@AlanHanash

Bone Marrow Transplant Physician-Scientist

New York City
Joined September 2012
Thank you @JustinPerryPhD, @David_Lab_MSK, and especially @parkerici! We are so excited about the opportunity and grateful for the support!
Thanks to the @parkerici for funding a Career Development Award for the Perry Lab @sloan_kettering . Congrats to fellow recipients @David_Lab_MSK and @AlanHanash . We are all super grateful!
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Immune cells target #stemcells in the destruction of intestinal lining cells that occurs before renewal. Research by @AlanHanash @sloan_kettering in @SciImmunology. Read more on bpod.mrc.ac.uk/archive/2020/… with @MRC_LMS and @AntDLewis
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Being a physician scientist is immensely rewarding. I come to the lab/clinic every day with a sense of wonder, joy, and anticipation. I support these efforts to keep this career path at the nexus of investigation and patient care alive. Pay it forward. nytimes.com/2019/09/23/opini…
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Alan Hanash retweeted
7/10 PATHOPHYSIOLOGY: @AlanHanash and colleagues showed that IFN-g directly programs intestinal stem cells for apoptosis, and that the effect can be reversed by neutralizing Abs or JAK/STAT inhibition. Rux may influence tissue responses to inflammation. immunology-sciencemag-org.ez…
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Outstanding playlist! Very honored to be included.
Replying to @ejvillablanca
In 2012, @AlanHanash published that IL-22 protects intestinal stem cells from immune-mediated damage in our interest turned into this cytokine as a potential therapeutic strategy to promote #mucosal #healing in #IBD patients. DOI: 10.1016/j.immuni.2012.05.028
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Still time to vote for December cover highlighting work by @sloan_kettering @AlanHanash on immune-mediated damage of intestinal stem cells – at Manhattan, NY
Replying to @SciImmunology
Vote for one of the three covers displayed above to help select Science Immunology's 2019 “Cover of the Year."
28%Jan. Nuclear F-Actin
47%Jun. Lung ILC2s
25%Dec. Stem Cell Ribbons
314 votes • Final results
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Alan Hanash retweeted
Clearly stem cell ribbons from December, right @AlanHanash ?
Congratulations to 3 finalists in 2019 #CoveroftheYear contest. All 3 images contributed by @SciImmunology authors. Vote for your favorite in our grand finale 7-day poll. Feel free to retweet this post to encourage wide participation. Poll ballot is in 2nd tweet in this thread.
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Vote for one of the three covers displayed above to help select Science Immunology's 2019 “Cover of the Year."
28%Jan. Nuclear F-Actin
47%Jun. Lung ILC2s
25%Dec. Stem Cell Ribbons
314 votes • Final results
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Alan Hanash retweeted
New article on pre-transplant serum levels of claudin-3 as a predictive biomarker for intestinal #GvHD and non-relapse mortality risk in patients undergoing allo-HSCT, now available on the @gvhd_hub ➡️ buff.ly/2sIu3Et #bmtsm
Choose your favorite of 4 covers displayed above to pick the third finalist for Science Immunology's 2019 "Cover of the Year."
6%Sep. Skin Treg Mirroring
13%Oct. ILC3s & Clock Genes
30%Nov. Measles Zaps B Cells
51%Dec. Stem Cell Ribbons
67 votes • Final results
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Organoids in immunological research dlvr.it/RLWh3L
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The MSK Infectious Disease Service is recruiting a new clinical faculty member. Please apply if interested in joining a terrific faculty in New York City.
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Many examples of T cells causing pathology in the gut during infection and role of IFN-g (best cytokine ever). How does IFN-g contribute? See cool paper on T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage immunology.sciencemag.org/co…
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Happy to be home in sunny NYC. Thanks to our amazing speakers @zhangf, Giuliana Ferrari, and Wendell Lim for making transplant/cellular therapies the best scientific session at #ASH2019 and one of the most attended!
Great discussion at the annual meeting of the #ASH19 Scientific Committee on Transplantation Biology and Cellular Therapies! This year our session #ASH2019 attracted more than 500 colleagues! Great job @AlanHanash, Cathy Wu, @MarcoLDavila @MarcelaMaus and many more!
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Antonio Gomes @sloan_kettering: normal gut microbiome diversity predominates pre-BMT. Pip/tazo tends to perturb this in favor of Step and Enterococcal spp. that can assoc w ⬇️survival. Higher fat diet and cefepime may help support high microbiome diversity. #ASH19
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Awesome collaboration. Human #organoid work studying immunology of #stemcells performed by @clindemans lab at @UMCUtrecht!
Using human intestinal #organoids, Dr. @AlanHanash's lab found that intestinal stem cells can be directly targeted by T cell-derived cytotoxic cytokine signaling. @SciImmunology bit.ly/2DQ5szY
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Another Year in Review to add to our series covering the hottest developments in immunology in 2019. This one is from Lionel Ivashkiv on the hypoxia-lactate axis in inflammation @ivashkivlab go.nature.com/2Pt3sD2
We’ll always have Orlando
And with a final day @vandenBrinkLab reunion dinner, that’s a wrap for me at #ASH19 @AlanHanash @RobJenqMD @clindemans (missing, @DrMvandenBrink)
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