When 100+ spreading depolarizations run through the temporal lobe of a brain injured human being, the question of treatment goes beyond academic musings. We need answers.
Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury ja.ma/35dl4J9
Today marks 75 years of spreading depression research! August 14, 1944, Leão's landmark paper was received for publication in @JNeurophysiol. It would take 58 years for Leão's work to be translated to the clinic, sparking a #SpreadingDepolarizations Renaissance! #TBI #stroke #SAH
Thanks to Drs. Suzuki and Oka for hosting another excellent COSBID meeting - the first in Asia - in Yokohama, Japan. Excellent discussions and science among a very thoughtful group. #spreadingdepolarizations
Monitoring infraslow waves of brain injury (#spreadingdepolarization) with graphene transistors - on the cover of Nature Materials!
COSBID retweeted
Headed to #NTS2019 organized by @neurologyrules. Looking forward to seeing @cgzammit @MobergICU @SurgeonScience and many others! #neurocritical #ICU – at Queens, NY
If you haven't already, please be sure to register for this year's #COSBID2019 in Yokohama, Japan!
cosbid.org/meeting/current/ or see icsd2019.jp/ for more information!
COSBID retweeted
Very good visualizations of cortical spreading depolarizations #AANAM
Radial, spiral and reverberating waves of spreading depolarization occ... sciencedirect.com/science/ar…
The Continuum of #spreadingdepolarizations is the SECOND most cited reference @_JCBFM of the last three years! Congrats to the @JedHartings and co-authors!
journals.sagepub.com/home/jc…
COSBID retweeted
A case of amyloid angiopathy presenting with 15-20 min transient neuro symptoms (‘amyloid spells’) related to migraine-like #spreadingdepolarizations. Characteristic MRI and biopsy confirmed the diagnosis! @COSBID #AANAM
Fascinating work! #AANAM
Looking forward to presenting our work from @UofR @URNeuroscience on the role of the #glymphatic system in driving cerebral edema after acute ischemic stroke tomorrow at #AANAM @AANMember. Stop by room 118A at 3:50pm!
Frontiers in Neuroscience plenary with @JedHartings at #AANAM explaining the remarkable prevalence of #spreadingdepolarizations and its role in excitotoxicity after brain injury #NeuroCC #stroke #tbi @UCNeuroPMR @UCNeurosurgery @UCHealthNews @AANMember
Brain tsunamis in stroke highlighted in the Albuquerque Journal! #cosbid #spreadingdepolarization
Battling the effects of cerebral tsunamis abqjournal.com/1301127 #abq via @abqjournal
COSBID retweeted
Why isn't there a perfect animal model for aneurysmal subarachnoid hemorrhage? We wrote this article to try answering the question, and to start a conversation about what sorts of outcomes matter for translation to patients. rdcu.be/bsWKf link.springer.com/article/10…
COSBID retweeted
Recording of Sharon Jewell's Spreading Depolarizations webinar now available. - mailchi.mp/2ca2ebc8bd92/psh6…
COSBID retweeted
A technical guide to imaging cerebral blood flow in rodents @_JCBFM from David Kleinfeld's lab @UCSDNeuro @UCSDHealth @UCSDnews - Two-Photon Microscopy to Study Blood Flow and Neurovascular Coupling journals.sagepub.com/doi/pdf…
Friday March 1st join @MobergICU for a #BrainMatters webinar featuring Sharon Jewell with @KingsCollegeLon. See below for registration information! #spreadingdepolarizations
Just ONE WEEK until our next #BrainMatters webinar! Join us on March 1st at 1pm EST to learn more about spreading depolarizations in the injured brain with Sharon Jewell.
Register here: zoom.us/webinar/register/WN_…
Interesting study! Especially in light of recent work on cilostazol (also inihibits plt aggregation and promotes vasodilation via phosphodiesterase inhibiton). Wonder what the effects of terutroban are on #spreadingdepolarizations? #SAH
Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats
#FOAMcc
bit.ly/2SrYMSf
COSBID retweeted
The first successful targeting of spreading depolarizations in patients with subarachnoid hemorrhage. Cilostazol decreases the sequela of SDs after SAH and demonstrates how SDs can affect outcome after #SAH. @COSBID onlinelibrary.wiley.com/doi/…