I build AI for precision medicine, then lead the teams that scale them. 20+ yrs: genomics → pharma → agentic AI. I write at https://xitter.cf/t.co/22WtM0o2rh and https://xitter.cf/t.co/ht7tYImQXv

Washington, DC
Joined April 2009
Justin H. Johnson retweeted
Today we're open-sourcing Bumblebee, a read-only scanner for macOS and Linux. It checks developer machines for risky packages, extensions, and AI tool configs. Connected to Computer, it can trigger deeper scans whenever a new supply-chain risk emerges. github.com/perplexityai/bumb…
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Justin H. Johnson retweeted
A big day for multi-agent AI to accelerate biomedical discovery, hypothesis generation, designing experiments with proof points of new candidate drugs (cancer, fibrosis, macular degeneration, antimicrobial resistance, and more) 2 @Nature reports @GoogleDeepMind @FutureHouseSF nature.com/articles/s41586-0… nature.com/articles/s41586-0…
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Justin H. Johnson retweeted
Excited to launch Gemma 4: the best open models in the world for their respective sizes. Available in 4 sizes that can be fine-tuned for your specific task: 31B dense for great raw performance, 26B MoE for low latency, and effective 2B & 4B for edge device use - happy building!
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Justin H. Johnson retweeted
OpenAI shipped 6 GPT-5 models in 7 months. Anthropic shipped 2. This isn't iteration—it's weaponized velocity. The strategy: fragment the market, force quarterly re-evaluation, make competitors look slow. Both are good enough now. The battleground is workflow, not benchmarks.
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Justin H. Johnson retweeted
MedGemma 1.5 is a major upgrade to our open models for healthcare developers. The new 4B model enables developers to build applications that natively interpret full 3D scans (CTs, MRIs) with high efficiency - a first, we believe, for an open medical generalist model. MedGemma 1.5 also pairs well with MedASR, our speech-to-text model fine-tuned for highly accurate medical dictation. Developers can now use these multimodal capabilities to build medical apps that reach patients in more places.
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Justin H. Johnson retweeted
Claude
@claudeaiJan 12
Introducing Cowork: Claude Code for the rest of your work. Cowork lets you complete non-technical tasks much like how developers use Claude Code.
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Justin H. Johnson retweeted
If 2025 was beginning of agents, 2026 will be around Agent Harnesses. An Agent Harness is the infrastructure that wraps around an AI model to manage long-running tasks. It is not the agent itself. It operates at a higher level than agent frameworks. The harness provides prompt presets, opinionated handling for tool calls (Human in the loop), lifecycle hooks or ready-to-use capabilities like planning, filesystem access or sub-agent management. As Benchmarks are going to become more complex we need to bridge the gap between benchmark claims and user experience. A Agent Harness can be essential for three critical reasons: - Validating Real-World Progress: Allows users to easily test and compare how the latest models perform against their use cases and constraints. - Empowering User Experience: Without a harness, the user's experience might be behind the model's potential. - Hill Climbing via Real-World Feedback: A shared, stable environment (Harness) creates a feedback loop where researchers can iterate and improve ("hill climb") based on actual user adoption. We are heading toward a convergence of training and inference environments. We see a new bottleneck being context durability. The Harness will become the primary tool for solving "model drift”. Read my full blog 🔽
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Justin H. Johnson retweeted
vLLM just got a major upgrade! Originally built for autoregressive text-based LLM serving, vLLM-Omni now lets you serve text, image, video, and audio models - all from a single framework. You can also serve diffusion models for fast parallel generation. 100% open-source.
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Justin H. Johnson retweeted
ollama
@ollama4 Sep 2025
Meet Google's new best small embedding model, EmbeddingGemma It's a 300M embedding model made for retrieval augmented generation (RAG) use cases. ollama pull embeddinggemma 🧵
🤝 We teamed up with @ollama and llama.cpp to accelerate @googleaidevs' EmbeddingGemma3 for hyper-efficient RAG on PC. Try it out now with @NVIDIA_AI_PC RTX AI PCs and workstations 👇
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Justin H. Johnson retweeted
Greg Brockman
@gdb22 Aug 2025
Our custom LLM, gpt-4b micro, has helped achieve an advance in biology. It designed novel variants of the Nobel-winning Yamanaka factors that achieve a 50x increase in reprogramming efficiency in vitro compared to standard OSKM proteins.
At @OpenAI, we believe that AI can accelerate science and drug discovery. An exciting example is our work with @RetroBiosciences, where a custom model designed improved variants of the Nobel-prize winning Yamanaka proteins. Today we published a closer look at the breakthrough. ⬇️
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Justin H. Johnson retweeted
🌱 Paper Finder is a step toward a fully agentic scientific assistant. Join us on the journey. 💬 Discuss on Discord: discord.gg/SyY85E97M5 📚 Learn more about Paper Finder: allenai.org/blog/paper-finde… 💻 Code: github.com/allenai/asta-pape…
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Justin H. Johnson retweeted
ollama
@ollama14 Aug 2025
ollama run gemma3:270m Gemma 3 270M is here! Small model that is extremely efficient to run on-device, and designed for fine-tuning to serve specific agentic use-cases!
Introducing Gemma 3 270M! 🚀 It sets a new standard for instruction-following in compact models, while being extremely efficient for specialized tasks. developers.googleblog.com/en…
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Justin H. Johnson retweeted
Horizon Alpha just appeared on @openrouter, the THIRD mystery model in their stealth series. Early tests show it's creating full working games in seconds, hitting 130 tokens per second Here's what we know so far: 🧵
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Justin H. Johnson retweeted
9 out of the 10 fastest-growing LLMs this week are open-source
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Justin H. Johnson retweeted
Imagine controlling your devices with a subtle hand or finger gesture. Our cutting-edge research turns intent and muscle signals into seamless computer control. This breakthrough wrist technology is redefining how we interact with computers—intuitive, precise, and ready for the future.
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Justin H. Johnson retweeted
When you realize that open-source is at the frontier of AI despite: - less GPUs - less money - less public and policy support - no $100M salaries to attract talent - with closed-source taking advantage and copying all the innovations of open-source without contributing back theirs 🤯🤯🤯 And we’re just getting started!
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Justin H. Johnson retweeted
Wait so Alibaba Qwen has just released ANOTHER model?? Qwen3-Coder is simply one of the best coding model we've ever seen. → Still 100% open source → Up to 1M context window 🔥 → 35B active parameters → Same performance as Sonnet 4 They're releasing a CLI tool as well ↓
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Justin H. Johnson retweeted
Today, we're announcing a preview of ARC-AGI-3, the Interactive Reasoning Benchmark with the widest gap between easy for humans and hard for AI We’re releasing: * 3 games (environments) * $10K agent contest * AI agents API Starting scores - Frontier AI: 0%, Humans: 100%
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Justin H. Johnson retweeted
Just added switchpoint.dev, a new type of model router that automatically picks the best model and charges users a flat rate for inference. How it works 👇
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