Validating AI in classifying colorectal cancer in real-time surgery. Funded by @HorizonEU. Tweets reflect only the views of the project owner.

Joined May 2022
πŸ‡ͺπŸ‡Ί CLASSICA | Validating AI in Classifying Cancer in Real-Time Surgery πŸ’‘ Five leading cancer surgery centres across Europe will treat 500 patients during the project. Check out our website to learn more πŸ‘‰ classicaproject.eu/ #HorizonEU #classica #ai #colorectal #cancer
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πŸ“£ Interested in seeing CLASSICA's platform in action? πŸ“Ή Check out our new educational video from project partners @ucddublin, @IrcadFrance and Arctur. Prof @RonanCahill15 (University College Dublin), Prof John Burke (Beaumont University Hospital), Ed Murphy (University College Dublin) and @samo_erzen (Arctur) share how CLASSICA β€˜s next-generation AI platform can enhance detection of cancer in real-time in surgical settings. classicaproject.eu/2026/09/c…
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πŸ“Ή Check out our new promotional video from project partners @ucddublin and @IrcadFrance! The video showcases the main elements of the CLASSICA project. CLASSICA transforms fluoresecence imaging into real-time clinical intelligence that can be used in operating rooms to improve colorectal cancer treatment decisions. The innovative Artificial Intelligence tool developed by the project is now under multi-centre clinical evaluation. classicaproject.eu/2026/09/c…
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CLASSICA clinical partner Prof. Felix Aigner @FelixAigner2 was at the European Federation for Colorectcal Cancer’s 14th EFR Congress 2026 in Vienna last week. The EFR Congress serves as a central meeting point for experts in surgery, oncology, and gastroenterology. The theme of the congress this year was β€˜Beyond Boundaries: From Microbiome Research to Robotic Surgery in Rectal Cancer’. The event hosted more than 100 participants joined by 40 speakers over 3 days. Prof Aigner spoke about β€˜Transanal Surgery for Rectal Cancer: From Basic Techniques to Artificial Intelligence’ and highlighted the CLASSICA project.
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πŸ“š Knowledge Unwrapped: πŸ‡ͺπŸ‡Ί CLASSICA project's publication lay summary series looks at the latest paper from the team! A recent CLASSICA paper, Privacy Considerations of Artificial Intelligence Scribes, in NEJM AI examined how Artificial Intelligence (AI) scribes handle, store, and destroy data acquired during a patient encounter. Authors Dr Sara Gerke and Prof David A. Simon made recommendations for hospitals to consider when adopting these tools, including training procurement teams, disclosing and obtaining consent for use of AI scribes, and developing data governance policies. Read our capsule summary of the publication here πŸ‘‰πŸ½ classicaproject.eu/2026/06/k…
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πŸ“15–16 June 2026, CLASSICA partners participated in two days of productive discussions, knowledge exchange, and collaboration, as well as a dedicated exploitation workshop focused on defining the next steps towards ensuring the long-term impact and sustainability of the project's results. πŸ™ŒA big thank you to or hosts - we look forward to the exciting work ahead! #HealthcareInnovation #artificialintelligence #machinelearning #MedicalResearch
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Training is an important part of CLASSICA's dissemination work. Coordinator Prof Ronan Cahill joined the European Society of Surgical Oncology (ESSO) - International Society for Fluorescence Guided Surgery (ISFGS) Course in Leiden on 11th June 2026, where he spoke about the kinetics of fluorescence in cancer imaging. #HORIZONEU #SurgicalInnovation
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Read our summary of a @classicaproject study in the Journal of Law and the Biosciences examining whether Europe's landmark AI law will actually make AI systems fairerβ€”particularly in healthcare. Authors Emilia Niemiec, Peter A E Davis (both at CeBIL, @UCPH_Research), and Mathias K Hauglid (Wikborg Rein Advokatfirma AS) take a close look at the EU AI Act's rules around training data, asking whether they're strong enough to tackle one of AI's most persistent problems: biased datasets. πŸ”—classicaproject.eu/2026/03/k…
