Collaborative programme to support the development of marketable products that have an impact on business & the 3Rs from @NC3Rs. Technology for Better Science.
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Joined September 2011
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Please note that this account will be closed at the end of February. You can follow the NC3Rs on LinkedIn linkedin.com/company/nationa… or Bluesky bsky.app/profile/nc3rs.bsky.… and subscribe to the monthly newsletter for our latest innovation updates nc3rs.org.uk/nc3rs-newslette….
ALT Graphic showing three 3Rs-related images: zebrafish in a tank, mice been handled using non-aversive handling techniques and a multi-channel pipette distributing pink solution into a 96-well plate.
⏳ There is one week left to submit your 3Rs Challenge idea for the 2025 CRACK IT open call. Download the form today and submit to [email protected] by Monday 10 February: nc3rs.org.uk/crackit/sponsor…
⏰ The CRACK IT open call for 3Rs Challenges closes on Monday 10 February. If your organisation is facing a scientific or research challenge that could be solved with a 3Rs approach, get in touch to discuss and submit your idea to sponsor a Challenge.
👉 nc3rs.org.uk/crackit/news/su…
ALT Megaphone icon: open call for 3Rs challenges
We have awarded £300k to advance the development of new approach methodologies (NAMs) to replace the use of birds in toxicity testing as part of the Wings of Change Challenge: nc3rs.org.uk/crackit/news/ps…
ALT Graphic showing a flying mallard duck, which is one of the bird species used in avian toxicity testing, with a test tube and computer screen on either side representing development of new approach methodologies to reduce reliance on in vivo studies in birds.
⏰ The CRACK IT open call for 3Rs Challenges closes on Monday 10 February. If your organisation is facing a scientific or research challenge that could be solved with a 3Rs approach, get in touch to discuss and submit your idea to sponsor a Challenge.
👉 nc3rs.org.uk/crackit/news/su…
ALT Megaphone icon: open call for 3Rs challenges
CRACK IT retweeted
🧪💊We have awarded a team from Toxys £1M to further develop in vitro and in silico approaches that better predict developmental toxicity in drug development and reduce reliance on in vivo embryo-fetal developmental studies: nc3rs.org.uk/crackit/news/ps…
ALT Close up of a pipette dropping liquid into a a test tube.
CRACK IT retweeted
Do you have an idea to improve R&D in your organisation and refine or reduce reliance on in vivo studies? We are inviting new Challenge ideas for the 2025 @CRACK_IT competition.
Visit the Innovation Platform to find out more:
nc3rs.org.uk/crackit/news/su…
ALT Megaphone graphic with text: Open call for 3Rs Challenges.
REMINDER: Applications to solve our 2024 CRACK IT Challenges close Monday 4 November.
You can find information and support to complete and submit your application on the Innovation platform including launch webinars, Q&As and full Challenge information: nc3rs.org.uk/crackit/view-ch…
🦆 Wings of Change: Developing NAMs to assess acute and chronic avian toxicity for chemical screening and environmental risk assessment.
Challenge details and webinar recording: nc3rs.org.uk/crackit/wings-c…
LinkedIn networking group: linkedin.com/groups/13095362…
🐭 Rodent Shelter: Developing a shelter to refine rodent post-operative care.
Challenge details and webinar recording: nc3rs.org.uk/crackit/rodent-…
LinkedIn networking group: linkedin.com/groups/13095361…
📣 £2.1M funding is available to solve two new CRACK IT Challenges:
Wings of Change: developing new approach methodologies for avian toxicity.
Rodent Shelter: developing a shelter to improve post-operative recovery and monitoring of rodents.
Details: nc3rs.org.uk/crackit/news/ps…
CRACK IT retweeted
Register now for our joint webinar with @HESI_Global next week.
More details 👇
Our webinar with @HESI_Global will explore the Virtual Second Species @CRACK_IT Challenge harnessing computational approaches and machine learning to develop a Virtual Dog and ultimately replace their use for chronic toxicity studies.
📅Wednesday 29 May
👉nc3rs.org.uk/events/machine-…
ALT Representation of a digital network with bright dots interconnected by grey lines.
We have awarded £600k for proof-of-concept studies to accelerate the development of New Approach Methodologies, focusing on advancing the utility and reproducibility of organ-on-chip technologies and improved in vitro assays for developmental toxicity 🎉 nc3rs.org.uk/crackit/news/ps…
CRACK IT retweeted
Did you hear our Head of Toxicology, Dr Fiona Sewell on the Today programme @BBCRadio4 this morning? Listen from 2:49:00 to hear her discuss our Virtual Two Species project which aims to replace the use of the dog in chronic toxicity studies: bbc.co.uk/sounds/play/m001wh…
Proud to have been a part of @NewcellsBiotech journey and growth, investing £2.9M through CRACK IT Challenges to develop their human tissue models, including a retinal organoid to replace animals in preclinical studies for opthalmologic drugs: nc3rs.org.uk/crackit/retinal…
UK’s Newcells Biotech snaps £2.35M for its 3D alternative to animal testing techfundingnews.com/uks-newc… via @TFNBreakingNews
There are two weeks left to submit your Challenge idea to address an unmet research question and 3Rs need. Sponsors provide in-kind support and end-user input and receive early access to new technologies.
📅 Deadline for submissions: Friday 16 February.
👉 nc3rs.org.uk/crackit/news/sp…
ALT A lightbulb made of connected lines and dots, in white on a blue background. Text reads 'CRACK IT 2024 Call for Challenges'.
🎉 We have awarded £1M to a team @UniFreiburg to solve the T-ALERT Challenge to replace some animal studies in the safety assessment of human engineered T cell therapies. This marks a total CRACK IT Challenge investment of £4.8M in cell and gene therapies: nc3rs.org.uk/crackit/news/ps…
The T-ALERT Challenge is supported by @HESI_Global in collaboration with five pharmaceutical industry Sponsors @Novartis @TakedaPharma @AstraZeneca @sonomabio @GentiBio. Find out more on the Challenge page: nc3rs.org.uk/crackit/t-alert
Last chance to apply for the reopened aTRACKtive Challenge before the deadline tomorrow at 12.00 (GMT)! Find out more about the Challenge below and apply on our Innovation Platform: nc3rs.org.uk/crackit/apply-s…
The aTRACKtive Challenge deadline is fast approaching. Apply for up to £100k to develop non-invasive and non-toxic methods to identify individual mice from birth. Approaches including wearables are now within remit.
Deadline: Thursday 4 January, 12.00 GMT
nc3rs.org.uk/crackit/atrackt…
ALT Image of seven white mice in the corner of their caging. The sides of the cage are transparent and the bottom is filled with wood chips.
Calling experts from industry, charities and academia – If you have a research question that could be solved with a 3Rs driven approach, submit your Challenge idea for the 2024 CRACK IT competition. Hear what our Sponsors had to say about their experience: nc3rs.org.uk/crackit/news/sp…
ALT The CRACK IT logo above text reading '2024 Call for Challenges', in white on a blue background. Accompanied by a graphic of a lightbulb made of connecting white dots and lines.