This award-winning microscopy image used AI — igniting controversy in a prestigious competition nature.com/articles/d41586-0…

Can small extracellular vesicles guide growing axons? Our new preprint provides evidence that small extracellular vesicle (sEV) secretion regulates axon guidance at a key ventral midline choice point during spinal cord development. biorxiv.org/content/10.64898… #neuroscience #EV

The tissue shown here is an ex vivo culture of intact spinal cord from a🐣embryo, allowing us to observe these processes in a controlled yet physiologically relevant setting.What looks like a simple crossing event emerges from complex and tightly regulated cellular processes.

During development, these neurons extend long projections that grow toward the midline, cross it, and then turn to grow along the length of the spinal cord. This coordinated behavior is essential for establishing connectivity between the two sides of the nervous system.

These are dI1 neurons, a well-studied class of spinal interneurons that have been used for more than 30 years to uncover fundamental mechanisms of axon guidance and neural circuit formation.

Wiring Both Sides of the Nervous System 🔬 #FluorescenceFriday #Neuroscience #DevelopmentalBiology #Microscopy #LifeSciences This video shows axons crossing the midline of the developing spinal cord.

A Sticky Dance Between a Cell and a Neuron. #neuroscience #science #mysterious #HiddenWorld #cell #FluorescenceFriday ➡️A Schwann cell precursor interacting with sensory axons 🔬🧫

This is how actin shapes the neuronal growth cone 🔬 When a neuron grows, it doesn’t just extend blindly. It actively moves, explores its surroundings, and makes decisions along the way. #Neuroscience #ScienceCommunication #Microscopy #brain #Science #LifeSciences #neuron

more videos on my new youtube channel: youtube.com/@AlexNeuroHealth

This Is What Drives Axon Growth. Axon growth is powered by the actin cytoskeleton at the growth cone. Here, filamentous actin dynamics drive fast, directed axon extension in real time. #Fluorescencefriday #science #neuroscience

Here’s an embryonic axonal growth cone labeled with PK Mem dye (red) and tubulin (blue), imaged every 2 seconds. 🤩

Thrilled to collaborate with @ZhixingChen2 Lab @PKU1898! We tested new PK Mem dyes—gentle, photostable tools to label the plasma membrane in live neurons, making it easier to track growth cone motility & axonal transport. #liveimaging #neuroscience tiny.cc/3qhp001

This time-lapse captures 17h of axonal growth from a chick dorsal root ganglion explant, seen through the actin cytoskeleton using live imaging. I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours!😉 #neuroscience