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πŸ”¬ New Surgical Endoscopy publication summary from the @classicaproject team, π‘·π’†π’“π’Šπ’•π’π’π’†π’‚π’ π’π’‘π’†π’π’Šπ’π’ˆ π’…π’–π’“π’Šπ’π’ˆ 𝒕𝒓𝒂𝒏𝒔𝒂𝒏𝒂𝒍 π’†π’π’…π’π’”π’„π’π’‘π’Šπ’„ π’Žπ’Šπ’„π’“π’π’”π’–π’“π’ˆπ’†π’“π’š: 𝒄𝒂𝒏 π’‘π’“π’†π’π’‘π’†π’“π’‚π’•π’Šπ’—π’† π’‘π’π’”π’Šπ’•π’Šπ’π’π’Šπ’π’ˆ π’‚π’”π’”π’†π’”π’”π’Žπ’†π’π’• π’Šπ’Žπ’‘π’“π’π’—π’† π’Šπ’π’•π’“π’‚π’π’‘π’†π’“π’‚π’•π’Šπ’—π’† π’Žπ’‚π’π’‚π’ˆπ’†π’Žπ’†π’π’•? Peritoneal opening during TEM/TEO surgery is largely predictable, and when well-managed, doesn't increase overall patient risk. Important findings for safer surgical planning. πŸ₯ πŸ‘‰ @albertoarezzo, Ammirati, Distefano et al., @unito #MinimallyInvasiveSurgery #Colorectal #TEM #KnowledgeUnwrapped πŸ“š classicaproject.eu/2026/03/k…
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Now published open access online @SurgEndosc β€œPerioperative splanchnic perfusion variation around colorectal surgery using both indocyanine green spectrophotometry and fluorescence angiography” @ucdmedicine @jeffreydalli @Ashokk_s access via the link…links.springernature.com/f/a…~
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🩺 New evidence in #TEM surgery What predicts peritoneal opening during transanal endoscopic microsurgeryβ€”and does patient positioning matter? A Feb 2026 study in Surgical Endoscopy from @unito (@albertoarezzo et al.) shows that peritoneal opening during TEM is anatomically predictable based on lesion features and positioning.πŸ”Ž Key takeaways: β€’ Predictable risk based on anatomy & positioning β€’ Higher conversion rates & longer LOS β€’ No significant increase in morbidity when promptly recognised and managedπŸ‘¨β€βš•οΈ Authors: Alberto Arezzo, Carlo Alberto Ammirati, Giovanni Distefano, Michele Barbiero, Simone Arolfo, Mario Morino πŸ“– Read more πŸ‘‰πŸ½ classicaproject.eu/2026/03/c… πŸ”— Article πŸ‘‰πŸ½ link.springer.com/article/10… #ColorectalSurgery #MinimallyInvasive #SurgicalEndoscopy #PatientSafety #TEM
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In an August 2025 πŸ‡ͺπŸ‡Ί @classicaproject publication in npj Digital Medicine, 'π‘¬π’π’‚π’ƒπ’π’Šπ’π’ˆ 𝒔𝒆𝒄𝒖𝒓𝒆 𝒂𝒏𝒅 𝒔𝒆𝒍𝒇 π’…π’†π’•π’†π’“π’Žπ’Šπ’π’†π’… 𝒉𝒆𝒂𝒍𝒕𝒉 𝒅𝒂𝒕𝒂 π’”π’‰π’‚π’“π’Šπ’π’ˆ 𝒂𝒏𝒅 𝒄𝒐𝒏𝒔𝒆𝒏𝒕 π’Žπ’‚π’π’‚π’ˆπ’†π’Žπ’†π’π’•,' CLASSICA PI @TiMinCeBIL, @CeBIL_Center, @UCPH_Research, with co-authors Cindy Welzel, TU Dresden, Max Ostermann, Technische UniversitΓ€t Dresden, Hannah Louise Smith, University of Copenhagen (KΓΈbenhavns Universitet), @toralf_kirsten, Leipzig University, and Stephen Gilbert, Technische UniversitΓ€t Dresden, presented a conceptual framework for secure and self-determined health data sharing, discussing how emerging digital technologies can support trustworthy consent management. This research aims to explore how people can gain meaningful control over how their health data, which can be generated by apps and wearable devices, is shared and used for healthcare and research. Why is this research important? Check out our easy-to-digest, β€œKnowledge Unwrapped” summary πŸ‘‰πŸ½ classicaproject.eu/2026/02/k…
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How does the EU AI Act address dataset quality and bias in AI systems, and what are the practical and legal implications of these provisionsβ€”particularly regarding data governance, the "debiasing exception" for sensitive data, and enforcement mechanisms? βš–οΈ Authors of the Journal of Law and the Biosciences article, "π‘Ύπ’Šπ’π’ 𝒕𝒉𝒆 𝑬𝑼 𝑨𝑰 𝑨𝒄𝒕 𝒉𝒆𝒍𝒑 𝒕𝒐 π’Žπ’Šπ’•π’Šπ’ˆπ’‚π’•π’† 𝒅𝒂𝒕𝒂𝒔𝒆𝒕 π’ƒπ’Šπ’‚π’” π’Šπ’ π’Žπ’†π’…π’Šπ’„π’‚π’ 𝑨𝑰?", @classicaproject researcher Emilia Niemiec, @CeBIL_Center, University of Copenhagen, Peter Davis, CeBIL, U of Copenhagen, and Mathias K. Hauglid, Wikborg Rein Advokatfirma AS, examine how Europe's new AI law tries to make AI systems fairer by setting rules about the data used to train them, requiring representative datasets and even allowing use of highly-protected sensitive data specifically to fix bias problems. The authors analysed whether these rules will work in practice, especially in medical AI, given the tension between accessing data to check for bias and protecting patient privacy. Read on πŸ‘‰classicaproject.eu/2026/02/c…
