@BruningLab
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Research lab at the University of Adelaide with a focus on structural biology, protein chemistry, drug discovery, and enzymology
Adelaide, South Australia
Joined July 2018
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Was lucky to meet up with former PhD students from BruningLab: Andrew Marshall (UWA), Andrew Thompson (Oxford/WEHI) and Jordan Pederick (UA)
Congratulations @StephNguyenPhD and good luck on all future protein preps. I’m sure there will be many.
Ayyy the letter has arrived! Ya girl is officially #PhDone A quick moment of celebration in the lab before I get back to my protein prep 🥲 @UniAdelSciences @BruningLab
Congratulations Dan on delivering a great poster! Very well deserved!
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A brand new review written by @FrkicRebecca sheds light on how we can treat type 2 #diabetes by inhibiting PPARy phosphorylation
"The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 #diabetes"
@UniofAdelaide @FrkicRebecca #JBCReviews #drugdesign
qoo.ly/3dmtmj
Some fantastic work from @acmarshallphd from his time in Adelaide
By tweaking this #enzyme in only a handful of places we made it activated by K+ ions… some #proteins are remarkably engineerable! @BruningLab portlandpress.com/biochemj/a…... (1/3)
Bruning Structural Lab retweeted
Latest work from the lab is published
doi.org/10.1002/chem.2021027…
#biocatalysis, #ozchem, #P450s
Lead by Master students Rebecca @RebeccaChao29 and Ian @LordOfSpatulas
@AdelaideChem
@UQ_SCMB
Bruning Structural Lab retweeted
🔥 New advance article for RSC Chemical Biology! 🔥 Andrew Abell, @BruningLab et al @UniofAdelaide exploring a cell permeable bimane-constrained PCNA-interacting #peptide! #chembio #bimane
🧐 Read the #TransparentPeerReview #OpenAccess article 👉ow.ly/6cEG50FIwyp
That’s a wrap for @StephNguyenPhD who gave her completion seminar last week. She’s off to @WEHI_research to continue on her structural biology journey. Best of luck!
It's been an absolute pleasure having you @StephNguyenPhD as a student with the @BruningLab ☺️ Super happy for you!!! @WEHI_research is going to be very lucky to have you!!! 🎉🎉💪💪
@AdelaideProtein @UniAdelSciences
Exciting work coming from @StephNguyenPhD. Read the preprint on @biorxivpreprint!
So excited to be part of this work on #SARSCoV2. Available to read on @biorxivpreprint! biorxiv.org/content/10.1101/…
Bruning Structural Lab retweeted
New work from My lab and collaborators at UQ on understanding the mechanism of stereoselective P450 catalysed epoxidations
pubs.acs.org/doi/10.1021/acs…
#ozchem #P450 @AdelaideChem @UQ_SCMB
A comprehensive review written by @StephNguyenPhD and @TruongJia - an interesting read for #antifungal enthusiasts
Aaand it’s published! I’ve written a review for @FrontMolBioSci with @TruongJia and @BruningLab that discusses exciting and unconventional fungal 🍄 pathways we could be targeting in our search for new #antifungal #drugs 💊
frontiersin.org/article/10.3…
Some fresh #aspergillus research from @StephNguyenPhD published in @FEBSJournal - a tremendous amount of work to elucidate the structural determinants of nucleoside selectivity of the enzyme, nucleoside-diphosphate kinase
My 1st first author paper is out! A paper I’m so proud of because I learnt everything I now know about crystallography from this protein 💎 big thanks to our collaborators @blagojce11 @PukalaLab @BruningLab
onlinelibrary.wiley.com/shar…
Congratulations to @FrkicRebecca on submitting her PhD thesis! Wishing her all the very best for the future 💕
I have just submitted my PhD thesis at @UniofAdelaide! Shout out to those legends who have made my experience amazing. This journey has been so incredible and I am so excited for what is next to come!
A snapshot of some of the exciting projects we have been working on using #proteincrystallography
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A new publication from @StephNguyenPhD from her time in the Booker Lab that started her work on #fungi and #antifungals with Dr. Sternicki and Dr. Polyak. Check it out!
authors.elsevier.com/a/1bUOT…
An insightful review written by @aimeehorsfall from #AbellGroup for anyone interested in #peptidomimetics, cancer therapeutics and #PCNA
Targeting PCNA with #peptidomimetics for therapeutic purposes (@BruningLab @UniofAdelaide) #drugdesign #cancer doi.wiley.com/10.1002/cbic.2…
A Bruning reunion! Always nice to catch up with @acmarshall88, especially at @ITSASBMB!
The latest in #PPARgamma research as we work towards developing improved anti-diabetic drugs
Thanks to @AdelaideProtein I was able to present some of my work at the @ITSASBMB conference in sunny Fremantle today! #ASBMB2019
