Investigating the role of NK cells in cancer and viral infection. Account run by lab members. @McMasterU @MacImmunology

Joined November 2019
Join us next Thursday for visiting speaker Dr. Ali Ashkar from @McMasterU. Interferon Types and Time Matter is the discussion topic. @Ashkar_Lab @UM_RadyFHS @um_research
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While CD56 expression could be used to indicate a hyper-functional state of NK cells, it does not directly influence the anti-tumor functions of expanded NK cells @jlb_journal Congrats, @Ana_LPortillo! @Ashkar_Lab doi.org/10.1093/jleuko/qiae2…
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Why does covalency matter? Here we develop a new covalent #inducedproximity system that activates T cell tumoricidal function through stabilized ternary complexes. Covalency is observed to uniquely enforce immune receptor activation signaling events! doi.org/10.1016/j.omton.2024…
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Ashkar Lab retweeted
Joseph Sun Lab@SunLab_Official17 May 2024
Check out the latest issue of Immunological Reviews on innate immunity (with an adaptive twist!) where @JosefowiczLab and I convinced a bunch of talented colleagues to contribute. onlinelibrary.wiley.com/toc/…
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Excited to share my very first publication! Thanks Maz for giving me the chance to write about innate immune memory- a new concept to us, but an ancient phenomenon.
"Discovering adaptive features of innate immune memory" In this review with super talented @minasadeghii we discuss how evolutionary, mitochondria and cellular metabolism along with diverse signaling pathways shape innate memory responses. doi.org/10.1111/imr.13328
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Long Presentation Winners: 1st place: @LiamERondeau 2nd place: Ana Portillo 3rd place: Ann Kuganathan
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Congrats to all @CdnImmunol conference travel award winners! Special shout out to @UM_Immu students @OlamideOgungbo1 (our lab), @submarinahere & Diane Tshikudi & #IFNL enthusiast/collaborator @Emily_YF_Feng 🎉🥳👏🏻 Looking forward to seeing everyone in Banff at #CSI2024 😀
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Ashkar Lab retweeted
Excited to share my research was published today @NatureComms ! We find that bystander activated T cells, rather than the virus itself, is responsible for virus-associated neurological disease! @Ashkar_Lab @MacImmunology @machealthsci @McMasterIIDR nature.com/articles/s41467-0…
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Save the date! #CanNKC2024 will be held June 13-14, 2024 @uOttawa! Stay tuned for more details!
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Congratulations to Sophie Poznanski, PhD from @Ashkar_Lab, who received one of two Governor General's Academic Gold Medals, awarded to a graduating student achieving the highest academic standing at the grad level! dailynews.mcmaster.ca/articl…
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Immunotherapy pioneer Dr. Steven Rosenberg of NCI has been awarded the highest honor for technological achievement by @POTUS, the National Medal of Technology and Innovation, for his contributions to America’s economic, environmental, and social well-being spr.ly/6013uer7l
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Up next, science! #CSI2023 @CdnImmunol
Enjoying the scenery in Orford before #CSI2023 with @LizBalint and @Emily_YF_Feng
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Enjoying the scenery in Orford before #CSI2023 with @LizBalint and @Emily_YF_Feng
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Late to the party (I'm a bad wing-supervisor) BUT mega congrats to best trainee speaker, @NersesianSarah !!
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I'm so honoured to be a part of this team and community. Read about some of our work here. @morganpughtoole @NersesianSarah @AnnaNicolela
We interviewed Dr. @JeanetteEB, scientific director at the @BHCRI and associate professor at @DalhousieU in Halifax, to learn more about her work in harnessing the power of natural killer (NK) cells for #immunotherapy in #ovariancancers. bit.ly/BoudreauNKCells
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Ashkar Lab retweeted
Our final keynote speaker is @JeanetteEB, a world-class immunologist investigating the anti-tumour functions of #NK cells!#CanNKC2023
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Ashkar Lab retweeted
We are excited to announce our second keynote speaker, @SunLab_Official for our inaugural #CanNKC2023 symposium! Dr. Joseph Sun is a forefront research investigating the development and activation of memory NK cells during viral infections!
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Excited to share this brief report by me and my undergrad Jonathan Monteiro! We look into how #NKcells can regulate pathogenic macrophage activity @Ashkar_Lab @MacImmunology #Interferons
NK cell-derived IFN-γ regulates macrophage-mediated immunopathology during viral infection ✅ Just Accepted 🔗 bit.ly/43jpxZT
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