Benedetta Conte (@BenedettaConte5) header
Benedetta Conte (@BenedettaConte5) profile picture

Oncologist & researcher at Università del Piemonte Orientale Marie-Curie PhD fellow

Novara, Italy
Joined October 2018
Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)Photo by Benedetta Conte (@BenedettaConte5)
La dott.ssa @BenedettaConte5, oncologa e docente @UniAvogadro, ha ottenuto un finanziamento @AIRC_it per il progetto NEOMET Lo studio valuterà omega-3 e attività fisica sull’efficacia delle terapie nel tumore al seno Complimenti a Benedetta e al team della Prof.ssa @ALEDIGNUS12
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Out in #ClinicalCancerResearch the results of the TATEN trial in HR+/HER2- mBC post-CDK4/6i. Non-luminal, highly proliferative, immune-enriched tumors showed >24m PFS with pembrolizumab maintenance. Article here: lnkd.in/eYASVuaT @SOLTI #cancerresearch
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Super @fara_bm and colleagues!!!!
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Benedetta Conte retweeted
Hi from Vienna! If you are in the city, join us tomorrow at @IMPvienna for the "Metastasis mechanisms workshop" with @johannes_zuber @JulianeScience @MomoBentires and @BMaierLab
📢The Evomet network will meet soon in Vienna for the 4th Annual meeting, hosted by @IMPvienna and @Boehringer 👉If you are in Vienna, join us for the "Metastasis mechanisms workshop"! Amazing speakers lined-up! 🗣️ @johannes_zuber @JulianeScience @MomoBentires @BMaierLab
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I never imagined how fulfilling this would be. Thrilled to announce that our #DEFINITIVEtrial now has an NCT number: NCT06446882. First SIV this summer! 🔗Link clinicaltrials.gov/study/NCT…
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Great discussion by dr Krop @Yale: here the new algorithm for the management of hormone receptor-positive/HER2-negative advanced #BreastCancer after #ASCO24 @OncoAlert
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Benedetta Conte retweeted
At #ASCO24 @matteolambe presents analysis on BRCA BCY Collaboration including young BRCA carriers affected by eBC: ➡️ Different clinical behavior between BRCA1 and 2 carriers ➡️ Early identification of carriers can lead to improvement in prognosis @OncoAlert @UniGenova
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Benedetta Conte retweeted
Patient-level meta-analysis shows HER2DX is associated with survival outcomes in patients with early-stage HER2+ BC presented by @G_Villacampa #ESMOBreast24 @OncoAlert #bcsm
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#ESMOBreast24 key takeaways @lab_kok Wishlist includes #HER2DX and the development of thedefinitivetrial.eu to achieve better outcomes #precisiononcology #breastcancer
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Super importante conference! Do not miss it!! ⬇️⬇️⬇️⬇️⬇️
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Benedetta Conte retweeted
Why was IMpassion132 negative? And what’s the path forward for improving outcomes in early recurrent TNBC? Great discussion by Sara Tolaney (@stolaney1), recapitulating the current status & future hopes for one of the most challenging presentations of breast cancer. #ESMOBreast24
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Proffered paper session 1 at #ESMOBreast24: first results from #DOLAF trial showing very promising activity in advanced ER+/HER2- #BreastCancer of the combination #olaparib #durvalumab and #fulvestrant particularity in #BRCA carriers @myESMO #ESMOambassadors @OncoAlert #bcsm
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Benedetta Conte retweeted
Replying to @CarmenCriscit
@CarmenCriscit approaching several controversies in the real world oncology in BRCA/HR+ adjuvant scenario ▪️How to choose between CDKi and PARPi? ▪️ Are CDKi less effective in BRCAmut? ▪️ Can we combine at least sequentially CDKi and PARPi? #ESMOBreast24 #ESMOAmbassadors
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Benedetta Conte retweeted
Just out 🚨on @eBioMedicine Study explores the potential of a B-cell/immunoglobulin signature (IGG), alone or combined with tumor burden, to predict prognosis and treatment response in early-stage triple-negative #BreastCancer ➡️ indicating its promise in guiding personalized treatment decisions thelancet.com/journals/ebiom… @BenedettaConte5 @fara_bm @AdelaRodrguezH1 @TomasPascualMD @G_Villacampa @FrancescoSche20 @OlgaMartnezSez1 @MVidalMD @esther_sanfeliu @ClaudetteFalato @Nchic5 @AnaVivancosVHIO @patri0608 @prat_aleix
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🎯 B-cell/immunoglobulin signature (IGG) was associated with improved EFS (HR = 0.77) and OS (HR = 0.79) across 7 cohorts of early stage TNBC 🕵🏼‍♀️IGG + clinical features could help identifying pts benefitting from intensified or de-intensified tp 👏🏻 🤩@BenedettaConte5 @OncoAlert
Editor pick from April issue @BenedettaConte5 @prat_aleix @fara_bm & coll Identified a 14-gene immunoglobulin B-cell signature linked to improved prognosis and pathological complete response in patients with early-stage triple-negative breast cancer Read bit.ly/4b7WpYM
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Very happy to see that our paper on @eBioMedicine is the Editor's pick from the April issue! B-cell immunity is finally gaining its spot in the onocoimmunology field. In this paper we show how it is associated with pCR and prognosis in TNBC ⬇️@prat_aleix @evomet_itn @fara_bm
Editor pick from April issue @BenedettaConte5 @prat_aleix @fara_bm & coll Identified a 14-gene immunoglobulin B-cell signature linked to improved prognosis and pathological complete response in patients with early-stage triple-negative breast cancer Read bit.ly/4b7WpYM
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Benedetta Conte retweeted
👇Check this new article from our own @BenedettaConte5 @prat_aleix and @fara_bm 👏👏👏
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Out our new article on @eBioMedicine exploring the role of B-cell immunity in TNBC. 🧵below 🗞️open access here: authors.elsevier.com/sd/arti… @OncoAlert
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Finally, we used CIBERSORTx and ECOtyper to assess the immune cells and ecosystems reflected by IGG. IGG-high tumors are enriched for plasma cells, CD8+, and follicular helper cells, and belong to ecotypes CE9-10, corresponding to the highest levels of immunoreactivity
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Soon, we will present more data on the biological and clinical meaning of this signature in aggressive BC subtypes, by using more refined approaches such as single-cell RNAseq. Stay tuned!
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