CD Genomics is aiming at providing the research community with high quality Next Generation Sequencing and Long Read Sequencing services.
Shirley, NY, USA
Joined June 2013
- Tweets1.4K
- Following1.5K
- Followers672
- Likes0
Cancer's circular ecDNA survives via Polθ-mediated MMEJ repair at TA-repeat breakpoints. Block MMEJ (not NHEJ/HR) → selective ecDNA loss → weakened tumors.
Billing et al., Nature 2026. doi.org/10.1038/s41586-026-1…
#ecDNA #CancerResearch #nature
Customer case: the CLK2/SRSF9 splicing axis drives AR-V7 in prostate cancer. Van Goubergen et al. (Mol Oncol 2025) used nanopore sequencing provided by CD Genomics for isoform-resolved transcripts. doi.org/10.1002/1878-0261.13… #LongReadSequencing #CancerGenomics
2 mL plasma, 1–5x WGS. cfDNA fragmentomics reads fragment sizes, end motifs, nucleosome footprints, CNV — a tissue-origin signal beyond mutations.
Full service + pipeline: cd-genomics.com/biomedical-n…
#LiquidBiopsy #cfDNA #NGS
~17% of tumors carry oncogenes on extrachromosomal circles — standard WGS barely sees them. Circle-enriched sequencing + eccDNA bioinformatics. cd-genomics.com/biomedical-n… #eccDNA #NGS #CancerResearch
11,692 genes silenced. 2.5M single cells profiled.
A genome-scale CRISPRi atlas of human iPSCs (Nat Biotechnol, 2026) maps how genotype shapes cell state — data and pipelines fully open.
doi.org/10.1038/s41587-026-0…
#CRISPRi #iPSC
A genome-wide CRISPR screen in haploid hESCs revealed ATF7IP as a suppressor of paternal imprinting (Nat Commun).
RRBS library prep & sequencing for the methylation maps: provided by CD Genomics.
doi.org/10.1038/s41467-021-2…
#CRISPR #Epigenetics
The RNA you want may not be in cells — it's in transit.
Exosomal RNA sequencing: miRNA, mRNA & lncRNA from serum, plasma, urine, or culture supernatant.
cd-genomics.com/exosomal-rna…
#Exosomes #LiquidBiopsy
Pooled CRISPR screens live or die on the readout.
CRISPR screen sequencing + MAGeCK analysis: sgRNA abundance, fold changes, ranked gene hits from 5×10⁶ cells or ≥1.5 μg gDNA.
cd-genomics.com/crispr-scree…
#CRISPR
Pathogenic germline variants raise childhood cancer risk ~12-fold.
Among 75,602 children sequenced before age 3, carriers developed malignancies at 3.23/1,000 person-years. Genes: NF1, TSC2, RB1, WT1.
doi.org/10.1038/s41591-026-0…
#CancerGenetics
How RNA-seq untangled self-compatibility & oil biosynthesis in noug, an underutilized oilseed crop. Authors used RNA sequencing & analysis provided by CD Genomics. 🌱
doi.org/10.1038/s41598-025-1…
#RNASeq #PlantGenomics #CDGenomics
qPCR answers one question. NGS answers the ones you didn't know to ask.
HBV/HPV/EBV capture, tNGS, and 16S profiling for bacteria, viruses, fungi, and parasites.
cd-genomics.com/diseasepanel…
#PathogenSequencing
CD Genomics hereditary cancer panel: 37 genes, amplicon NGS, >1000× depth, SNV/InDel/SV detection.
From 200 ng gDNA — blood, saliva, tissue, or FFPE.
cd-genomics.com/diseasepanel…
#HereditaryCancer #NGS
Rare variant GWAS associations can be confounded by structure, assortative mating, and family effects.
UK Biobank study: doi.org/10.1038/s41467-026-7…
Plant-protein fishmeal replacement alters rainbow trout gut microbiota and astaxanthin pigmentation.
16S/18S/ITS sequencing by CD Genomics: doi.org/10.3390/ijms26241207…
tRNA sequencing decodes full tRNA sequences, modifications, and charging status directly.
CD Genomics: cd-genomics.com/trna-sequenc…
Ribo-seq captures what ribosomes are translating at codon resolution.
CD Genomics end-to-end service: cd-genomics.com/ribosome-pro…
A Nature Communications study on East Asian aspan combines 5 genomes + 222 resequenced trees to map climate adaptation—and maladaptation—using pan-genome + population genomics.
DOI: 10.1038/s41467-026-77788-3
#Genomics #PanGenome
205 avocado trees were whole-genome resequenced to resolve racial ancestry. For library prep and Illumina NovaSeq sequencing, the authors used CD Genomics.
DOI: 10.3390/ijms262110353
#Genomics #CDGenomics
A single reference genome misses accessory genes and structural variants. Pan-genome sequencing captures the full species diversity—core vs. accessory genome—on Illumina, PacBio, or Nanopore.
cd-genomics.com/pop-genomics…
#PanGenome #Genomics #CDGenomics
Xenium systematically benchmarked across 40+ breast & lung tumor sections: per-gene sensitivity varies, off-target signal is real, panel size changes sparsity. Bilous et al., Nat Methods 2026.
doi.org/10.1038/s41592-026-0…
#Xenium #SpatialTranscriptomics