“I ❤️ Cholesterol; but my ❤️ doesn’t” However, there’s much much more to cholesterol than that. We study how we and our cells balance this Jekyll/Hyde molecule
Sydney, New South Wales
Joined September 2018
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Brown Lab UNSW retweeted
One of the best things about science is speculating on how to solve a fascinating problem.
Check out our paper "A paREDOX in the control of cholesterol biosynthesis" in #BioEssays.
doi.org/10.1002/bies.2024000…
@UNSWScience @UNSWBABS (1/3)
Brown Lab UNSW retweeted
Thrilled to have the final pieces of my PhD work with @BrownLabUNSW published in @jbiolchem - huge thanks go to @TinaBNguy for the effort to get it across the line after my departure for the UK, and also to @ximingDu for the beautiful microscopy! (🧵1/4) doi.org/10.1016/j.jbc.2024.1…
Brown Lab UNSW retweeted
Very excited to uncover SC5D as the 6th cholesterol synthesis enzyme targeted by our favourite E3 ligase MARCHF6! Check out our findings in
@BBAjournals
doi.org/10.1016/j.bbalip.202…
@UNSWScience
Brown Lab UNSW retweeted
CO2, regulation and metabolism. @NicoleMFenton @BrownLabUNSW explore a #PLOSBiology study that provides the first link between #CarbonDioxide and the master transcriptional regulator of #cholesterol homeostasis. Paper: plos.io/3QEDs7f Primer: plos.io/46sLSV2
Brown Lab UNSW retweeted
Great way to end the year with my first first-author publication - a mini-review looking at the interplay between sugar and cholesterol metabolism. @UNSWScience🧵(1/3)
sciencedirect.com/science/ar…
Brown Lab UNSW retweeted
A big milestone today with @BrownLabUNSW celebrating 20 years with @UNSWScience !!!
It is amazing to think how many young researchers have walked through the lab and emerged as actual real life scientists thanks to Andrew's mentoring and guidance.
Brown Lab UNSW retweeted
A molecule first found in sharks over 100 years ago has been found to regulate a key enzyme in the production of #cholesterol—offering potential for the development of new #cholesterol-lowering drugs. #CVD newsroom.unsw.edu.au/news/sc…
Brown Lab UNSW retweeted
It's finally done! My first 1st author paper has finally been published where we identified 2 new substrates for the E3 ubiquitin ligase MARCH6 in the cholesterol synthesis pathway. Thanks @BrownLabUNSW for all of the support. #AcademicTwitter
portlandpress.com/biochemj/a…
Brown Lab UNSW retweeted
Nothing gets me in the Christmas Spirit more than re-submitting my first 1st author paper! Fingers crossed for acceptance.
Pictured: about 25 draft versions of this manuscript that I found on my desk as I cleaner it up
#phdchat #AcademicTwitter #AcademicChatter
Brown Lab UNSW retweeted
When lab friends become real friends. Thanks for the catchup this morning! @DrWinnieL, @prabhuanika and @DrVickyHowe, all previous members of @BrownLabUNSW! – at Sydney, New South Wales
Brown Lab UNSW retweeted
A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase.
This costume-themed commentary on an October #ResearchHighlight comes to us from @BrownLabUNSW + @hudsonwilco . You can read it here: ow.ly/Gczr50wAqD9
Brown Lab UNSW retweeted
The @jbiolchem is awesome. Over years, I've published >30 papers there. Careful reviews with attention to science not sexiness. Arthur Kornberg reminded me once that Nature and Science are magazines, not journals. If a student with JBC papers applies to us, we pay attention.
As discussed most of our GLP-1 findings over the years were rejected by "high impact" Journals. This paper describing GLP-1 inhibition of apoptosis is now featured @jbiolchem after 700+ citations. Don't let glam Journals define you jbc.org/content/294/34/12622…
Brown Lab UNSW retweeted
My lab's blog got featured by LabArchives! Nice to know we're appreciated 😁.
Thanks for enjoying our #blog @LabArchives!
@UNSWScience @BrownLabUNSW
blog.labarchives.com/2019/08… – at Sydney, New South Wales
Brown Lab UNSW retweeted
I never feel like I can tweet effectively, but I have to let the world know I got the most exciting results of my PhD so far last Friday! What a good day to be me
#phdchat #wetlab #AcademicChatter @BrownLabUNSW
Brown Lab UNSW retweeted
Super grateful to receive this award - thanks to the organisers of #acmm19 for a brilliant conference! Plenty of very exciting work in the field.
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Brown Lab UNSW retweeted
How a rate-limiting enzyme in cholesterol synthesis is degraded in response to cholesterol bit.ly/2JRT8Ds #lipids #openaccess
Brown Lab UNSW retweeted
The development of new, cholesterol-lowering drugs could be on the cards, with @UNSW scientists discovering how a key enzyme of cholesterol production can be regulated – and destroyed – using a particular molecule. @mediocre_jake @BrownLabUNSW. newsroom.unsw.edu.au/news/sc…
Brown Lab UNSW retweeted
Andrew Brown and colleagues highlight two recent squalene epoxidase papers from Agios Pharmaceuticals scientists.
@BrownLabUNSW @AgiosPharma @mediocre_jake
go.nature.com/2VnZahw
Brown Lab UNSW retweeted
Super excited to be learning a new technique - GC/MS! Just a few weeks into my #PhD and I feel like I’ve already *peak*ed #research #massspec #academictwitter #phdchat @UNSWScience
