@BenHuangLab

@UCSF acute myeloid leukemia: mouse cancer modeling, molecular therapeutics, functional genomics, and biomarker discovery. We're hiring postdoctoral scholars!

 UCSF Mission Bay
huanglabucsf.com/
Joined September 2022
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  • Followers56
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Excited to share that our work was published in @JCO_ASCO! A report from the @COGorg: stem cell transplantation is associated with improved outcomes for children diagnosed with high-risk acute myeloid leukemia (AML). ascopubs.org/doi/10.1200/JCO…

Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's...

PURPOSEHematopoietic stem cell transplantation (HSCT) is used as consolidation for pediatric patients with high-risk AML in first complete remission (CR1). The definition of high-risk AML has evolved...

ascopubs.org
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An incredible group effort that included leading investigators from: @UCSFCancer @UCSFPediatrics @SeattleChildren @UofR @USC @UofAlabama @StJudeResearch @LLSusa @ChildrensPhila @ChildrensLA @UMNPeds @ChildrensMercy @ChildrensATL @COGorg
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Excited to share our preprint (manuscript in review): TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia. @UCSFCancer biorxiv.org/content/10.1101/…

TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous cancer that is associated with poor outcomes. Revumenib and other menin inhibitors have shown promising activity against AMLs with KMT2A -rearrangeme...

biorxiv.org
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Excited to share that our work was published in @JCI_insight! We developed an inducible Ras isogenic cell line to provide insights into Raf activation. doi.org/10.1172/jci.insight.…. @UCSFCancer @theNCI.
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Last night, at the @StBaldricks event during the #COGFall2023Meeting, Todd Alonzo Braved the Shave for the 7th time! It's not too late to donate through Todd's page to help conquer kids' cancer: stbaldricks.org/participants…
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Excited to share about our contribution to a recent publication in @JClinicalInvest by the Meshinchi Lab. Targeting FOLR1 in CBFA2T3-GLIS2 AML. Using our computational pipeline to generate candidates, we are investigating promising immunotherapy targets. jci.org/articles/view/157101
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@UCSF @UCSFCancer @UCSFPediatrics @FredHutch
Excited to share that our work was published in @NatureComms! We combined a leukemia stem cell signature with established cytomolecular risk factors in AML to build a more robust and informed relapse prediction model. doi.org/10.1038/s41467-022-3…

Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid...

Nature Communications - Relapsed pediatric acute myeloid leukemia is associated with poor prognosis. Here, the authors use RNA-seq data from 1503 primary samples to create a combined...

nature.com
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Thank you to all of the collaborators and support that made this research possible! @UCSFCancer @FredHutch @StJudeResearch @NCIGenomics NCI TARGET @theNCI @COGorg @StBaldricks @RallyFoundation @ScottFurlan @TimTriche and so many others!
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The Huang Lab is hiring postdoctoral scholars (benhuanglab.ucsf.edu)! Email me at [email protected].

Huang Lab | UCSF

huanglabucsf.com
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