Correct answer: B) Nitrates Nitrates are most commonly associated with postural (orthostatic) hypotension because they cause significant venodilation, reducing venous return (preload). This effect can be particularly pronounced when the patient suddenly stands. ⬜ Nitrates: prominent postural hypotension 🟨 Alpha-blockers: also classically associated with postural hypotension, especially the first-dose effect ⬛ Beta-blockers: may contribute, but less commonly 🟪 ACE inhibitors: generally have a lower risk 🟩 Calcium channel blockers: can cause hypotension, but postural hypotension is less characteristic