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πŸ“£ Publication news! @CLASSICAproject explores how AI analysis of fluorescence perfusion can support in-situ classification of significant rectal polyps. πŸ“„ "π‘¨π’“π’•π’Šπ’‡π’Šπ’„π’Šπ’‚π’ π’Šπ’π’•π’†π’π’π’Šπ’ˆπ’†π’π’„π’† π’„π’π’‚π’”π’”π’Šπ’‡π’Šπ’„π’‚π’•π’Šπ’π’ 𝒐𝒇 𝒓𝒆𝒄𝒕𝒂𝒍 π’π’†π’π’‘π’π’‚π’”π’Šπ’‚ π’ƒπ’š π’†π’π’…π’π’”π’„π’π’‘π’Šπ’„ 𝒇𝒍𝒖𝒐𝒓𝒆𝒔𝒄𝒆𝒏𝒄𝒆 π’‘π’†π’“π’‡π’–π’”π’Šπ’π’ π’‚π’π’‚π’π’šπ’”π’Šπ’”" by @PtrckBlnd et al. in @SciReports classicaproject.eu/2026/02/c… #HorizonEU #AI #colorectalcancer
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What can legal precedents from surgical technology adoption teach us about preserving patient autonomy through informed consent as AI diagnostic and decision-support tools become standard of care? In a Perspective titled, π‘³π’†π’ˆπ’‚π’ π’Šπ’Žπ’‘π’π’Šπ’„π’‚π’•π’Šπ’π’π’” 𝒐𝒇 𝑨𝑰 𝒔𝒕𝒂𝒏𝒅𝒂𝒓𝒅 𝒐𝒇 𝒄𝒂𝒓𝒆 π’Šπ’π’•π’†π’ˆπ’“π’‚π’•π’Šπ’π’ 𝒐𝒏 π’‘π’‚π’•π’Šπ’†π’π’•π’”β€™ π’Šπ’π’‡π’π’“π’Žπ’†π’… 𝒄𝒐𝒏𝒔𝒆𝒏𝒕: 𝒍𝒆𝒔𝒔𝒐𝒏𝒔 π’‡π’“π’π’Ž π’”π’–π’“π’ˆπ’†π’“π’š,Β by Mindy N. Duffourc @MND_Law, Maastricht University and @classicaproject Coordinator Professor Dr @RonanCahill15, @ucddublin, published in @npjDigitalMed, legal cases addressing consent and surgical innovation provide a framework for understanding how AI integration, particularly diagnostic and clinical decision-support tools, will affect the informed consent process and patient autonomy. πŸ‘‰classicaproject.eu/2026/02/c…
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Can AI Measure Surgical Skill? CLASSICA Says Yes. Knowledge Unwrapped: πŸ‡ͺπŸ‡Ί @classicaproject researchers used computer vision to analyse how surgeons place stitches, investigating whether AI can objectively measure suturing quality. Testing three surgical platforms across different experience levels, the team discovered that irregular stitch spacing correlates with weaker sutures. While spatial patterns alone can't fully predict suture strength, this breakthrough moves us closer to intelligent surgical systems that provide real-time feedback during operations, transforming both training and quality assurance. Lead author Professor @albertoarezzo and @unito colleagues just published this pivotal research in Surgical Endoscopy: "π‘­π’“π’π’Ž π’‘π’“π’†π’„π’Šπ’”π’Šπ’π’ 𝒕𝒐 π’”π’•π’“π’†π’π’ˆπ’•π’‰: π’„π’π’Žπ’‘π’–π’•π’†π’“ π’—π’Šπ’”π’Šπ’π’ 𝒇𝒐𝒓 𝒔𝒖𝒕𝒖𝒓𝒆 π’’π’–π’‚π’π’Šπ’•π’š π’‚π’”π’”π’†π’”π’”π’Žπ’†π’π’•β€”π’‚π’ 𝒆𝒙 π’—π’Šπ’—π’ π’‘π’Šπ’π’π’• π’”π’•π’–π’…π’š." Read the open-access paper in Surgical Endoscopy, or our lay summary ⚑: classicaproject.eu/2026/02/k…
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Replying to @classicaproject
I am truly proud of this studyβ€”not only for its results, but for the direction it points to. With this work, we show that computer vision–derived spatial metrics of suturing can be meaningfully linked to real mechanical performance (burst pressure). Spatial features alone are not yet sufficient as standalone predictors of suture qualityβ€”but that is not the main message. The real takeaway is that precision can be quantified, compared, and ultimately automated. This, in my view, is the real turning point for robotic surgeryβ€”including laparoscopic robotics. The future is not about vaguely claiming β€œgreater precision.” The real breakthrough will come when the robot itself is able to plan and execute optimal trajectories autonomously, completing a suture in true task autonomy. Crucially, this autonomy must be human-in-the-loop: the robot operates autonomously, but always under human supervision and control, with the surgeon retaining authority, responsibility, and the ability to intervene at any time. This is not about replacing the surgeonβ€”it is about augmenting human skill with measurable, reproducible precision. This is the approach robotic surgery advocates should take to demonstrate real value in the operating room: β€’quantitative metrics, β€’verifiable automation, β€’objectively demonstrable technical benefits, rather than generic statements about precision. At MITIC-Lab, we believe this circle can close very soon. Within the year, at least in the laboratory setting, we expect to see genuine integration of automated routines into robotic surgical gestures. At that point, the benefit of robotic technology will no longer be a matter of opinion. It will be evidence-based. Research on surgical automation is now becoming truly exciting, concrete, and useful. And this is only the beginning.
