@AlexH_UB

PhD Student @UniBonn | Bioinformatics & Bioengineering with @schmidburgk

 Bonn
github.com/AlexH-UB
Joined January 2015
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  • Following96
  • Followers22
Can AI-designed binders degrade, aggregate, stain and enrich endogenous proteins in human cells? Check out our new preprint! biorxiv.org/content/10.1101/…

Transposon-Display of AI-designed binders enables manipulation of the proteome in human cells

Transposon-Display is a highly scalable screening method that links proteins to their encoding DNA during expression in E. coli via a mutant transposase. Leveraging this system, we identified...

biorxiv.org
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Alles Gute zum #Stiftiäum! Die #Studienstiftung feierte heute ihren 100. Geburtstag in ihrer Ursprungsstadt Dresden. BM @cem_oezdemir gratulierte persönlich und stellte die Bedeutung von #Begabtenförderung heraus, gerade auch für die Chancen- und Bildungsgerechtigkeit.
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Nature research paper: RNA control of reverse transcription in a diversity-generating retroelement nature.com/articles/s41586-0…
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How could we identify key genes involved in any biological process and cell type? Please read on about Nuclear In-Situ Sequencing (NIS-Seq) nature.com/articles/s41587-0…

NIS-Seq enables cell-type-agnostic optical perturbation screening

Nature Biotechnology - An optical pooled screening method can correlate phenotypes and perturbations in any nucleated cell type.

nature.com
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NIS-Seq enables cell-type-agnostic optical perturbation screening go.nature.com/3P35toD
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It was a great pleasure for us to welcome you for two weeks from the University of Bonn 🇩🇪 Thank you so much!
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Brain of fly to shed light on human thought process bbc.in/4ePnhPc
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Had to get one for the lab. #Falcon your falcon! Printed by @gha14 Instructions: thingiverse.com/thing:273887…
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Tutorial lecture by Prof. Jonathan Schmid-Burgk (Bonn University) was held at TWIns. Thank you very much!
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1/8 How can we enrich cells with a defined transcriptional state, but without killing them? Please read on! biorxiv.org/content/10.1101/…

Sensing endogenous RNA in living human cells using a CRISPR-activated protease

Most techniques used to detect specific mRNAs in eukaryotic cells require to extract nucleic acids and thereby kill the cells. A programmable sensor for monitoring endogenous transcripts in living...

biorxiv.org
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