Clinical Surveillance | Infection Prevention | Pharmacogenomics | Precision Medicine | Healthcare Analytics
Joined July 2012
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🦠 The global rise of metallo-β-lactamase (MBL) producers is challenging treatment of resistant Gram-negative infections. New review highlights shifting epidemiology, diagnostic needs & emerging therapies. 🔬
academic.oup.com/jacamr/arti…
(1/3) Fast disease surveillance relies on two critical steps: 1. DETECTING CLINICAL OUTLIERS INSTANTLY.
🔗 reuters.com/business/healthc…
(2/3) Fast disease surveillance relies on two critical steps: 2. DELIVERING SEAMLESS ELECTRONIC REPORTING TO PUBLIC HEALTH BODIES.
🔗 reuters.com/business/healthc…
(3/3) When unexpected health events occur, automated CDSS workflows help IPs shift from manual data entry to immediate outbreak response.
🔗 reuters.com/business/healthc…
🦠 GOT PHAGES? A new consensus guideline for personalized bacteriophage therapy (endorsed by IDSA) offers >60 recommendations for bringing phage therapy into clinical practice. doi.org/10.1038/s41591-026-0…
#PhageTherapy #AntimicrobialStewardship #AMR #InfectiousDiseases
🦠 New research reveals how a gene related to antibiotic resistance can help C. difficile restore spore formation despite cephamycin antibiotics. Understanding these mechanisms may inform future infection prevention strategies. doi.org/10.1038/s41467-026-7…
🧪 Does delafloxacin offer an edge when Enterobacterales are already ciprofloxacin-resistant? In this study, all 129 isolates were DFX-resistant or above ECOFFs, suggesting little added value from routine DFX testing. doi.org/10.3390/antibiotics1…
Simple steps like auto-reminders for docs & empowering nurses to remove unnecessary catheters can significantly reduce CAUTIs. Yet many hospitals still haven't embedded them into daily care. Key insights via @UofMHealth:
michiganmedicine.org/health-…
#CAUTI #Infectioncontrol #Catheter
International Infection Prevention Week is right around the corner (Oct 19–25)! From Florence Nightingale to real-time analytics, IP has had quite the glow-up. Can't wait to celebrate all the amazing IPs keeping our healthcare spaces safe! 🔗 infectionpreventionandyou.or…
#IIPW #APIC
🦠 Candida in respiratory cultures: colonization, not an automatic call for antifungals. In 548 hospitalized adults, antifungal therapy was not associated with lower 30- or 90-day mortality. Stewardship matters. doi.org/10.1093/ofid/ofag550
CDC has streamlined return-to-work guidance for healthcare personnel with respiratory viruses, outlining when staff can safely return and recommended source control afterward. A useful update for IP and occupational health teams.
cdc.gov/infection-control/hc…
💊 Broader isn’t always better. A new network meta-analysis found ceftriaxone had comparable clinical efficacy to broader agents for cUTI in stable adults—supporting stewardship when local resistance and patient risk factors allow. 🔎 doi.org/10.1093/ofid/ofag592
Hand hygiene is vital, but automated data proves it's not a silver bullet for MDROs.
To move the needle, hospitals need intelligent CDS for early detection, local epidemiology, and fast de-escalation.
cidrap.umn.edu/healthcare-as…
#CIDRAP #MDRO
💊 Gabapentin started inpatient may not stay inpatient. In 464 patients, 63.4% continued at discharge and 83.4% received opioids concurrently. A reminder to reassess indication, safety, and duration at transitions of care. doi.org/10.1093/ajhp/zxac140
Could biosurfactants help prevent healthcare-associated biofilms? 🦠 A new review explores their potential to reduce microbial adhesion, disrupt biofilms, and complement existing infection-prevention strategies. mdpi.com/2076-2607/14/4/910
🫀 Anticoagulation in AF with intermediate stroke risk? The SINGLE-AF trial found DOAC therapy reduced the 24-month composite of stroke, systemic embolism, major bleeding or CV death vs. no anticoagulation (0.5% vs 1.5%). #MedTwitter #Cardiology nejm.org/doi/full/10.1056/NE…
A new study published in JAMA evaluated >190K pts found nearly 1/3 testing positive for Lyme disease antibodies were also co-positive for other tick-borne pathogens like Babesia or Anaplasma. Co-exposure is highest in the Northeast (31.1%).
prnewswire.com/news-releases…
Essential reading: A joint multisociety paper in Clinical Infectious Diseases highlights sepsis strategies:
• Rapid blood cultures + stewardship
• Smart CDS for fast treatment
• Metrics for undertreatment & overexposure
Read more here: idsociety.org/news--publicat…
#Sepsis
🦠 Broad-spectrum ≠ always better. A BALANCE sub-study found anti-anaerobic ABX exposure was associated with +90-day mortality & gut anaerobe depletion in bloodstream infection. Another reminder to use anaerobic coverage only when clinically indicated. doi.org/10.1093/cid/ciag460
🐾 World Rabies Day is Sept. 28. The CDC reports an increase in human rabies exposures and PEP errors. A timely reminder for healthcare teams to review exposure assessment, wound care & PEP protocols.
cdc.gov/han/php/notices/han0…
