Laboratory of Dritan Agalliu, Ph.D. neuroimmunology / vascular biology / blood-brain barrier biology / neuroscience - account run by lab members
Columbia University
Joined November 2019
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- Following444
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Agalliu Lab retweeted
I just received the news that the Board of Trustees at @Columbia University in the City of New York approved my promotion to Full Professor with Tenure. I’m very happy and thankful to the members of the @AgalliuLab for their hard work! Let’s keep doing good science!
Agalliu Lab retweeted
Out in @Cell today: In a collaborative effort across multiple labs, we found that cMAF controls the identity and function of perivascular macrophages critical for cerebrovascular function.
cell.com/cell/fulltext/S0092…
A thread:
The @AgalliuLab is so proud of both. @CharlotteRWayne (Charlotte Wayne) and @occludens (Ugur Akcan) for their hard work to get this amazing paper out! We also thank our donors, in particular @PANDASnetwork for continuing to support our research on PANDAS and Sydenham’s chorea.
GROUNDBREAKING Research Columbia Univ., Mechanisms of PANDAS & Sydenham's chorea.
Principal investigator Dritan Agalliu, Ph.D.Chair of the PANDAS Network Scientific Advisory Board and Postdoctoral Research Fellow Ugur Akcan PhD, and Charlotte Wayne have worked to understand how streptococcal bacteria underlie the acute encephalitic onset in children with PANDAS and Sydenham's chorea.
Read about it in our newsletter
pandas-network.kit.com/posts…
We need to develop a universal vaccine for Group A strep too, not just Group B, as it triggers a lot of secondary sequelae including neuropsychiatric ones.
Scientists are one step closer to developing a universal vaccine against the bacterium that causes pneumonia and meningitis
go.nature.com/4wlW5Q9
Agalliu Lab retweeted
Our back to back paper @NatureNeuro is out today (rdcu.be/fzGg0). We developed a method to visualize ribosomes bound to endogenous mRNAs with near codon resolution and made some really counterintuitive cell biological discoveries which have cool implications for AD🧵
Agalliu Lab retweeted
I want to thank @CharlotteRWayne (Charlotte Wayne) and @occludens (Ugur Akcan) for their amazing work to complete this paper that took 3 years in revision. Thanks to many collaborators too.
Agalliu Lab retweeted
We here show that Group A Strep infections trigger profound changes in the transcriptome of microglia and BECs. Distinct Th17-derived cytokines have shared and unique effects on these cells. Microglia activate many cytokines that are also found elevated in patients with PANDAS.
Agalliu Lab retweeted
Finally, it is official! Our paper describing how microglia and brain endothelial cells respond to repeated Group A Strep infections and the implications for Sydenham’s chorea and PANDAS is out in Nature Communications. nature.com/articles/s41467-0…
Agalliu Lab retweeted
PPN welcomes Dr. Jennifer Frankovich as our new Chief Science Officer. Her leadership and expertise will advance scientific initiatives, research priorities, and resources that support diagnosis and care for individuals with PANS/PANDAS. pandasppn.org/cso-jennifer-f…
Agalliu Lab retweeted
Good luck Aomeng Cui finishing your medical degree at Columbia University Irving Medical Center! ♥️♥️
Agalliu Lab retweeted
A wonderful dinner celebration at Giardino 45 with members of the @AgalliuLab and Sproul lab to celebrate the successful PhD dissertation of our amazing student Aomeng Cui. She led the study that generated a novel iPSC-based neurovascular unit using the 3D MIMETAS platform.
Agalliu Lab retweeted
🎓 Mark your calendars! On May 20, NYC’s iconic @EmpireStateBldg will glow Columbia Blue to celebrate our #Columbia2026 graduates.✨
Get the details on the best spots to take grad photos with the Empire State Building: news.columbia.edu/news/when-…
📷 Empire State Building image® by David Dini
ALT The image shows the New York City skyline at night, with the Empire State Building prominently lit in blue against a backdrop of other illuminated skyscrapers. The sky appears cloudy or foggy.
Agalliu Lab retweeted
Thanks to the amazing work of Ugur Akcan @occludens we discovered that the autoantibodies targeting the BBB in schizophrenia patients, break down the BBB.
Agalliu Lab retweeted
The study suggests that schizophrenia has an immune component supporting the role of an aberrant immune response as a trigger for a neuropsychiatric disorder. This has similarities to our findings with post-streptococcal encephalitis (PANDAS).
Agalliu Lab retweeted
I am very excited to be part of the study entitled “High prevalence of CNS-directed autoantibodies in patients with schizophrenia” which outlines the identification of many autoantibodies, including those targeting the BBB in schizophrenia patients.
biorxiv.org/content/10.64898…
Agalliu Lab retweeted
I’m excited to announce that this collaboration with the Konofagou laboratory to examine the cell biological mechanisms and transcriptome changes at the BBB after Focused Ultrasound with Microbubbles-mediated BBB opening is now published.
nature.com/articles/s44172-0…
Agalliu Lab retweeted
Drs. Dritan Agalliu (Columbia), Madeleine Cunningham (Univ of OK), Russell Dale (Univ of Sydney, AU), & Jennifer Frankovich (Stanford) present their research & discuss whether PANS & PANDAS are best understood as autoimmune, autoinflammatory, or both. ➡️pandasppn.org/neuroimmune-ep…
Agalliu Lab retweeted
Finally - It is official. Thank you @atvbahajournals for highlighting the amazing work of Aomeng Cui in the @AgalliuLab and Sproul labs to generate IPSC-derived human brain endothelial cells and build a 3D iPSC - derived neurovascular unit for studying neurological diseases.
Cui et al, describe the generation of human iPSC-derived BMECs using transcriptional
reprogramming with strong BBB features for modeling neurological disorders @DAgalliu
ahajrnls.org/3KHeF3p
Agalliu Lab retweeted
Breakthroughs happen many times when you're able to re-imagine your project as a different form of puzzle.
NYC Postdocs: Join us on Wednesday at Columbia University for this exciting Night Science session on puzzle switching! Registration is free and we have a few spots left.
NYC Postdocs: Join us for our next Postdoc Night Science NYC session, when we will practice how to get new ideas using "puzzle-switching"! This time we're in Columbia (Morningside Campus) on Dec 3rd at 5PM.
Free registration: docs.google.com/forms/d/1onf… @StearnsLab @KelseyRMonson
