💙😇 "Reza las oraciones de la noche y vete a dormir" me decías. Ahora te rezo a tí: Ángel de la guarda dulce compañía guárdame de noche y acompáñame de día 💙

Contigo en el cielo algún día
Joined January 2012
💙😇 retweeted
Chemotherapy can create senescent cells that actually help tumors grow! A 2026 Nature Aging study showed that eliminating these cells with senolytics reduced tumor-promoting effects in lung cancer models. doi.org/10.1038/s43587-025-0… this is why we are excited about SenoMune-0257
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Can an old heart recover better after a heart attack? Researchers treated aged female mice with dasatinib + quercetin and found improved cardiac function and repair after myocardial infarction! doi.org/10.1016/j.mad.2022.1… this is why we are so exciting about SenoMune-0257
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Claude generated 318,484 protein designs in just 64 hours, working largely autonomously from one initial prompt and four follow ups. Researchers tested 211 candidates in the lab, and 17 successfully bound to four dangerous scorpion toxins, a promising first step toward new antivenoms for stings that kill more than 3,250 people annually, mostly children. Anthropic is releasing all 211 tested designs and their data.
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💙😇 retweeted
The damage from a heart attack continues long after blood flow returns! Mouse studies suggest senescent cells contribute to harmful ventricular remodeling—and that senolytics can improve functional recovery. doi.org/10.1038/s41514-023-0… this is why we are so exciting about SenoMune-0257
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💙😇 retweeted
We're excited to share results from our latest wet lab campaign with @AnthropicAI and @citrini. Claude designed novel proteins to neutralize scorpion toxins and we tested 211 of these protein designs in our automated wet lab. 17 of them showed binding to the toxins in our experiments, with all data now available on @proteinbase. This is a great example of what we're building towards: A world where anyone can run drug discovery campaigns on our automated wet lab.
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GLP-1 drugs may not be the first anti-aging drugs. Some drugs from the 1950s and 60s also slow aging. Nobody identified them well at the time. Drugs that extend life also tend to be anticancer. Some old drugs prescribed for other conditions turn out to have lowered cancer incidence in the patients who took them. I expect more of those drugs to come back as cancer drugs.
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Stocks and crypto pumping hard today after The Fed injects massive liquidity into the economy, which is only the start. More big injections will follow 🎯
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AI push into medicine is getting serious OpenAI just acquired Orchestra Bio, to combine its drug development agents with Rosalind AI, aiming to accelerate the entire journey from scientific discovery to new medicines reaching patients. The real AI revolution will be measured in lives saved.
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💙😇 retweeted
Iran deal reached ✅️ Oil falling like a rock ✅️ Yields collapsing ✅️ Best environment for yield sensitive, speculative stocks to rally. Keep it simple : 1. Yields down 2. Investors borrow more money 3. Gambles with risk assets $SOXX $IWM $BTC $ETH
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La prensa española confirma lo que publiqué sobre el despliegue militar marroquí. Mi información privilegiada me permitió adelantarme a unos medios que solo ahora empiezan a publicarlo, reforzando mi credibilidad.
🚨 Ojo: #Marruecos ya no podrá trasladar ningún tipo de material militar pesado, como blindados, artillería o misiles, ni desplegarlo dentro de su territorio en los 300 kilómetros siguientes a las fronteras de las ciudades de #Ceuta y #Melilla. Del mismo modo, #Rabat no podrá realizar vuelos de aeronaves de combate dentro de su territorio en esa misma franja de 300 kilómetros desde las fronteras de las ciudades de #Ceuta y #Melilla sin informar previamente al mando militar español. Además, cualquier ejercicio en el que participen aviones F-16 marroquíes deberá contar con la aprobación previa de #España, una vez que se le hayan facilitado detalles precisos sobre los lugares en los que se llevarán a cabo dichos ejercicios.