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Can spatial metrics of suture placement quantitatively reflect mechanical performance, and how do operator experience and surgical platform influence technical outcomes in minimally invasive surgery? In the @classicaproject publication, authors Roberto Spagnulo, Francesco Marzola, Federica Corso, Giovanni Distefano, Matteo Pescio, Kengo Hayashi, Federica Barontini, Giulio Dagnino, Kaspar Althoefer, Bruno Siciliano, Sebastien Ourselin, and PI Professor @albertoarezzo of the @unito evaluated whether computer vision-derived spatial features of suture placement could predict mechanical strength (measured by burst pressure) across three surgical platforms with surgeons of varying experience levels. While spacing irregularity showed negative correlation with burst pressure, spatial metrics alone proved insufficient as standalone predictors of suture quality, though the approach shows potential for developing real-time feedback systems for surgical training and quality assurance. This paper, π‘­π’“π’π’Ž π’‘π’“π’†π’„π’Šπ’”π’Šπ’π’ 𝒕𝒐 π’”π’•π’“π’†π’π’ˆπ’•π’‰: π’„π’π’Žπ’‘π’–π’•π’†π’“ π’—π’Šπ’”π’Šπ’π’ 𝒇𝒐𝒓 𝒔𝒖𝒕𝒖𝒓𝒆 π’’π’–π’‚π’π’Šπ’•π’š π’‚π’”π’”π’†π’”π’”π’Žπ’†π’π’•β€”π’‚π’ 𝒆𝒙 π’—π’Šπ’—π’ π’‘π’Šπ’π’π’• π’”π’•π’–π’…π’š, was published on December 4, 2025, in Surgical Endoscopy. Read the paper πŸ‘‰link.springer.com/article/10…
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πŸ‡΅πŸ‡Ή Today we meet in the beautiful Porto for day 1 of the @CLASSICAproject plenary meeting. We will open the meeting with discussions on our #AI classifier and results from in-situ endoscopic classification of rectal neoplasia. πŸ”— Check out our recent article in press, π‘¨π’“π’•π’Šπ’‡π’Šπ’„π’Šπ’‚π’ π’Šπ’π’•π’†π’π’π’Šπ’ˆπ’†π’π’„π’† π’„π’π’‚π’”π’”π’Šπ’‡π’Šπ’„π’‚π’•π’Šπ’π’ 𝒐𝒇 𝒓𝒆𝒄𝒕𝒂𝒍 π’π’†π’π’‘π’π’‚π’”π’Šπ’‚ π’ƒπ’š π’†π’π’…π’π’”π’„π’π’‘π’Šπ’„ 𝒇𝒍𝒖𝒐𝒓𝒆𝒔𝒄𝒆𝒏𝒄𝒆 π’‘π’†π’“π’‡π’–π’”π’Šπ’π’ π’‚π’π’‚π’π’šπ’”π’Šπ’” nature.com/articles/s41598-0… @EU_HaDEA #HorizonEU
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#AI is transforming healthcare, but who's liable when it gets a diagnosis wrong? Professor @gerke_sara's @classicaproject research on "nutrition labels" for AI medical devices is sparking crucial conversations in @MedEconomics and beyond about transparency, accountability, and the future of medical malpractice. Read a recap of the recent media flurry ❄️ here: classicaproject.eu/2026/01/p…
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