@C__Hahn

Biology, Bioinformatics | husband & father | curious, fascinated, frustrated, exhausted, excited, hungry, surprised ..

github.com/chrishah
Joined October 2014
  • Tweets1.4K
  • Following192
  • Followers246
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nature.com/articles/s41587-0…
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Our preprint is out! We hacked the @nanopore sequencer to read amino acids and PTMs along protein strands. This opens up the possibility for barcode sequencing at the protein level for highly multiplexed assays, PTM monitoring, and protein identification! biorxiv.org/content/10.1101/…

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid...

The ability to sequence single protein molecules in their native, full-length form would enable a more comprehensive understanding of proteomic diversity. Current technologies, however, are limited...

biorxiv.org
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Christoph Hahn retweeted
Jeff Nivala@jeffnivala21 Oct 2023
Yesterday we released our preprint showing how a @nanopore array morphs into a protein sequencer... Achieving LONG reads (hundreds of amino acids) and the capability to re-read individual molecules multiple times, all thanks to a protein-processive molecular motor.
Keisuke Motone / 元根 啓佑@KeisukeMotone21 Oct 2023
Our preprint is out! We hacked the @nanopore sequencer to read amino acids and PTMs along protein strands. This opens up the possibility for barcode sequencing at the protein level for highly multiplexed assays, PTM monitoring, and protein identification! biorxiv.org/content/10.1101/…

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid...

The ability to sequence single protein molecules in their native, full-length form would enable a more comprehensive understanding of proteomic diversity. Current technologies, however, are limited...

biorxiv.org
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Christoph Hahn retweeted
NatureEcoEvo@NatureEcoEvo20 Oct 2023
Evolutionary dynamics of whole-body regeneration across planarian flatworms nature.com/articles/s41559-0…
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Embracing the command line: my unexpected career in computational biology nature.com/articles/d41586-0…

Embracing the command line: my unexpected career in computational biology

Nature - A crash course in bioinformatics put Ming Tommy Tang on a different path.

nature.com
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Great news from COPO! Reliably brokering sample #metadata is an essential step of the reference #genome production workflow. Congratulations on this impressive milestone 🎉 @BioGenEurope @EarlhamInst
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Structural #genome annotation with BRAKER & TSEBRA - workshop will take place on the 21st Nov. from 9am to 3pm, registration is free but capacity is limited to 35 participants - so hurry! cognitoforms.com/ERGAEuropea… #training #bioinformatics #genomics #biodiversity @erga_biodiv ERGA
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NENG HUANG@csuhuangneng28 Sep 2023
Thrilled that our work “compleasm: a faster and more accurate reimplementation of BUSCO” is now published in Bioinformatics! 🎉 Huge thanks to our amazing lab @lh3lh3 and to the reviewers’ valuable comments. 🙏 Journal paper: academic.oup.com/bioinformat…
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Dave Moi@steg0s4urus24 Sep 2023
In a post #AlphaFold world, we can use protein structures in ways we never could before. Can we build phylogenies with them? Are they any good? Yes! Foldtree (biorxiv.org/content/10.1101/…) surpasses traditional sequence-based methods, even for closely related proteins.👇
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Indeed, thanks @philippresl, @EcoEvoGraz, @UniGraz. Check it out - even if you're not interested in #phylogenetics. It's about democratizing complex computational analyses and #reproducibiltiy through #scalability and #portability (#containers)..
Philipp Resl@philippresl24 Sep 2023
Interested in #phylogenetics using whole #genome/#transcriptome/#proteome data? @C__Hahn and I are very happy to share phylociraptor with you: It facilitates explorative and reproducible phylogenomic analyses of thousands of genes and genomes. Preprint: tinyurl.com/yc4f7v6d
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Philipp Resl@philippresl24 Sep 2023
Replying to @philippresl @C__Hahn
Available on GitHub: github.com/reslp/phylocirapt…

GitHub - reslp/phylociraptor: rapid phylogenomic tree calculator - A highly customizable framework...

rapid phylogenomic tree calculator - A highly customizable framework for reproducible phylogenomic inference - reslp/phylociraptor

github.com
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Christoph Hahn retweeted
Philipp Resl@philippresl24 Sep 2023
Interested in #phylogenetics using whole #genome/#transcriptome/#proteome data? @C__Hahn and I are very happy to share phylociraptor with you: It facilitates explorative and reproducible phylogenomic analyses of thousands of genes and genomes. Preprint: tinyurl.com/yc4f7v6d
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bioRxiv@biorxivpreprint24 Sep 2023
Phylociraptor - A unified computational framework for reproducible phylogenomic inference biorxiv.org/cgi/content/shor… #bioRxiv
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Phylociraptor - A unified computational framework for reproducible phylogenomic inference biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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Our CARD pilot paper with @KimberleyBill10 @cornelisblauw @BenedictPaten and many others is online! We establish a wet + dry lab protocol for single nanopore flow cell sequencing, which generates state-of-the-art SNP and SV calls + assemblies. rdcu.be/dl901
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Christoph Hahn retweeted
Kenny Workman
@kenbwork14 Sep 2023
Snakemake has many technical benefits over Nextflow for writing bioinformatics workflows. But there is no platform that supports the language. Today we are releasing native support for Snakemake on the LatchBio Cloud. blog.latch.bio/p/native-snak…

Native Snakemake Support on LatchBio

Bioinformatics in Python on the Cloud for Biology

blog.latch.bio
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The small variant calling benchmarking initiative of @NGSCN1 is published. Thanks a lot to all the contributors and @dfg_public for the funding. (1/x)
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Visual opsin gene expression evolution in the adaptive radiation of cichlid fishes of Lake Tanganyika | Science Advances science.org/doi/10.1126/scia…

Visual opsin gene expression evolution in the adaptive radiation of cichlid fishes of Lake Tangan...

Retinal transcriptomes of Lake Tanganyika cichlids reveal changes in the expression of visual opsin genes associated with ecology.

science.org
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Christoph Hahn retweeted
Javier Santoyo@jsantoyo12 Aug 2023
Assessment of metagenomic workflows using a newly constructed human gut microbiome mock community. #Metagenomics #MicrobiomeMockCommunity #DNAresearch academic.oup.com/dnaresearch…

Assessment of metagenomic workflows using a newly constructed human gut microbiome mock community

Abstract. To quantify the biases introduced during human gut microbiome studies, analyzing an artificial mock community as the reference microbiome is indi

academic.oup.com
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How do you stress the importance of replicates to improve the accuracy of #eDNA sampling? Use pizza of course 🍕🍕🍕 A great talk by @N_P_Griffiths #fishimp2023
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