@BremnerRod

Scientist at LTRI, Mt Sinai, Pan-cancer features, Drug resistance, RB, Retinal Development & Regeneration

 Toronto, Ontario
Joined October 2019
  • Tweets110
  • Following158
  • Followers180
8Media
Sinai Health researchers have developed an “immune cloaking” technology that protects transplants from rejection in unmatched hosts in a bid to eliminate the need for immunosuppressive drugs in transplant patients. bit.ly/3QS7g0h #ltriresearch #regenmed #celltherapy
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Deneddylation of ribosomal prots ->Potent in vivo synergy w standard of care (complete responses). Crispr screens ->mech. Less DNA damage but more cell death led by RPs leaving nucleolus. No tox in vivo. Same Mech in retinoblastoma & multiple myeloma. cell.com/cell-reports/pdfExt…
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Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses dlvr.it/StTXFW

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit...

Prior studies with MLN4924/Pevonedistat attribute efficacy in cancer treatment to inhibition of cullin neddylation. Aubry et al. show that blocking ribosomal protein neddylation underpins MLN4924...

cell.com
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Join us! A great environment for your graduate studies!
IRCM@ircm_mtl3 Jan 2023
Be part of the excellence in biomedical research. Submit your application now for the molecular and cellular medicine Master’s degree! #DrivenByLife ircm.qc.ca/en/m-sc-molecular…
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Special Topic issue that I help co-edit with R. Poché, @SethBlackshaw @MurielPerron @ThomasReh4 and V. Wallace now available. Check it out! Retinal Regenerative Medicine Strategies for Vision Preservation and Restoration frontiersin.org/research-top…

Retinal Regenerative Medicine Strategies for Vision Preservation and Restoration

Retinal degenerative diseases and traumatic injury result in permanent loss of retinal neurons and thus sight, depriving many worldwide of one of our most valued senses. Due to the clinical need for...

frontiersin.org
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Replying to @philmcdonald94 @RTG_Podcast
No matter what the thoughts are on Stewart’s ability as Captain and defender, there is no place for this behaviour. It belongs in the prehistoric era.
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Aberdeen captain Anthony Stewart posting on Instagram to say that he’s suffered racist abuse following last weekend’s game against St Mirren.
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Rod Bremner retweeted
Julien Sage@SageJulien23 Dec 2022
New work from Jun Kim and Julie Ko @kojulieh in the lab on the atypical Notch ligand DLL3, a 🌶️ 🔥 immunotherapy target in neuroendocrine tumors, including SCLC sciencedirect.com/science/ar…
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Canada is just not a serious scientific country. We had such hope under @JustinTrudeau @cafreeland but alas here we are...
Brad Wouters 🇨🇦@bradwouters21 Dec 2022
The $2.5B NIH increase is 2.8X the entire CIHR budget. Total NIH ($47.5B) is 54X the entire CIHR budget - 6X per capita. Canada needs to double tri-council budgets now and build a long term strategy for systematic investments. science.org/content/article/…

Research gets a boost in final 2023 spending agreement

Budgets of many civilian science agencies will grow, but not always by as much as White House had requested

science.org
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The $2.5B NIH increase is 2.8X the entire CIHR budget. Total NIH ($47.5B) is 54X the entire CIHR budget - 6X per capita. Canada needs to double tri-council budgets now and build a long term strategy for systematic investments. science.org/content/article/…

Research gets a boost in final 2023 spending agreement

Budgets of many civilian science agencies will grow, but not always by as much as White House had requested

science.org
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Qatar, great world cup. Yay, money buys a lot. But it doesn’t hide your bigotry, slavery, and homophobia. None of those are culturally acceptable. Just treat human beings with respect. Simple.
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The Goodman is an impressive institute. Amazing trainees. Talented and fun. Montreal rocks!
Thomas Duchaine@thomas_duchaine18 Nov 2022
Replying to @gcss_gci
A huge THANK YOU! To the GCSS leaders and organizers and the the GCI support team for a splendid day of exciting science! Thank you @BremnerRod for joining our community for one day and for a great Keynote.
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Qatar needs to stop going all medieval on LGBT+. Tell FIFA to use world cup to urge then to change their barbaric stance. Sign the petition.. action.allout.org/en/m/b050d…
Qatar and Wales - both ~3M population Wales worker deaths 11 PER YEAR Qatar migrant worker deaths since awarded world cup: ~12 PER WEEK. 650 per year. 6500 in ten yrs. FIFA: speak out louder please. Like the Australians just did:
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With Boris humpty dumpty Johnson now looking to get it back together again, I’m warmed by his old pal turned back stabber Dominic Cummings characterization of BJ as a « complete fuckwit » theguardian.com/politics/202…

Fines, lies and chaos: a reminder of Boris Johnson’s time as PM

As former prime minister expected to run again, a recap on what living under Johnson was like

theguardian.com
This is important everyone. Check it out!
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Retinal alpha-cre transgene users. Insert site mapped. Useful for genotyping. Site is amid olfactory enhancers, so Cre also expressed in olfactory. rdcu.be/cMArp
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Rod Bremner retweeted
CIHR
@CIHR_IRSC11 Mar 2022
We welcome the recent statement by Minister Champagne and Minister Duclos calling for measures to support Ukrainian research personnel in their time of need. Read the statement from the presidents of Canada’s federal research granting agencies: science.gc.ca/eic/site/063.n…
Canadian Science
@CDNScience11 Mar 2022
Today, Minister Champagne and Minister Duclos condemned the invasion of #Ukraine and expressed support for Ukrainian researchers. ow.ly/yYtm50IhbBs #CanadaSupportsScience #StandWithUkraine
Statement

ALT Statement

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Are you interested in Stem Cells, Cancer and Development? Check out this meeting! Great line-up of speakers and as a bonus: It's in Lyon, France, in May! stemcellmeeting.sciencesconf…
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This promise to be an exciting line up of speakers. It will be held in hybrid format, so register to attend!
IRCM@ircm_mtl22 Feb 2022
Don't miss our first ECS3 Seminar next week: a groundbreaking initiative whose mission is to showcase early career scientists and a great opportunity to discover the exciting projects of researchers in training ircm.qc.ca/en/events-details… #DrivenByLife
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