@AndImaging

MPI for Multidisciplinary Sciences Fluorescent #probes for live-cell #nanoscopy: #STED, #MINFLUX and #confocal. We do the job, all of you judge if it is useful!

 Göttingen, Germany
mpinat.mpg.de/lukinavicius
Joined September 2018
  • Tweets928
  • Following4.4K
  • Followers3.4K
199Media
Chromatin labeling and imaging retweeted
The Nobel Prize
@NobelPrizeOct 5
BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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Detect and see chains of polyP! Our far-red fluorogenic SiX-DPA-Zn sensor detects inorganic polyP in cells, gels, in vitro assays & by STED microscopy. By @kenji_tori38197 & @GerasRuta JACS @ACSPublications doi.org/10.1021/jacs.6c14037
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PolyP probe SiX-DPA-Zn, BRIGHT Red signal, works in cells, gels, in vitro assays and STED microscopy. Now on @biorxivpreprint biorxiv.org/content/10.64898… . Congratulations to the authors @kenji_tori38197 and @GerasRuta . #ChemicalBiology #Fluorescence #Microscopy #Polyphosphate
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Chromatin labeling and imaging retweeted
Till Stephan@stephan_tillJun 14
📢 We are hiring! My lab is looking for a postdoctoral researcher. If you are excited about understanding cholesterol transport between the endoplasmic reticulum and mitochondria, membrane biology, lipid metabolism, or super-resolution imaging, please apply by June 30th!
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Make HDAC6 visible again! 6SiR-C3-NextA is a selective far-red probe for imaging endogenous HDAC6 in living cells across diverse mammalian cell types. Done by @Eyeshield_VN_21 Now in JACS @ACSPublications pubs.acs.org/doi/10.1021/jac…
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New preprint ! OptiFoot allows imaging of protein–nucleic acid interactions and places them into sequence context using Optical Genome Mapping, bridging super-resolution microscopy with single-molecule genomic analysis. #Genomics #Chromatin #Microscopy biorxiv.org/content/10.64898…
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Chromatin labeling and imaging retweeted
Nature Chemical Biology@nchembioApr 21
Illuminating microtubule architecture – Check out the associated News and Views by Rūta Gerasimaitė Gražvydas Lukinavičius nature.com/articles/s41589-0…

Illuminating microtubule architecture

Nature Chemical Biology - CenSpark, a dual-ligand fluorescent probe, enables selective live-cell imaging of centriolar and ciliary microtubule doublets and triplets across eukaryotes. By sensing...

nature.com
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Chromatin labeling and imaging retweeted
Nature Chemical Biology@nchembioApr 21
CenSpark is a dual-ligand fluorescent probe simultaneously binding inner and outer microtubule sites – a configuration unique to doublet and triplet microtubules, enabling selective live imaging of centrioles and cilia across species nature.com/articles/s41589-0…

Development of the fluorescent probe CenSpark for labeling centrioles and cilia

Nature Chemical Biology - CenSpark is a dual-ligand fluorescent probe binding simultaneously inner and outer microtubule sites, a configuration unique to doublet and triplet microtubules, enabling...

nature.com
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News & Views in @nchembio : CenSpark offers a new perspective on microtubule organization—moving beyond tubulin to capture higher-order structure in live cells. #AcademicPublishing #ResearchImpact #imaging nature.com/articles/s41589-0…
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Just published in @JACS_Au ! pubs.acs.org/doi/10.1021/jac… We show that the remarkable stability of proline-derived cofactors enabling efficient DNA labeling using methyltransferases—even under harsh conditions. Thanks to the contributors: @J_Bucevicius and @GerasRuta !
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New Year, New Microscope! We just got upgraded to Abberior MIRAVA POLYSCOPE — confocal → MATRIX → STED. First test looks good, large area and nice STED images using our probes. @Abberior @StefanHellLabs #microscopy #livecell #fluorescence #bioimaging
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New preprint! The remarkable stability of proline-derived cofactors opens efficient DNA labeling possibility using methyltransferases even at harsh conditions. biorxiv.org/content/10.64898… Congratulations to @GerasRuta and @J_Bucevicius . #Biochemistry #DNA #Fluorescence
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Wish all of You Merry Christmas and a Happy New Year!!! Enjoy AI-generated card for Chromatin labeling and imaging @AndImaging
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New preprint! We systematically evaluate red-shifted rhodamine-based DNA probes for in vivo chromatin imaging. Congratulations to Kamila and Shalini (@ShaliniPradha19) et al. Job done at @mpi_nat . Read more if you want to know which isomer is the best: biorxiv.org/content/10.64898… .
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We developed 6SiR-C3-NextA, a bright far-red, cell-permeable probe, enabling selective imaging of endogenous HDAC6 in living cells. Congratulations to Van-Thang Nguyen et al. (@Eyeshield_VN_21)! Developed at @mpi_nat and published on BioRxiv biorxiv.org/content/10.64898… .
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Celebrating 2nd PhD student of the group! 🎓 Van-Thang Nguyen (@Eyeshield_VN_21) from the Chromatin Labeling & Imaging group successfully defended his thesis through the @IMPRS_GS program at @mpi_nat. A smooth and impressive defense — and his paper is coming soon… 👀📄
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We have introduced a new biocompatible sulfonium-based building block for generation of non-cytotoxic covalent fluorescent probes. The proof-of-concept paper is out in @NatureComms : rdcu.be/eUn8F Great job done by @MarieAuvray4 at @mpi_nat !
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Happy DNA day!!! 😀 #DNA #Chromatin #research
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The updated Team of @AndImaging . We will keep you posted with our newest developments. Follow us: @J_Bucevicius @GerasRuta @GeorgijKostiuk @Eyeshield_VN_21 @D_Bubnyte @kenji_tori38197
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We have introduced a new biocompatible sulfonium-based building block for generation of non-cytotoxic covalent fluorescent probes. The proof-of-concept paper is on BioRxiv: doi.org/10.1101/2025.01.27.6… . Great job done by @MarieAuvray4 at @mpi_nat ! Enjoy reading!
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