Cognitive Ageing and Impairment Neurosciences Lab, Adelaide University. Led by Prof Tobias Loetscher and Prof Hannah Keage. Views are our own.

Joined June 2016
Mapping connectomes in disease? Check out our article on clinical connectomics in @NeuroCellPress - Tractography behavior in disease - How to measure connectivity - How pathology impacts each stage of connectome mapping - Multiscale connectomics cell.com/neuron/fulltext/S08…
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Aerobic exercise, intensive blood pressure and cholesterol reduction, or both did not show differences in cognitive function improvement over 24 months among older adults with family history of #dementia or subjective #cognitive decline. ja.ma/4v7Jscn
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⭐ META-ANALYSIS: Hospital delirium --> devastating long-term outcomes 253 studies, 137,000+ pts: • 5.4x dementia risk • 2.8x institutionalisation • 2.5x mortality • 1.7x readmission ⚠️ Delirium = a serious acute problem AND a risk warning. ➡️ All pts deserve robust delirium assessment
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🫀What is the relationship between adult cardiorespiratory fitness (CRF) and dementia risk? 🫀 Newly published research in #DADM demonstrate high CRF is longitudinally associated with a lower risk of late-onset dementia (🧵1/2) Full Article: alz-journals.onlinelibrary.w…
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#Delirium is not “just confusion”, it is a major prognostic event in CV medicine. In our State-of-the-Art Review in #EHJ, we synthesize current evidence on mechanisms, prevention, and management across the CV continuum. 🧠🫀 acortar.link/PfFZLf @CekajEndrit et al👏👏
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🔥🔥Exciting news!!!🔥🔥 The invited speaker schedule for the 2026 Noosa Brain Workshop has been finalised! Commuter registrations are still available, but close Feb 1. 3 more weeks to get in!!! Register here: monash.edu/turner-institute/…
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CAIN retweeted
Togo et al. show strong electrophysiological links between the hippocampus and both the anterior and posterior thalamus, along with robust connections between thalamic subregions. tinyurl.com/yw6mccn9; tinyurl.com/bdhh28dn
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Exciting announcement! Our Institute is calling for applications for a EMCR 2-year fellowship . Come and join a great team @turnerinstitute! Details here: careers.pageuppeople.com/513…
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🏆 Nominate now: 2026 PM's Prizes for Science – Australia's most prestigious science awards. 8 prizes spanning STEM innovation, Indigenous knowledge systems & teaching excellence. $50K or $250K + national recognition. Know a deserving scientist or educator? industry.gov.au/PMPrizes #PMprizes
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Yet more evidence that haloperidol is not a sedative. RCT to ⬇️ agitation in palliative care #delirium 1⃣haloperidol 2⃣lorazepam 3⃣halop + loraz 4⃣placebo Haloperidol monotherapy was not more efficacious than placebo in reducing RASS. doi.org/10.1001/jamaoncol.20…
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The VasCog-2-WSO criteria provide updated international guidelines for diagnosing vascular cognitive impairment and #dementia, incorporating recent biomarker advancements. ja.ma/4mU8vtX
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We reassessed the @TheLancet 14 dementia risk factors and added poverty, wealth shocks, income inequality, & HIV. This provides a larger estimation of preventable dementia & exposes gender inequities with larger burdens in women. Out in @eBioMedicine bit.ly/4nU30fU. Great leadership of Cyprian Mostert and congrats all authors: @MomohChi , Andrea Sylvia Winkler, Connor McLaughlin, @HarrisAEyre , @Mohamed03966736, Kirti Ranchod, @DominicTrepel , @vradenburg3 , William Hynes,@FiegsZA , Shehzad Ali, Najat E. L. Mekkaoui, Alan Landay, @dr_bobrow, @levi_muyela, Kelly Atkins, @ChadhaAnt, @r_marongiu, @PaolaBarbato, @sam_nightinga1e, John Joska, Alfred K. Njamnshi, Mie Rizig, @JamesGKahn1, Karen Blackmon, Zul Merali
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2025 ⁦@CAIN_Lab⁩ photo! Although needs Tobias photoshopped in, as he’s overseas.
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New paper in Imaging Neuroscience by Sian Virtue-Griffiths, Nigel C. Rogasch, et al: Task-related changes in aperiodic activity are related to visual working memory capacity independent of event-related potentials and alpha oscillations doi.org/10.1162/IMAG.a.150
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The VasCog-2-WSO criteria provide updated international guidelines for diagnosing vascular cognitive impairment and #dementia, incorporating recent biomarker advancements. ja.ma/4n7oUvT
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Out of 800+ studies on blood-based biomarkers for Alzheimer's, not a single one measured actual changes in patient outcomes. doi.org/10.1136/bmj-2025-084…
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Team Leader: Technical Services position now open! Come work with us on EEG, PSG and VR research studies. The role will support psychology researchers at the new Adelaide University 🧠 lnkd.in/gER7uDqP
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