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💙😇 retweeted
Six days ago I replied to @bryan_johnson about my cancer vaccine. That reply put my story in front of a lot shit ton of new people. Since then: ~1M impressions, 5.5K profile visits, ~550 replies, and 60+ DM's and emails. The part I didn't expect: a lot of it wasn't well-wishes. It was real help. Jan Domański, a scientist at OpenFold, offered to model my cancer's resistance mutations with AI, for free. Dennis Watson at Travera offered immune testing to track how my vaccine is working. @miriamgonp, a fellow patient, is building her own vaccine path, and we're comparing notes. Thank you, Bryan, and thank you to everyone who reached out. I read every message. If you're someone who wants to help or better yet if I can help you in any way, my DMs are open.
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youtu.be/sIsaEpAhkeQ?si=hmlu… PDSB : IL12 $ibrx immunotherapy is unstoppable
MASSIVE MASSIVE BUY!!!!! Papillary Approved - NO COMPETITORS! non-invasive! high complete response! ...... and 25% lower than annual highs!!!!???? $IBRX
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The biggest IPO warning in 100 years. This pattern has NEVER failed. 1928 → Goldman Sachs 1971 → Intel 2000 → AT&T Wireless 2026 → Anthropic Each mega IPO arrived exactly on the peak of a major market bubble. Then the S&P 500 crashed: → 1929 crash: 86% → 1973 crash: 53% → 2000 crash: 51% → 2026 crash: **% And Anthropic is the final liquidity event before the AI bubble breaks. Remember, I’ve been trading markets for over 15 years. When I EXIT the markets completely, I’ll say it here publicly, like I always do. Turn notifications on. If you’re not following yet, you’ll understand why that was a mistake later.
🚨 SOMETHING VERY STRANGE IS HAPPENING The stock market keeps pushing to new all-time highs. But nobody is paying attention to what’s actually happening. OpenAI and Anthropic are now worth $3.4T+. That’s 10% of the entire Nasdaq-100. Numbers don’t lie: - $1.37T+ in spendings - $75B in actual revenue The biggest AI players are losing hundreds of billions per year. Not listed. Not profitable. And still being priced higher. The playbook: - Big players funding each other - Partnerships that look good on paper - Revenue that never leaves the system This has happened before. 2000: - Companies with no profits. - Massive valuations. - Narratives driving everything Then reality hit. Nasdaq collapsed -80%. You’re watching it happen in real time: the final sign of mania. Companies rebrand as “AI”… and reprice instantly. This is no longer investing. It’s a bubble detached from reality. They break. For the record, I’ve predicted all the market tops and bottoms for the last 15 years, including the exact Bitcoin bottom at $16,000 three years ago and the top at $126,000 in October. If you missed those calls, don’t worry. I’ll call the next one too. Turn notifications on. If you’re not following yet, you’ll understand why that was a mistake later.
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Next Science
@NextScienceOct 20
🧬 At Just 15, He Earned a Doctorate in Quantum Physics. Now He Wants to Tackle Aging. What if the next breakthrough in human longevity came from a teenager? Meet Laurent Simons, a Belgian prodigy who reportedly earned his PhD in quantum physics at the University of Antwerp in November 2025. His research explored the strange behavior of particles in superfluids and supersolids, two unusual states of matter. But his scientific journey doesn't stop there. His next goal is to explore artificial intelligence and longevity through further doctoral research in Munich, Germany. His dream? To help people stay healthier for longer. Can science eventually slow the biological processes that make us age? No one has found a way to stop human aging, but researchers are exploring new ways to understand and prevent age-related diseases. At just 15, Laurent is entering a field filled with enormous questions. Could his generation bring us closer to understanding the secrets of aging? Source The Brussels Times. (2025). Reporting on Belgian teenage prodigy Laurent Simons and his doctoral research.
