@AliHermanlab

studying #vascular #senescence and #aging at the NIA/NIH | all tweets and views are my own |

 Baltimore, MD
Joined January 2022
  • Tweets90
  • Following400
  • Followers384
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Can VSMC senescence be a reversible phenotype? Our review explores if senescent VSMCs are an intermediate VSMC state. @alihermanlab @em_maragkakis @katarinagresova ahajrnls.org/3JWjo10
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Super cool presentations today by @ana_cujba @AliHermanlab, Amber Stratmann and @mahak906! Circadian biology, senescence, cilia and many more new exciting topics in this morning session!
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1/ No, you do not always need single-cell RNA-seq. Here's why bulk RNA-seq might still be the smarter move for your experiment.
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So much to celebrate this week! Our first original research paper was published, we welcomed our new postbac, Ted, and said goodbye to our longest tenured lab member and postbac Charnae' who is off to Georgetown for her Master's! I am very proud of this group 🥳
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We are migrating to Blue Sky! Come join the party 🎉😅 bsky.app/profile/alihermanla…
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My lab has been working for the past 15 years to develop a method to isolate specific genomic loci to identify its chromatin composition & protein interactome. Finally,… our superb physician/scientist Dr. Bercin Cenik @bkcenik did it and here it is cell.com/molecular-cell/full… Not only was she able to develop this method, which she calls TurboCAS, she was able to identify known & novel regulators of heat shock & Myc expression. Cannot wait to see what Bercin and TurboCAS will discover about the molecular basis of transcriptional regulation with great impact on clinic in the next few years! @NU_BMG_SQE @NUFeinbergMed @MolecularCell
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VABU field trip to see #Wicked for our holiday outing! We loved it 💚🩷
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A comprehensive review on cellular #senescence, highlighting up-to-date mechanisms and interventions. A must-read resource for advancing #aging research.👇 nature.com/articles/s41514-0… Great work by @flor_herbstein, @Smorsli_ & rest of yICSA board members.
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Really interesting study from @hagayanay and the Beerman lab 👇🏻👏🏻
Isabel Beerman@BeermanHSCaging15 Oct 2024
Congratulations to @hagayanay a fantastic postdoc on the job market: showed HSC divisional history is tracked by DNA methylation and correlates with function. Also beautifully resolves an outstanding question regarding DNA damage and HSC aging rdcu.be/dW3sC
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🚨Postdoc Opportunity🚨 Join the Brain Health Equity Unit @ NIA to study brain health disparities in historically marginalized communities, using neuroimaging, genomics & epidemiology. Apply by 10/4/24: training.nih.gov/jobs/pdp-10… #Postdoc #BrainHealth #HealthDisparities #ScienceJobs
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Very happy to have this out! In this study we show that the DNA modification, 5hmC, increases over bodies of tissue-specific genes in the aging liver and serves a function different from DNA methylation. Congrats @occean_james! nature.com/articles/s41467-0…

Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging

Nature Communications - DNA hydroxymethylation (5hmC) is typically altered in age-related diseases. Here, the authors show that 5hmC accumulates in gene bodies, partially due to prolonged...

nature.com
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We are hiring a postbac fellow! The focus will be vascular aging in mice, with the ability to learn other skills such as cell culture and molecular biology techniques! Please DM or send to anyone interested
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Thanks so much to all who shared and expressed interest. Unfortunately this position can only be filled by a US citizen at this time.
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Once again, we are grateful and elated to see AGE supporting our trainees! We are so proud of Ada and all that she has accomplished so far, with much more to come! Check out Ada’s poster if you are attending #AGE2024 next week!
American Aging Association
@americanaging27 May 2024
Congratulations to Ada Okereke, one of our 2024 AGE Diversity Award winners! Ada is a postbaccalaureate researcher at @NIHAging @NIH who studies how long noncoding RNAs influence cellular #senescence. #AGEDiversity #AGETC #AGE2024 #WomeninSTEM
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It will be hard to top this year’s meeting but I can’t wait to take everyone to the best places for crabs, crab cakes, and pit beef! 🦀 See you in Baltimore 🦀
AHA Science
@AHAScience18 May 2024
That’s a wrap for #VascularDiscovery24. Let’s do it again next year. See you in Baltimore!
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Our new lab, the Vascular Aging Biology Unit, opens this June and we are looking for postdocs who are interested in studying the vascular senescent cell surfaceome and vascular aging and its relationship with cognitive decline. Please DM if interested, and RT to share
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This study has laid the groundwork for the research directions in the #RasheedLab @ImmunologyAU (we are looking for postdocs to work on these projects 🚨🚨) augusta.edu/centers/immcg/ad… 10/

Adil Rasheed, PhD

augusta.edu
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Arrived with perfect timing to learn new omic strategies to identify senescent cells! Great talk by Allison B Herman #VascularDiscovery24 @AHAScience
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The lab heads to Chicago in one week for #VascularDiscovery24! Who else is excited? 🙋‍♀️🙋‍♂️
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We are so proud of Tatiana! Thank you @americanaging for recognizing and supporting young, enthusiastic scientists like Tati! Check out her poster if you are going to #AGE2024
American Aging Association
@americanaging1 May 2024
Introducing Tatiana Rodriguez, one of our 2024 AGE Early Career Scholars! Tatiana works on vascular aging and cellular senescence @NIHAging @NIH. Congratulations Tatiana! #AGEScholars #AGETC #WomeninSTEM #AGE2024
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