Doctoral Student @NYUniversity | BS-MS (Bio.) @iiserbhopal ('18-'23) | iGEM '20, '21
Mumbai, India
Joined December 2016
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Archit Devarajan retweeted
New paper from our lab @IISERPune led by @karthikgs24 & @amolm04, helped by @the_dope_drug, @ArchitDevarajan & Anisha, on developing a bifunctional lipid probe & chemical proteomics on mapping protein ligands for MAG lipids. @Hari_Chakrapani @CommsChem
nature.com/articles/s42004-0…
Do check it out!!
A new paper on @ArnabChaks & @ArchitDevarajan’s collaborative work from our lab @IISERPune, with help from @Kundan703 & Rohith is now online @BiochemistryACS.
pubs.acs.org/doi/10.1021/acs…
Archit Devarajan retweeted
Do check out a new preprint from the lab @IISERPune on the bioinformatics analysis and biochemical characterization of ABHD12. Nice work spearheaded by @ArnabChaks & @ArchitDevarajan, with help from @Kundan703 & Rohith.
biorxiv.org/content/10.1101/…
Archit Devarajan retweeted
A new preprint from the lab @IISERPune describing use of chemoproteomics platforms in identifying hitherto unknown MAG protein ligands via MAG probes. Nice work by @karthikgs24, @amolm04, @the_dope_drug, @ArchitDevarajan in collab. with @Hari_Chakrapani. biorxiv.org/content/10.1101/…
The work that I contributed to as a Mitacs Research Intern is now out in @CellReports!! We report the development of a CRISPRi-seq-based technique for chemical-genetic profiling of antimicrobials and identify a novel inhibitor of the essential enzyme peptidyl-tRNA hydrolase.
Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase dlvr.it/TGB9Hx
Super grateful to @cardona_lab and @zisanurrahman for allowing me to contribute to this work!
Heartiest Congratulations @KamatLab_IISER!!! Extremely proud to be a lab alumnus!!
#InfosysPrize2024 in Life Sciences is awarded to Prof. Siddhesh Kamat, @KamatLab_IISER, of @IISERPune for his discoveries concerning bioactive lipids and their receptors, and their metabolic and signaling pathways. His research using advanced methods to understand the function of lipids, a key component of cells, has important implications for understanding the role of these molecules in a range of cellular functions and human diseases.
Archit Devarajan retweeted
It’s just a tiny bottle.. It probably doesn’t smell that bad
Tiny Bottle:
ALT 2-mercaptoethanol bottle
Archit Devarajan retweeted
Today was @ArchitDevarajan & @ChaitanyaKatka4’s last day in lab @IISERPune. Both have been wonderful & very productive researchers over the past year & now move on to their PhD’s. Looking forward to exciting science from them. (Pic from their farewell lunch today).
Thank you @cardona_lab, @zisanurrahman and all Cardona Lab Members for a memorable training opportunity full of learning!
📣new from our lab: essential antibacterial targets served in a single test tube! Thanks to the work of
@zisanurrahman @J_Novomisky @ArchitDevarajan in collaboration with @UIC_BioS Yuri Polikanov and Egor Syroegin
#CRISPRi #antibiotics #burkholderia #AMR
My review article has been featured on front cover of the January 2024 issue of @ACSSynBio!
Link to the article:
pubs.acs.org/doi/10.1021/acs…
@ACS4Authors #MyACSCover
Excited to share my review article on optical-control of #CRISPR-Cas9 and Cre recombinase for gene editing! I talk about the strategies in detail, summarize key challenges & discuss the therapeutic promise of optical-control.
pubs.acs.org/doi/10.1021/acs…
@iiserbhopal @ACSSynBio
Archit Devarajan retweeted
#Breaking: The U.S. FDA approves the CRISPR/Cas9 gene-edited treatment, co-developed with Vertex Pharmaceuticals, for #SickleCellDisease. Learn more: bit.ly/4apMw9p
Archit Devarajan retweeted
Another major milestone towards not being beholden to the misspellings in our DNA. Congratulations to @CRISPRTX, @VertexPharma, the many scientists and doctors who laid the intellectual foundations for this work, and the patients who will benefit from it. 🍻
Archit Devarajan retweeted
In vivo base editing works in humans!
Congratulations to @KomorLab, @NicoleGaudelli, and @davidrliu for advancing gene editing science and inventing base editing technology!
Great work by both the @BeamTx team and the Verve team to make it happen! @skathire and @ambellinger 👏🎉
Archit Devarajan retweeted
In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK.
“A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory Agency (MHRA) for patients aged 12 and over after a rigorous assessment of its safety, quality and effectiveness.”
Congratulations to the many scientists, doctors, patients, and industry leaders who made this development possible.🍻
gov.uk/government/news/mhra-…
Archit Devarajan retweeted
New paper on the bioinformatics analysis and biochemical characterization of ABHD14 proteins is now online: onlinelibrary.wiley.com/doi/… Very nice work by @_nottheriver @itsmesonaaaa @ArchitDevarajan and @MihikaYeolekar from lab.
Archit Devarajan retweeted
Over the last 10 years, the #CRISPR toolbox and its applications have profoundly changed biological research, enabling advances through applications in plants, animals, and humans.
A #ScienceReview highlights a decade of the technology: scim.ag/4wq #WorldCRISPRDay
Archit Devarajan retweeted
It’s the first time a frog—or any amphibian—has been observed pollinating a plant. scim.ag/42S @NewsfromScience
Thank you so much for the opportunity @KamatLab_IISER!
Happy to share a collaborative preprint from our and Madhu's lab @IISERPune. Very nice work by @_nottheriver and @itsmesonaaaa with help from @ArchitDevarajan and @MihikaYeolekar from our lab. biorxiv.org/content/10.1101/…
