
Cancer surgeon-scientist @PennMedicine. Our lab advances therapy for #headandneckcancer #HPV #hnscm. Opinions my own. Patient appointments 2156626972
Philadelphia
Joined May 2019
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It was a privilege to present today at the 9th annual DDR Summit in Boston , representing the @PennCancer
team advancing translational science and clinical trials for HPV+ head and neck cancer @DiabLabPenn @DrNickLukens @LovaSunMD
Best oral abstract in HPV+ OPC session at #AHNS2025! Congrats to presenter JN Gallant, MD, PhD and rest of @basulab1 team for our study that links an expanded subset of tumor cells with low HPV E6/E7 expression to recurrence risk after TORS-based therapy @Penn_ENT @PennCancer
Replying to @JNCI_Now
@JNCI_Now We defined the gene expression profiles distinguishing HPV+ OPSCCs that are prone to recur after TORS-based therapy. These the tumor-intrinsic and immune-related traits were tightly interrelated and generalizeable to nonsurgical cases as well. academic.oup.com/jnci/advanc…
Sharing our brief review on how the differences in HPV oncogene expression spanning 3 orders of magnitude among oropharyngeal cancers impact their behavior and clinical outcomes - it’s brief because little is known… sciencedirect.com/science/ar…….
It was a privilege to host @lab_pearson together with @LovaSunMD as part of our Head and Neck Cancer Center of Excellence lecture series and learn about progress toward AI-based discrimination of actionable states for cancer therapy.
Congrats to Dominick Rich MS2 @Penn_ENT @PennCancer winning best Cancer Biology oral abstract, reporting our work on defining HPV+ OPSCC recurrence risk at AHNS @__COSM
I'm pleased to share our new pipeline for identifying new drug targets for specific cancer types. The algorithm integrates DepMap CRISPR screens with multiple other public databases. The pipeline and its output for HPV(-) HNSCC are detailed here. febs.onlinelibrary.wiley.com…
Was quoted by ASCO Post recently on the low public awareness of HPV as a cause of oropharynx cancer ascopost.com/issues/june-10-…
Thanks to @Triological for the invite and support in helping Niels and me put together this panel!
Appreciate the shout out on the Penn Medicine News
Blog today citing our work with @ewhite_lab and @DanKellyPennCVI to understand disparate treatment responses among HPV+ oropharyngeal cancers pennmedicine.org/news/news-b…















