@BrandesLab
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Official twitter account of the Institute for Cardiovascular Physiology | Goethe University Frankfurt am Main | @goetheuni | Director: @Ralf_P_Brandes
Frankfurt am Main
Joined March 2022
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Check out the new preprint from the lab in collaboration with @TheMarcelSchulz on calling RNA-DNA interactions from linker-based sequencing methods! biorxiv.org/content/10.1101/…
Do you want to detect #RNA-#DNA interactions from RADICL-seq, Red-C or GRID-seq, but lack a reliable method? Then try RADIAnT, our new statistical framework for calling robust, consistent interactions from RNA-DNA ligation methods biorxiv.org/content/10.1101/…
Institute for Cardiovascular Physiology retweeted
@EVanNostrandLab dive into the new mysteries of snoRNAs in this exciting article.
Includes:
-chimeric eCLiP to map snoRNA-target RNA interactions
- SNORD89 guided 2'-O methylation of U2 leading to splicing regulation
- SNORD3-rRNA processing
biorxiv.org/content/10.1101/…
👏👏👏👏👏
Did you know that there is a second glutamine metabolism pathway that generates α-ketoglutarate?
Check out our new pre-print from @FlaviaRezendeF describing the pathway, now on bioRxiv: biorxiv.org/content/10.1101/…
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This reaction is catalyzed by the ω-amidase enzyme NIT2, which we demonstrate to be a metabolic switch and redox target of oxidative stress.
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If you're interested in exploring this pathway, we can help! Reach out and let us know!
Thanks to all supporting authors @PedroMalacarne1 @tim_warwick @TheMarcelSchulz @Ralf_Gilsbach @fleming_ivs + many more & funding bodies @SFB1531 @CPI_ExStra @dfg_public @goetheuni
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Congrats to @LisaM_Weiss for winning a #DPG2023 poster prize 🎉 – at Frankfurt on the Main, Germany
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Institute for Cardiovascular Physiology retweeted
For anybody at #ISMBECCB2023 interested in mechanisms of regulatory #RNA, I’ll be giving a talk on our recently published method on prediction of RNA-DNA interactions at 12:20 TODAY in the iRNA session! @BrandesLab @TheMarcelSchulz @trr267 @CPI_ExStra – at Lyon, France
Institute for Cardiovascular Physiology retweeted
Come and see our science in 4 talks over the next three days at #ISMBECCB2023 in #Lyon @dzhk_germany @CPI_ExStra @InstCardReg_FFM
Institute for Cardiovascular Physiology retweeted
Delighted to have been given the opportunity by the @RNASociety to present my work at #RNA23 #RNA2023 in #Singapore. Had great discussions about #lncRNA regulation of #chromatin complexes in #endothelial #gene #expression.
@RNASociety @jrRNAscientists @BrandesLab – at Singapore
We’re at the #DGKJahrestagung 2023 in #Mannheim today! We’ve already given some exciting talks including the presentation by @Ralf_P_Brandes for the @SFB1531 and the presentation by Frederike Boos on the #lncRNA LINC00607 in #angiogenesis. – at Mannheim, Germany
We were thrilled to celebrate Matthias Leisegang's successful habilitation last month, where he gave a great Antrittsvorlesung on #lncRNA in the #cardiovascular system. Thanks to @goetheuni , @CPI_ExStra , @trr267, @dzhk_germany and @UK_Frankfurt for supporting Matthias' work! – at Frankfurt on the Main, Germany
Institute for Cardiovascular Physiology retweeted
Yesterday we celebrated the launch of our Integrated Research Training Group.🥳 A successful meeting with highly motivated PhD students, great talks, interesting discussions and tasty food. We are looking forward to many exciting years of CRC-specific training! #letsgetstarted
We’ve just published another #endothelial #lncRNA paper in @BasicResCardiol. LINC00607 maintains ERG target gene transcription by interacting with BRG1 to mediate #angiogenesis. Fantastic work from the team! Very well done! 👏🏻 🎉
link.springer.com/article/10…
Well done to Frederike Boos @JamesAOo7 @tim_warwick @maduiixeta @MelinaL24 @Bibli_lab @GiuliaKarolin @Hinkel_Lab @bakergroupcvs @reinier_boon @TheMarcelSchulz @Ralf_P_Brandes and everyone else who was involved in the project!
Thanks to @goetheuni @dfg_public @CPI_ExStra @trr267 @TheBHF @dzhk_germany and others for supporting the project.
Institute for Cardiovascular Physiology retweeted
Looking forward to our SFB 1531 seminar next Tuesday! Save the date and don`t miss @rooij_laura from CeMM talking about #endothelial cell heterogeneity! #cardiotwitter @goetheuni @CeMM_News
We can’t wait to see so many friendly faces! Plus, our very own @FlaviaRezendeF will be presenting her work on endothelial glutamine metabolism 🧫🧪
27 January 2023 4 - 6 pm @ University Hospital Frankfurt
First joint meeting for basic and clinical heart, kidney and vessel researchers in #Frankfurt to get to know cross-disciplinary topics and methods @BrandesLab @InstCardReg_FFM @IVS_FFM @m_leistner
Our third #lncRNA paper of the month is out! Terrific work from @JamesAOo7 and the team on such a detailed characterisation of PCAT19 function in #endothelial cells 🧬 with the bonus of some great collaborations as well 🤝
🚨Our paper on the role of #lncRNA PCAT19 in #endothelial quiescence, and its implications for #cardiovascular disease, has just been published in @CellReports! 🎉 Featured on cell.com/cell-reports/fullte….
#RNA #vascular @CellPressNews #DNA #ScienceTwitter
@BrandesLab ate Mexican food and drank tequila last night to celebrate three recent #lncRNA publications!
pubmed.ncbi.nlm.nih.gov/3623…
nature.com/articles/s41467-0…
(And the 3rd will be hot off the press next week - watch this space!)
