@Amandality

Please find me on BlueSky @amandality.bsky.social Assistant Scientist @hfhs_bjc & Assistant Professor @michiganstateu

 Canada
Joined October 2011
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  • Followers623
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A degenerative disease of the joints, #osteoarthritis affects 50% of people over 65, with the biopsychosocial impact often overlooked. I'm grateful to be a part of the fight against this debilitating disease. xitter.cf/cihr_irsc/status/93516…
CIHR
@CIHR_IRSC27 Nov 2017
.@Amandality @UHN_News - A devoted granddaughter witnessed the decline of her grandmother due to #osteoarthritis and dedicated her career to finding a solution ow.ly/uO6W30gQ3qi #Canada150
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Monthly #OARSI ECI Publication: @Amandality and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target. Read the paper here: nature.com/articles/s41467-0…
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Excited to share our research on microRNA-126-3p in @NatureComms! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. rdcu.be/ebycj
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After almost 15 years, I'm moving! Please find me on BlueSky @amandality.bsky.social for all Ali Lab ongoings.
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When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #WomenInScienceDay: scim.ag/3WWWoSD
SCIENCESHOTS What does a scientist look like? Children are drawing women more than ever before

ALT SCIENCESHOTS What does a scientist look like? Children are drawing women more than ever before

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Dr. Amanda Ali retweeted
CIHR
@CIHR_IRSC11 Feb 2025
Today is the 10th International Day of Women and Girls in Science #IDWGS! Diversity in science benefits everyone! At CIHR, we’re proud to support women researchers at every career stage, including through programs like the REDI Award: cihr-irsc.gc.ca/e/53257.html…
International Day of Women and Girls in Science

ALT International Day of Women and Girls in Science

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Loving this Christmas gift from my lab 🎁 #AcademicTwitter #AcademicChatter
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Congratulations to Reshani, an outstanding DLSPH student @UofT_dlsph previously working with Osvaldo Espin-Garcia @WesternU, Jackie Whittaker @jwhittak_physio and I to better understand physical activity patterns in those with knee osteoarthritis.
Student and Recent Graduate Committee of the SSC@sscsargc16 Dec 2024
Reshani Abayasekara is the recent graduate of the month! 🎉 👩‍🎓 Reshani Abayasekara est la diplômée récente du mois!
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New publication alert! 📣 A team effort by Amanda Ali, Johanne Martel-Pelletier, & Osvaldo Espin-Garcia using integrated machine & deep learning to undercover microRNAs associated with knee osteoarthritis structural progression, now in @OACJournal here: authors.elsevier.com/c/1kDik…
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Comparison of definitions of early knee osteoarthritis for likelihood of progression at 2-year and 5-year follow-up: the Multicenter Osteoarthritis Study… “Most knees with early OA are stable and do not progress.” Nice work ⁦@rheum_cat⁩ et al.! ard.bmj.com/content/early/20…

Comparison of definitions of early knee osteoarthritis for likelihood of progression at 2-year and...

Background Preventing worsening osteoarthritis (OA) in persons with early OA is a major treatment goal. We evaluated if different early OA definitions yielded enough cases of worsening OA within 2–5...

ard.bmj.com
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Grateful to be part of such a stellar team alongside Osvaldo Espin-Garcia @WesternU working on methods to improve our interpretation of genetic and epigenetic traits associated with #osteoarthritis - find our recent publication in @OACJournal here: oarsiopenjournal.com/article…
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New publication alert! 📣 A collaboration to explore colocalization methods in osteoarthritis led by Osvaldo Espin-Garcia @WesternU and Amanda Ali @Amandality now published in @OACJournal - find it here: sciencedirect.com/science/ar…
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Dr. Amanda Ali retweeted
The Nobel Prize
@NobelPrize7 Nov 2024
Remembering the first woman to be awarded a Nobel Prize, the first individual to be awarded two Nobel Prizes and still today the only individual with two Nobel Prizes in two different scientific categories: Marie Skłodowska Curie. Curie was born #OnThisDay in 1867.
Cartoon illustration of Marie Skłodowska Curie. She is wearing a black dress and holding a laboratory glassware.

ALT Cartoon illustration of Marie Skłodowska Curie. She is wearing a black dress and holding a laboratory glassware.

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Restricting sugar exposure in the first two years of life can meaningfully reduce the risk of chronic diseases in adulthood. We need to rethink many cereals, snacks, and treats for children. science.org/doi/10.1126/scie…

Exposure to sugar rationing in the first 1000 days of life protected against chronic disease

We examined the impact of exposure to sugar restrictions within 1000 days after conception on type 2 diabetes and hypertension, leveraging quasi-experimental variation from the end of the United...

science.org
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Did you know that ~50% of people that have a knee injury will develop #osteoarthritis within ~10 years? More importantly did you know there are things you can do about it? @soarknee @Aging_SMART @Arthritis_ARC
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Just three weeks until our application deadline! We offer a unique fellowship that can have a direct impact on mental health care! DMs are open for questions!
Jordan Braciszewski@jmbrockphd3 Sep 2024
Looking for a fellowship that provides grant writing training, dozens of dedicated mentors, the ability to directly impact health care, and 3+ days/week of independent time to pursue your own work? Check out our NIMH-funded T32 fellowship in mental health services research. Link:
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The 2024 Nobel prize in physiology or medicine has been awarded to Victor Ambros and Gary Ruvkun, who discovered microRNAs, a class of tiny RNA molecules that help to control how genes are expressed in multicellular organisms. Read the @Nature article. go.nature.com/3BwBsKt

Medicine Nobel awarded for gene-regulating ‘microRNAs’

Nature - Victor Ambros and Gary Ruvkun identified a class of tiny molecules that have a crucial role in controlling gene expression.

nature.com
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Dr. Amanda Ali retweeted
The Nobel Prize
@NobelPrize7 Oct 2024
Congratulations to our 2024 medicine laureate Victor Ambros ✨ This morning he celebrated the news of his prize with his colleague and wife Rosalind Lee, who was also the first author on the 1993 'Cell' paper cited by the Nobel Committee. #NobelPrize
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The Nobel Prize in Physiology or Medicine 2024 - NobelPrize.org ... jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation! I'm privileged to be studying the role of #microRNAs in #osteoarthritis.
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Dr. Amanda Ali retweeted
Reviewer 2@GrumpyReviewer224 Sep 2024
#AcademicChatter #AcademicX
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Heads us up that CIHR @CIHR_IRSC is welcoming applications for Scientific Director of CIHR-IMHA ... (link below) ...
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