@Andersonbuglab

Studying host-microbe interactions in the intestinal tract. Curious people are always welcome on our team. University of Edinburgh Wellcome Trust Funded

 Edinburgh, United Kingdom
andersonbuglab.com/
Joined March 2023
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  • Followers340
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We are thrilled to have @kodiravi speak at this inaugural event, and there is plenty of time to make it to the European Cell Death meeting with Ravi afterwards!
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Great opportunity for ECRs working on Cell Death. -6 October 2025 (CRUK Scotland Institute) -Registration is only £35 thanks to our sponsors! -Any attendee travelling from outside of Scotland is eligible for a travel award! -11 ECR speaking slots available + posters!
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Anderson lab retweeted
mBio@mbiojournal3 Feb 2025
This month, we're recognizing Dr. Zahra Islam for the highly rated reviews she has provided as an #mBio Early-Career Editorial Board member. Thank you for your valued contributions to the journal, @Zahra_F_Islam! @FertiliserHub Learn more about the ECB: journals.asm.org/journal/mbi…
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jobs.gla.ac.uk/job/research-… Excited to advertise this post-doc position in the Davidson Death Lab. Here, we'll live-image tumour cell death in diverse Drosophila tumour models to learn how different types of cancer learn to live with cell death.
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Interested in how hypoxia and critical illness shapes immune functions? Join the team! bit.ly/48KkLI7. Funded by a @wellcometrust CDA in @EdinUni_CIR

Postdoctoral Research Fellow

We are looking for a highly-motivated, creative and organised Postdoctoral Research Fellow to join the newly formed, Wellcome Trust-funded Mirchandani Lab within the Centre for Inflammation Research...

elxw.fa.em3.oraclecloud.com
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Our lab is looking for a postdoc with interest and experience in mucosal immunology and gut microbiome: nature.com/naturecareers/job…

Post-Doctoral Fellow: Gut microbiome and mucosal immunology - Esch-sur-Alzette (Canton) (LU)

The Post-Doctoral Researcher will work on ongoing and newly developed projects investigating host–microbiome interactions at the gut mucosa interfa...

nature.com
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Replying to @LarsVereecke @MaudeJans @magdalenakolata
Congratulations Lars, Maude, and the whole team! So happy to see this out.
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🎉 Super excited to announce that our study "Colibactin-driven colon cancer requires adhesin-mediated epithelial binding" is now published in Nature! Huge congratulations to first authors @MaudeJans and @magdalenakolata for their fantastic work! 1/6🧵🎉 nature.com/articles/s41586-0…
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October 2024 "Paper of the Month" Award 🏆: A really smart and thorough approach to microbial competition. High levels of translational potential while also significantly contributing to our fundamental understanding: win-win! nature.com/articles/s41586-0… @Nature

Commensal consortia decolonize Enterobacteriaceae via ecological control

Nature - Transplants of consortia with limited numbers of strains of commensal bacteria derived from healthy human stool samples are able to suppress intestinal Enterobacteriaceae by regulating...

nature.com
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September 2024 "Paper of the Month" Award 🏆 (slightly late 🤦‍♂️): A really interesting MiniReview on our strategies to define/classify and study dysbiosis. journals.asm.org/doi/full/10…. @ASMicrobiology

The human gut microbiome in health and disease: time for a new chapter? | Infection and Immunity

Advances in high-throughput sequencing in the first decade of the 21st century kicked off studies on host-associated microbial communities (the microbiota) using culture-independent approaches. By...

journals.asm.org
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Really excited to share our review in @NatRevImmunol, out today, on how oxygenation affects immune responses rdcu.be/dVzHA. A joint venture with @WalmsleyLab & @Man_Alex2012 Grateful for the editorial input from @Ybordon. @EdinUni_CIR
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Check out our new paper in @MicrobiomeJ on how dietary fiber metabolism modulates microbial-produced B vitamin availability in the gut and impacts the immune system. microbiomejournal.biomedcent…
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We are all living in a bubble that deprives us of experiences needed to understand the true magnitude of the threat posed by the rise of multi-drug resistant infections. It would be wise to allocate resources that match the severity of the threat. science.org/doi/10.1126/scie…

The coming microbial crisis: Our antibiotic bubble is about to burst

This month, the United Nations (UN) General Assembly will convene its second High-Level Meeting on antimicrobial resistance, urging UN member states to take decisive action against this growing...

science.org
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Replying to @MattOBurgess
Congrats @MattOBurgess! Fantastic work
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Conversation between host &gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy Preview of @Andersonbuglab @kodiravi work showing chemotherapy-induced apoptosis drives dysbiosis &transcriptional rewiring,delaying intestinal recovery cell.com/cell-host-microbe/a…
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September Featured Article: Interkingdom communication controls recovery following chemotherapeutic injury @Andersonbuglab @kodiravi cell.com/cell-host-microbe/f…
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Replying to @JustinPerryPhD @cellhostmicrobe @kodiravi @LarsVereecke @MDesai_Lab @CriscillaPhin
😂😂😂 there might be something out there on butyrate and efferocytosis that was in contention.
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This work started during my time with @kodiravi, who is an amazing mentor. The work evolved and blossomed into a wonderful international collaboration with @MDesai_Lab and @LarsVereecke who are fantastic collaborators. Huge thanks to the entire Anderson Lab and all co-authors!
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Really surprisingly, we found that death-dependent purine containing metabolites (AMP, GMP, IMP), can act as accessory signals to re-wire E coli transcription to promote aerobic respiration and suppress anaerobic respiration, even when grown under aerobic conditions (17% O2)!
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Intestinal epithelial cell apoptosis is necessary, though not sufficient, for chemotherapy-induced tissue damage and disease (mucositis). Further, the death-dependent bloom of E coli seems to be the missing link that connects cell death to disease.
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