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2) You don’t need to fix all the damage Aubrey’s point is that escape velocity means repairing the damage of aging faster than the body creates it. If we can do that, our biological age stops rising. @aubreydegrey
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🚨 إيلون ماسك يحطم مخاوف العالم بضربة واحدة: "عصر الدخل الأساسي انتهى.. وأهلاً بكم في عصر الثروة الفائقة والدخل المرتفع الشامل للجميع!" ​في رؤية زلزالية يطرحها أغنى رجل في العالم لإنهاء كابوس "سرقة الوظائف": ​ ​وداعاً للفقر: لن نعتمد على "الدخل الأساسي (UBI)" كمعونة اجتماعية، بل سنتجه مباشرة لـ "الدخل المرتفع الشامل (Universal High Income)" حيث يصبح كل إنسان على الأرض مليونيراً بالوفرة والخدمات! ​رواية الخيال العلمي كواقع: ماسك يعتمد على نموذج "The Culture" لإيان بانكس كخارطة طريق لعصر ما بعد الندرة، حيث تدير الائتمانات الذكية الإنتاج، بينما يستكشف البشر الكون ويعيشون في رفاهية مطلقة. ​نهاية العمل للبقاء: أيام الوظائف المملة لدفع الفواتير ستصبح من الماضي.. وسيتفرغ البشر بالكامل للاستكشاف، الفن، والشغف الكوني. ​الذكاء الاصطناعي لن يدمرنا.. بل سيحررنا لنغزو النجوم! ​احفظ التغريدة وشاركها مع أصدقائك! 🧵👇
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イーロン・マスク「老化や病気なんてテクノロジーでいくらでも修正できる、寿命はもっと伸ばせるし、若さも保てる。」 「体全体が一斉に老いるなら、背後に『プログラム』があるはずだ。プログラムなら書き換えられる」――エンジニア視点で解き明かす「老化のリバースエンジニアリング」 「『人は誰でも老いて死ぬのが自然の摂理』というフワッとした諦めを、エンジニアの論理が一撃で論破」 イーロン・マスクが「工学(エンジニアリング)の視点」で突きつける、老化のロジックをわかりやすく👇 ・「全身が一斉に衰える」のは、中心にプログラムがある証拠 もし老化が単なるランダムな摩耗やカオスなら、臓器ごとにガタがくる時期がバラバラなはず。だが実際は、体全体が見事なまでに同期して衰退していく。つまり、その背後には全身の老化をコントロールしている「生物学的時計(プログラム)」が確実に存在する。 ・「運命」ではなく「コード」なら、人間が書き換えられる 神の摂理でも何でもない。単なる生物学的なプログラム(コード)で老いるように設定されているだけなら、エンジニアリングの手法で書き換えればいいだけの話。「設計されたもの」であるなら、人間が「逆解析(リバースエンジニアリング)」して元に戻すことだって絶対に可能。 ・地球上の他の生物はとっくに「寿命の壁」を突破している クジラは200年以上生き、ニシオンデンザメに至っては最大500年も海を泳ぎ続ける。長寿や細胞の維持は、オカルトや奇跡ではなく、すでに地球上の生物界で証明済みの「ただの生物学と工学の仕組み」に過ぎない。 ・がん、認知症、血管の劣化は「不可避」ではなく「選択制」へ 年を取ったら病気になるのが当たり前、という時代は終わる。イーロンのような狂気の資金力、影響力、そして異常な開発スピードを持つエンジニア集団が本格的に参入すれば、加齢に伴う恐ろしい病気は「避けられない運命」から「治療して回避できるオプション」へと激変する。 要するに、「『人はいつか老いて死ぬものだ』というオカルトじみた諦めを捨て、全身をきれいに劣化させている『老化プログラム』のコードを逆解析(リバースエンジニアリング)して書き換えてしまえば、老化や病気なんてテクノロジーでいくらでも修正できる単なるシステムエラー(バグ)に過ぎなくなる」ということです。
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sidequestmaxxing next year is going to be quite unhinged - veradermics hair regrowth pills making hairlines respawn - your aunt getting on reta "for the vibes" and dropping 20 lbs - cousin flying to turkey for a stem cell shot in his knee, back in the gym 2 weeks later - the groupchat running blood panels to see who has the youngest biological age - folks bringing peptides to dinner like tic tacs - your miami high school friend getting a one-time gene therapy - dad asking for the mouse lifespan extension shot - your buddy freezing sperm because the timeline is accelerating the next civilization won't even be planned, it's accidentally arriving fast. bio/acc.
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Bullish on biotech
A weekly jab in the belly is generating more revenue than the entire AI industry. Ozempic + Mounjaro: $71B in 2025. OpenAI + Anthropic: $29B. And they've barely started. ~2% of the 800 million eligible patients can currently access them. h/t @DrSamuelBHume
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