@AppSysBio

Research Group Applied Systems Biology headed by Prof. Dr. Marc Thilo Figge at the Leibniz Institute for Natural Product Research and Infection Biology in Jena

 Jena, Germany
asb.hki-jena.de/
Joined June 2017
  • Tweets572
  • Following236
  • Followers302
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The 3rd out of 4 publications honored with the 2024 medac Research Award shows how a novel gut-on-chip model simulates C. albicans infection and reveals how caspofungin alters fungal microcolony morphology and reduces pathogenicity. More in @Biomaterials_: doi.org/10.1016/j.biomateria…
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Happy to share our latest work in computational biology, published as research article in @CommsBio, on spatiotemporal modeling of the early immune mechanisms during fungal lung infections. Great collaboration between @MFIG_Bertuzzi's lab and @AppSysBio! nature.com/articles/s42003-0…
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The team from Jena @LeibnizHKI @UniJena bringing Candida, Aspergillus, Fusarium and Mucor to #HFP2024 🤩 w/ the groups of: @AmeliaBarberPhD @mgblango @Mark_Gresnigt @mpm_hki @AppSysBio (@hki_mi missing on photo)
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Replying to @Dynamic42_Jena
Hey, thank you for sharing! Here's a link to access the full version 😎 rdcu.be/dCnCq
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AppSysBio retweeted
AppSysBio@AppSysBio7 Mar 2024
You want to work on #image #based #systems #biology? - We want you! Please, send us your application as soon as possible: We have openings for two PostDoc and two PhD positions available! All info here: leibniz-hki.de/en/asb-newsde… Learn more about us here: asb.hki-jena.de/
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Automated image analysis with the ImageJ tool JIPipe jipipe.org of @AppSysBio #FungiNet @TRR_FungiNet
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I bet you got a 𝘨𝘶𝘵 feeling about @Raquel_Aloro and Parastoo's @AppSysBio talk on intestine-on-chip 𝘊. 𝘢𝘭𝘣𝘪𝘤𝘢𝘯𝘴 infection model at the #MicroverseSyposium2023 @microverse_exc. They are developing this model to, amongst other things, reliably evaluate antifungals.
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1⃣ #Postdoc #Researcher Position (m/f/d) in chemical ecology of marine microbial communities @PohnertL 2⃣ #Postdoc #Researcher Position (m/f/d) in Automated Bioimage Analysis @AppSysBio
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🔬Exciting Job Alert! Join our team as a Postdoctoral Researcher at @JSMC_Info🌱We're looking for passionate and innovative candidates who thrive on interdisciplinary collaboration. Apply by Aug 16th, 2023 👉microverse-cluster.de/en/job… #ResearchJobs #ScienceCareers

Jobs - Balance of the Microverse

microverse-cluster.de
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AppSysBio retweeted
SysMod@cosi_sysmod27 Jul 2023
Session 3: "Computational Modeling of Diseases" opened by Sandra Timme. Focused on using systems modeling to understand coinfections, her talk is titled: "Unraveling Complex Interplay b/w Acinetobacter baumannii & Staphylococcus aureus in Co-infections: #mathematicalmodeling
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The junior groups and @PStallforth are organizing this year‘s @LeibnizHKI summer party 🥳 @mgblango and @LuziaGyr moderated the games, the winner this time @AppSysBio 🥳🥳
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The MRC Centre for Medical Mycology is proud to announce the appointment of @judithberman11 as an Honorary Fellow. sites.exeter.ac.uk/medicalmy…
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Many thanks for a fantastic #NFDI4BIOIMAGE online Kick-Off yesterday! It's exciting & motivating to see so many consortium members, partners & guests from the #bioimaging community sharing a vision for improved #RDM 4 #microscopy as a part of @NFDI_de. Looking forward to more!
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Bacterial biofilms form on human immune cells: how? Why? 👇 cell.com/cell/fulltext/S0092… W/ @LuciaVidakovic @roi1avraham @alexpersat @MikhalevaSofya @HannahJeckel @KerstinMicrob

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

For the human pathogen Vibrio cholerae, biofilm formation is not only a protective trait but also an aggressive trait where biofilms form on immune cells, encase and kill them, and then disperse.

cell.com
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Replying to @notjustmoore
@notjustmoore giving an exciting talk about #zarr as a new standard file format at #elmi2023! … and showing what is going on today in the community room 👇👇👇 great that the community uses the room 🥰
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Josh Moore #openmicroscpy #Elmi2023 showing his brilliant skills not only as a stand-up presenter but as mastermind driving force behind ome-zarr @RoyalMicroSoc @GerBI_GMB @BioImagingUK @EuroBioImaging @afribioimagin @CTLSlifeScience
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The tuberculosis antibiotic BTZ-043 from Leibniz-HKI is Leibniz Drug of the Year! 🎉 It is currently the only new antibiotic from Germany that is being tested in clinical trials @LeibnizWGL @LMU_Muenchen @DZIF_ @BMBF_Bund @PanACEA_II @UNITE4TB @IHIEurope leibniz-hki.de/en/press-rele…

Leibniz Drug of the year 2023 is a tuberculosis antibiotic

The new antibiotic BTZ-043 has a completely new mechanism of action and belongs to a new class of substances. It i…

leibniz-hki.de
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A really cool and clever way of finding new biology: looking to ancient microbial genomes! From @PStallforth and @WarinnerGroup in Science
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Congrats to the entire team. After a very short time, a newly emerging scientific discipline reaches its first glorious climax. May many more follow. Transdisciplinarity pays off! @UniJena @JenaVersum @microverse_exc @chembiosys_jena @LeibnizWGL
Leibniz-HKI@LeibnizHKI4 May 2023
For the first time a team led by the department of Paleobiotechnology has successfully reconstructed molecules from DNA of bacteria from Stone Age dental calculus🥳@ScienceMagazine leibniz-hki.de/en/press-rele… @PStallforth @WarinnerGroup @WSS_Stiftung @MPI_EVA_Leipzig @Harvard_Press
A tooth wrapped in tin foil with dental calculus in several parts

ALT A tooth wrapped in tin foil with dental calculus in several parts

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Ready at @AppSysBio for our high school student guests today and tomorrow, for the #SchuelerTag organized at @LeibnizHKI . Lots of image analysis and modeling to amuse the students with.
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