@AppliedCVB

International Society For Applied Cardiovascular Biology

ISACB.org
Joined November 2012
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  • Followers510
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Registration is now open for the ISACB 2026 Biennial Meeting in Miami! Register by September 12 to join us from November 11-14th, 2026! isacb.wildapricot.org/event-…
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Member publication alert: Model Matters: Genetic Architecture and Cardiovascular Physiology in Translational Medicine jacc.org/doi/10.1016/j.jacbt…

Model Matters: Genetic Architecture and Cardiovascular Physiology in Translational Medicine

jacc.org
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Member publication alert: Vitamin B6 Modification of Bovine Pericardial Bioprosthetic Heart Valve Leaflets Promotes Blood Outgrowth Endothelial Cell Adhesion onlinelibrary.wiley.com/doi/…

Vitamin B6 Modification of Bovine Pericardial Bioprosthetic Heart Valve Leaflets Promotes Blood...

Bioprosthetic heart valves (BHV), typically fabricated from glutaraldehyde-fixed bovine pericardium (BP), are the most common type of replacement for patients with severe heart valve disease....

onlinelibrary.wiley.com
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Member publication alert: Emerging Technologies in Cardiovascular Disease Modeling: Bridging Basic Science and Clinical Translation mdpi.com/2073-4409/15/19/175…

Emerging Technologies in Cardiovascular Disease Modeling: Bridging Basic Science and Clinical...

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, yet therapeutic development is limited by experimental models that incompletely recapitulate human physiology, disease...

mdpi.com
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Member publication alert: Fibro-Adipogenic Progenitors From Skeletal Muscle Enhance Microvascular Angiogenesis in a 3D Model advanced.onlinelibrary.wiley…

Fibro‐Adipogenic Progenitors From Skeletal Muscle Enhance Microvascular Angiogenesis in a 3D Model

Fibro-adipogenic progenitors (FAPs) are skeletal muscle stem cells that reside between fibers and near capillaries. However, relatively few studies have investigated interactions between FAPs and...

advanced.onlinelibrary.wiley.com
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Member publication alert: Editorial: Investigating the role of extracellular vesicles in cardiovascular disease mechanisms frontiersin.org/journals/car…

Frontiers | Editorial: Investigating the role of extracellular vesicles in cardiovascular disease...

As key mediators of local and distant intercellular communication, extracellular vesicles (EVs) have emerged as an increasingly important focus in cardiovasc...

frontiersin.org
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Member publication alert: Thrombogenicity of stent graft materials as a potential contributing factor to limb graft occlusions jvsvs.org/article/S2666-3503…

Thrombogenicity of stent graft materials as a potential contributing factor to limb graft occlusions

Limb graft occlusions (LGOs) remain a significant complication after endovascular aneurysm repair. Several clinical risk factors have been recognized, but these do not fully account for the consist...

jvsvs.org
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Member publication alert: Effect of Shear-Induced Macrophage Secretome on Endothelial Permeability annalsthoracicsurgery.org/ar…

Effect of Shear-Induced Macrophage Secretome on Endothelial Permeability

Discrete subaortic stenosis (DSS) is a pediatric cardiovascular disease marked by fibrotic growth within the left ventricular outflow tract (LVOT), leading to severe complications, including left...

annalsthoracicsurgery.org
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Member publication alert: Patient-Specific Analysis of Ventricular Vortex Formation and Flow Energetics in Rheumatic and Calcific Mitral Stenosis link.springer.com/article/10…

Patient-Specific Analysis of Ventricular Vortex Formation and Flow Energetics in Rheumatic and...

Annals of Biomedical Engineering - Mitral stenosis (MS) accounts for 12% of cardiac patients with single valve disease. There are two main causes: rheumatic disease of the mitral valve (MV) and...

link.springer.com
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Member publication alert: Human trilayer engineered blood vessel reveals influence of fibroblasts on disease progression in model of Hutchinson-Gilford progeria science.org/doi/10.1126/scia…

Human trilayer engineered blood vessel reveals influence of fibroblasts on disease progression in...

