Trying to understand how bariatric surgery work, we collaborate with physicians, use mouse models and apply mathematical tools ๐Ÿง#Obesity #NASH #NAFLD #Diabetes

Hadassah Medical School, Jerusalem, Israโ€ฆ
Joined February 2018
Ben-Zvi lab trip โ›ฐ๏ธ
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Happy Hanukkah ๐Ÿฅณ๐Ÿ•Ž
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Happy Hanukkah! โฆ@Hujimedโฉ โฆ@BenZvi_Labโฉ
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Sounds like a good idea ! Whoโ€™s in for a try ?
We make time for seminars that present new results, but we should also make time for โ€˜night scienceโ€™ discussions to generate new ideas together. Here are my tips for how to organize a thought-provoking night science session at your institution. ๐Ÿงต
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ืื ื™ืฉ ืœื›ื 1:45 ืœื”ืขื‘ื™ืจ ืœืžืฉืœ ื‘ื ืกื™ืขื”, ื•ื‘ื ืœื›ื ืœืฉืžื•ืข ืื•ืชื™ ืžืชืจืื™ื™ืŸ ืขืœ ื”ืจื–ื™ื”, ื”ืฉืžื ื” ื•ืจื™ืฆื•ืช ืฉื˜ื—, ืžื•ื–ืžื ื™ื ืœื”ืงืฉื™ื‘ ืœื’ื™ืงื•ื ื•ืžื™ geekonomy.net/2022/10/03/geeโ€ฆ ืืคืฉืจ ื’ื ืœืฉื™ื ื‘2x ๐Ÿค—
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(1/4) Did you know that there are bacteria in human tumors? Well, this is old news now ๐Ÿ˜Š. Our new study, featured on the cover of @CellCellPress, shows that human tumors contain fungi as well and that tumor fungi matter! (Cover by @munafomarzia) cell.com/cell/fulltext/S0092โ€ฆ
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Replying to @IdoWolf1 @12med865
ื”ื ื” ืชื™ืงื•ืŸ
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Which one is your stop ? ๐Ÿ˜… #GI #phdchat #phdlife
I love trainsโ€ฆand the GI tract.
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New study! We show that sleeve gastrectomy reduces glucose and cholesterol in lean female 5xFAD mice, but this has no effect on their #AD related behavior or pathology. A huge effort (and long shot) but I wanted to do this experiment since my postdoc. frontiersin.org/articles/10.โ€ฆ
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Excited to share our study by the legendary surgeon Dr Ronit Grinbaum, on the long term outcomes of #bariatric surgery in 4 adolescents with a LOF mutation in #mc4r. Weight remains high, but glucose improves (as in rodent models). mdpi.com/2218-1989/12/5/430 @Hadassah @Hujimed
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Cool!
We are excited to share our new work @Nature with @ThaissLab, uncovering the impact of ketogenic diet and beta-hydroxybutyrate on colorectal cancer, led by @OxDmitrieva. (1/7) nature.com/articles/s41586-0โ€ฆ
A bispecific #antibody which distinguishes #cancer cells from healthy cells, doesn't care about #KRAS mutations & was developed entirely on human cancer #organoids. In 3 years from drawing board to clinic. Congrats to all collaborators. Read: rdcu.be/cL4xS
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Finally out! We show that bariatric surgery in lean female mice leads to small for gestational age offspring, and development of glucose intolerance in male pups. This is reversed by glp1 receptor antagonism. A short thread below insight.jci.org/articles/vieโ€ฆ
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Ben-Zvi lab retweeted
We are looking for a #postdoc #PhD student for a collaborative project with a biotech company to develop RNA-based therapies for two genetic diseases. #Biotechnology #RNA #researcher
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Jerusalem snow day is like a holiday ! ๐Ÿ‚โ˜ƒ๏ธ
ืฉืœื’ ืขืœ ืขื™ืจื™ โ˜ƒ๏ธโ„ ๐Ÿ“ธ ืขื•ื‘ื“ื™ ืื’ืฃ ื—ื™ืจื•ื ื•ื‘ื™ื˜ื—ื•ืŸ ื‘ืื•ื ื™ื‘ืจืกื™ื˜ื” ื”ืขื‘ืจื™ืช
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Interesting cool work on MC3R ! Melanocortins are the best ๐Ÿง 
Nice to see this is now online nature.com/articles/s41586-0โ€ฆ Over the past ~30 years, the function of the central melanocortin system in receiving and responding to signals of nutritional state, including leptin and insulin, has progressively been unveiled/
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