@BrownstoneLab

Our work in the lab focuses on brain stem, spinal cord, and spino-muscular circuits for movement.

ucl.ac.uk/ion/neuromuscular-diseases/neural-circuits-movement-laboratory
Joined August 2020
  • Tweets109
  • Following15
  • Followers266
A pre-print that covers many years of work is particularly sweet... great work Amanda!! and thank you to all contributors! biorxiv.org/content/10.1101/… #DYT1 #dystonia #spinalcord

Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction

Dystonia, a neurological disorder defined by abnormal postures and disorganised movements, is thought to be a neural circuit disorder with dysfunction arising within and between multiple brain...

biorxiv.org
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As I'm considering whether or not I have a future on this platform, I thought prospective PhD students might want to look at this tremendous opportunity! opticalbiology.org/apply

Apply — Optical Biology

opticalbiology.org
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Brownstone Lab retweeted
Warren lab@DrWarrenLab4 Nov 2022
Two #postdocposition available focusing on #spinalcordinjury and #regeneration at the @WolfsonCARD @KingsIoPPN, one in @DrWarrenLab one in @BradburyLab Apply before the 22nd of Nov: jobs.kcl.ac.uk/gb/en/job/057… jobs.kcl.ac.uk/gb/en/job/056… #postdocjobs #sciencejob
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Nice work!
This Post is from an account that no longer exists. Learn more
What's the corticospinal tract all about anyway, other than a misleading name? How did it change in evolution? The strengths of comparative neurobiology are shown in the excellent work from the Tuszynski lab, 2 clicks from here! facultyopinions.com/prime/ar…
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Sad news. A superb scientist, outstanding contributions to our understanding of the brain.
MarcoBeatoLab@BeatoLab4 Oct 2022
I just learnt of Philippe Ascher's death. He was the sweetest human being and a great mind. We met often over the last ten years and we always asked each other 'what are Renshaw cells for?' We still don't know, I wish you were still with us
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Great opportunity in amazing, collaborative, collegial environment in the heart of London. Anything life science - from engineering, theoretical, computational, experimental, data, clinical, methodological .... perspective. DM if you have any questions and please RT.
The Francis Crick Institute@TheCrick1 Sep 2022
Come start your group at the Crick! 💡 We're looking for creative researchers from all areas of biology and biomedicine to join our early career faculty community. #AcademicJobs | #ECRChat Learn more and apply by 6 October ⤵️ crick.ac.uk/careers-study/fa…

Early career group leaders

We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

crick.ac.uk
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congrats!!! exciting move!!
Ilary Allodi@AllodiLab19 Aug 2022
📣📣 I am delighted to announce that I will join the @st_psy at University of St Andrews on a permanent lecturer position from January 2023 🤩 So thrilled for this new opportunity in a great environment!
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Brownstone Lab retweeted
MarcoBeatoLab@BeatoLab19 Aug 2022
New methods paper from my lab, more in print at @JNeurophysiol. A simple method, hopefully useful for many. We have already hosted several people who wanted to learn to record from mature spinal cord preps. Get in touch if you want to implement the method
JNP@JNeurophysiol18 Aug 2022
In vitro longitudinal lumbar #SpinalCord preparations to study sensory and recurrent motor #microcircuits of juvenile mice **new in #JNeurophysiol ow.ly/HqGQ50Kkf53 @juliOjedaAlonso #ArticlesInPress #MotorControl #neuroscience
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This is an eye opener
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This is definitely an exciting opportunity to join a great department in a beautiful city! employment.ku.dk/faculty/?sh…
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Brownstone Lab retweeted
MarcoBeatoLab@BeatoLab18 Jul 2022
Latest multi-lab effort to understand segregation of flexor-extensor premotor interneurons. @BrownstoneLab, @ZampieriNiccolo, @RemiRonzano, @spinalcordgroup and now also Sam Pfaff. Summary: we can't get no segregation. And we tried biorxiv.org/content/10.1101/…

Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled

Elaborate behaviours are produced by tightly controlled flexor-extensor motor neuron activation patterns. Motor neurons are regulated by a network of interneurons within the spinal cord, but the...

biorxiv.org
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Brownstone Lab retweeted
MarcoBeatoLab@BeatoLab22 Jul 2022
Such a neat figure highlighting such a common mistake (that I have done several times in the past). Editors and reviewers out there, please do take note rupress.org/jcb/article-pdf/…
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Great to see this on BioRXiv, great work @CalvinChad_ ! Kv2 conductances are not required for C-bouton mediated enhancement of motoneuron output biorxiv.org/content/10.1101/…

Kv2 conductances are not required for C-bouton mediated enhancement of motoneuron output

Neural motor systems have evolved complex circuits that afford animals a range of behaviours essential for survival. C-bouton synapses arising from cholinergic V0C interneurons amplify motoneuron...

biorxiv.org
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It looks like #IMNS2022 is really going to happen. See you soon for a great conference where we will see good friends and learn a lot about MN physiology and genetics, #MotorNeuroneDisease #ALS and more. Program looks great, thank you @MGorassini and team! See you in #Banff !!
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Simply incredible! @lifeafterpara Chair of Trustees, Richard Tolkien & crew, with sailing boat Rosalba, have officially broken the Bermuda-Plymouth world record as confirmed by the World Speed Sailing Record Council!🙌 Learn more👉 lifeafterparalysis.com/Blog/… @TheDailySail

Rosalba Atlantic, Bermuda to Plymouth World Record Broken - Blog

Read about the highs and lows aboard Rosalba, as our Chairman, Richard Tolkien and crew, Bronwen Maddox, Frank Sturm and David Herrod attempted to break the world record for crossing the Atlantic...

lifeafterparalysis.com
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Check out our website for program, abstracts, and updated info for #IMNS2022 - see you in Banff soon!
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Three more weeks to apply to join a great team
Andreas Schaefer@AndreasTSchafer16 Mar 2022
Neurosurgeons - exciting collaboration with @hani_marcus @hugo_lh @WRMuirhead and colleagues from NHNN - please RT
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Exciting postdoc position for a multi-photon enthusiast working with @petrzzz, @Flor_Iacaruso and myself @TheCrick - please RT tinyurl.com/3pAtCrick
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Brownstone Lab retweeted
MarcoBeatoLab@BeatoLab26 Apr 2022
New paper from the lab on BioRxiv. No hype, no overselling! It is just a simple methods paper, showing motoneuron recordings from semi intact, mature, spinal cord preparations, preserving afferent or efferent circuits. biorxiv.org/content/10.1101/…

In vitro longitudinal lumbar spinal cord preparations to study sensory and recurrent motor microc...

In vitro spinal cord preparations have been extensively used to study microcircuits involved in the control of movement. By allowing precise control of experimental conditions coupled with state-of...

biorxiv.org
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