In vitro models of vascular disease have focused primarily on the pathophysiology of smooth muscle cell (SMC) or endothelial cell (EC). Adventitial fibroblasts can contribute to disease progression,...

science.org
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Columbia scientists discover surprising link between serotonin and heart valve disease sciencedaily.com/releases/20… @lab_ferrari

Columbia scientists discover surprising link between serotonin and heart valve disease

Scientists have uncovered evidence that serotonin, the chemical best known for regulating mood, may also speed the progression of a common heart valve disease in some people. The research suggests...

sciencedaily.com
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ONE MONTH UNTIL ISACB 2026! - mailchi.mp/1bd52251f1b8/isac…
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Listen to @AppliedCVB member @craig_goergen's conversation about biomedical imaging with @LizWaynePhD on the @BMESociety Office Hours podcast! bmes.org/podcast/officehours…

Office Hours: Episode 15

Explore how Dr. Craig Goergen leverages advanced biomedical imaging to bridge research and clinical applications, enhancing understanding of diseases and promoting interdisciplinary collaboration.

bmes.org
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Member publication alert: Loss of Chromosome Y and Risk of Abdominal Aortic Aneurysm jamanetwork.com/journals/jam…

Loss of Chromosome Y and Risk of Abdominal Aortic Aneurysm

This cohort study evaluates the association between loss of chromosome Y and the incidence of aortic aneurysm based on anatomic location.

jamanetwork.com
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Member publication alert: From mummies to internal mammaries: A historical perspective on the development of cardiovascular bypass surgery journals.bioscientifica.com/…

From mummies to internal mammaries: A historical perspective on the development of cardiovascular...

AbstractObjectives. To explore the historical development of contemporary surgical revascularization techniques.Methods. This narrative review synthesizes historical medical literature, surgical case...

journals.bioscientifica.com
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Member publication alert: Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune-Shielded Heart Valves advanced.onlinelibrary.wiley…

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐S...

Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune-evasion genes US2 and Serpin b9 into donor valve cells...

advanced.onlinelibrary.wiley.com
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Member publication alert: Remnant virus proteins sustain vascular inflammation post coronavirus infection in mice and humans portlandpress.com/clinsci/ar…

Remnant virus proteins sustain vascular inflammation post coronavirus infection in mice and humans

Abstract. SARS-CoV-2 coronavirus infections are associated with long-term vascular dysfunction, yet the drivers remain unclear. We hypothesized that remnant Betacoronavirus antigens remain in...

portlandpress.com
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Member publication alert: Bioprosthetic heart valve degeneration: new insights into structural remodeling and calcification frontiersin.org/journals/car…

Frontiers | Bioprosthetic heart valve degeneration: new insights into structural remodeling and...

Bioprosthetic heart valves (BHVs) are widely used to treat aortic valve disease, and their demand is rising. However, BHV lifespan remains limited by degener...

frontiersin.org
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Member publication alert: The PEDIAVALVE project - tissue-engineered pulmonary valves for paediatric valvular replacement frontiersin.org/journals/bio…

Frontiers | The PEDIAVALVE project – tissue-engineered pulmonary valves for paediatric valvular...

Current paediatric options for pulmonary heart valve (PHV) substitutes are imperfect, requiring numerous reinterventions until maturity. Substitutes with a d...

frontiersin.org
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Member publication alert: Non-invading cells that coordinate with tip cells during angiogenic sprout initiation exhibit a molecular signature driven by YAP and TAZ journals.physiology.org/doi/…

Non-invading cells that coordinate with tip cells during angiogenic sprout initiation exhibit a...

Angiogenesis requires endothelial cell (EC) plasticity and differentiation into either invasive, migratory tip cells or proliferative stalk cells. Using a transcriptional analysis that distinguished...

journals.physiology.org
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Member publication alert: Healthy bone marrow transplantation into hypertriglyceridemic rats improves cardiac reparative fibrosis post-myocardial infarction academic.oup.com/cardiovascr…

Healthy bone marrow transplantation into hypertriglyceridemic rats improves cardiac reparative...

AbstractAims. Acute myocardial infarction (AMI) triggers an immune response characterized by a dynamic interplay between the bone marrow (BM) and the ischa

academic.oup.com
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