kudos to @NicolasRivard11 for creating this fantastic Cover illustration! But… do do you recognize the original painting?
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Basler Lab@Basler_LabAug 12
Interested in the Function and Regulation of #T6SS? Do you have relevant experience from your Master's project? Apply to this PhD position in our lab: biozentrum.unibas.ch/open-po…

PhD Student – Function and Regulation of Type 6 Secretion System

biozentrum.unibas.ch
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Happy to share our latest review on the "Structure and function of the #T9SS for protein secretion and cellular motility" to be published in the incoming volume 80 of Annual Review in Microbiology. Kudos to Yaelle Aouizerate and @doan_thierry ! annualreviews.org/content/jo…
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Erh-Min Lai@erhminlaiAug 5
Our lab is recruiting people at multiple levels: postdoc, graduate student, and RA @IPMBSinica #Taiwan to investigate the evolution and molecular mechanisms of #Agrobacteria #T6SS antibacterial weapon. Check out the job ad and the lab website! Please apply or RT
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Extension of the deadline for latecomers. Register to the Secretion Days in Marseille ! 📅 Secretion Days 2026: October 8-9 in Marseille 🌊 🎤Invited speaker : Wilbert Bitter; @wilbertbitter 🆓 Free ! 📥 Register here: docs.google.com/forms/d/e/1F…

Journées Sécrétion 2026

Contact: [email protected]

docs.google.com
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Happy to share the last publication of @bTaillefer_, showing that #T6SS heterogeneity is an attenuation strategy to optimizes the trade-off between competitive killing and survival. @PLOSBiology journals.plos.org/plosbiolog…
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Happy to share the last work of Jonas @JonasDesjardins, identifying and characterizing a novel Rhs NAD(P) glycohydrolase delivered by the #T6SS of the major cosmetic contaminant, Pluralibacter gergoviae. jbc.org/article/S0021-9258(2…
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Marc Erhardt@Salmo_LabMay 11
Postdoc opening in my lab @HumboldtUni! Join our Einstein Foundation-funded collaboration with the Hebrew University of Jerusalem on T3SS, spatial RNA localization, imaging & bacterial cell biology. 📅 Apply by 2 June 2026 🔗 hu.berlin/T3SSjob #Postdoc #Microbiology
🤖 Made with AI
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T2SS ? T4SS ? CDI ? T6SS ? T7SS ? NO ! The #T9SS is also involved in interbacterial competition !! @CurrentBiology Great work by Maelle Paillat @maelle_paillat under the supervision of Thierry Doan @doan_thierry sciencedirect.com/science/ar…
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Glad to share our latest review on the diversity of defense mechanisms against the T6SS! “Anti-type VI tactics: bacterial defenses against type VI secretion system attacks” is available in Trends in Biochemical Sciences right now. @CascalesLab @jpcotelab authors.elsevier.com/c/1msKv…
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Very happy that our work on the T6SS ADP-ribosylcyclase toxin made the Cover at JBC @jbiolchem ! Congratulations Julius @MartinkusJM for designing this Cover ! @DukasJu @LaurentTerradot
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Happy to share the last work of Julius (@MartinkusJM) led by Dukas Jurenas. Poly-immunity arrays associated with Rhs and CDI toxins and linked to a novel genetic element (XPC cassette) confer protection against competitors. @CurrentBiology Kudos !! cell.com/current-biology/ful…

Poly-immunity arrays associated with Rhs toxins confer wide protection against competitors

Martinkus et al. show that Photorhabdus and Xenorhabdus species encode arrays of immunity genes whose protein products neutralize toxins secreted by competitors. These arrays, often linked to Xer...

cell.com
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