PostDoc @TheCrick BioDesign Lab, previously @WeTheBarEvenLab & @erblabs – exploring synthetic biology and metabolism of one-carbon compounds
Joined May 2017
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Excited to share a main project from my PhD, out now in @NatureComms! 📝
We've designed and brought to life the “CORE cycle” – a new-to-nature pathway that provides a novel route for biological CO2 capture 🦠🌱
nature.com/articles/s41467-0…
Take a look! Thread below... 🧵
Ari Satanowski retweeted
🌿🔬How can we fix #CO2 more efficiently in biological systems? Our new study introduces the CORE cycle, a synthetic pathway that converts CO2 to formate at aerobic conditions and ambient CO2 levels! 🚀🦠 @erblabs @mpi_marburg nature.com/articles/s41467-0…
I’m deeply grateful to my PhD advisors @erblabs and @wethebarevenlab, who enabled this work and helped shaping the team around it.
📖 Read the full story here, and let us know what you think:
nature.com/articles/s41467-0…
For future updates, see you over at Bluesky
bsky.app/profile/ari-satanow…
(by the way, brilliant tool to quickly migrate the people you followed from Twitter: “Sky Follower Bridge”)
Ari Satanowski retweeted
New research from GAIN4CROPS compares alternative pathways to photorespiration—a metabolic process that reduces plant efficiency & crop yields.
A key finding: Carbon-fixing pathways like TaCo are the most promising ones.
#PlantScience #Photorespiration
science.org/doi/10.1126/scia…
Ari Satanowski retweeted
Top 4 things to know about doing science:
1. You need to have someone you can talk to
2. One-on-one discussions are the best
3. Think about discussions as improvisations and use the ‘yes, and’ rule
4. Create a safe space so both of you feel open to saying seemingly silly things
Ari Satanowski retweeted
Looking for some holiday reading? Wondering how #cellfree systems are creating new opportunities in manufacturing, diagnostics, and education? Check out our open access comprehensive review, with @akarimlab @Andrew_C_Hunt Blake Rasor @ktwarfel @NUSynBio
pubs.acs.org/doi/10.1021/acs…
Ari Satanowski retweeted
📢We invite candidates strongly interested in 𝗶𝗻𝘁𝗲𝗿𝗱𝗶𝘀𝗰𝗶𝗽𝗹𝗶𝗻𝗮𝗿𝘆 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻 𝗺𝗼𝗱𝗲𝗿𝗻 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗹𝗼𝗴𝘆 to apply for 𝗳𝘂𝗹𝗹𝘆-𝗳𝘂𝗻𝗱𝗲𝗱 𝗣𝗵𝗗 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻𝘀.
Curious to learn more? See this 🧵 or visit
imprs-marburg.mpg.de
Ari Satanowski retweeted
How to get a slow enzyme 🐌 to perform new tricks🏃 ? @mirbachh, @p__wichmann @erblabs, @AriSatanowski and colleagues have developed a new-to-nature #enzyme for efficient conversion of #CO2 into valuable products via AcetylCoA. 🌿🧪 #SynBio
mpi-marburg.mpg.de/1481487/2…
Paper alert! 🎉
Excited to share this collaboration from my PhD time @wethebarevenlab and @erblabs!
We built a new bridge in central metabolism, connecting acetyl-CoA and pyruvate via a novel, engineered pathway.
For some personal highlights, come along 🧵
nature.com/articles/s41467-0…
12/ I’m extremely grateful to my co-first authors @mirbachh and @p__wichmann for bringing this pathway to life together. Make sure to head over to the thread by @mirbachh for more angles to our story, with a fabulous drawing of our LCM-E.coli:
xitter.cf/mirbachh/status/186138…
Lets talk about #acetyl-CoA! As central molecule in C1 metabolism, the efficiency of its assimilation determines yields. Read below about our Lcm as novel activity in the shortest O2 tolerant route to make pyruvate from acetyl-CoA while fixing #CO2!
nature.com/articles/s41467-0…
13/ Curious about our methodology, future applications and evolved enzyme mutants? Check out the paper below.
We'd love to hear your thoughts!
nature.com/articles/s41467-0…