@ASBrumm

PostDoc in the Lowell lab @EdinUni_IRR @_CellySally_, previously PhD @TheCrick @NiakanLab.

Joined July 2024
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Replying to @Dev_Cell
And if you're interested in the details of detecting and quantifying phosho-SMAD protein expression, check out our methods paper, online today at @STARProtocols. Thanks again to my outstanding co-authors @toddfallesen.bsky.social and the @NiakanLab. sciencedirect.com/science/ar…
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Congratulations to our Editor-in-Chief @briscoejames on receiving the BSDB Waddington Medal. He has made a big impact on @Dev_journal since becoming EiC in 2018, including introducing Associate Editors, launching the Pathway to Independence programme & developing the Node Network
James Briscoe presenting in front of an auditorium.

ALT James Briscoe presenting in front of an auditorium.

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We are starting ✨2026✨ strong with our first Western 🌙 Session: 📅8th Jan ⏰ 17:30 GMT With: Jan Jakub Zylicz🐭👩‍🔬 👉Epi-metabolic regulation of early development Anahi Binagui-Casas🐭👩‍🔬 👉Studying the lineage potential of in vitro derived neuromesodermal progenitors
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Excited to talk about my new project on neighbour labelling in neuromesodermal progenitors at @Co_Biologists, poster 165.
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Dr @GunesTaylor is the editor of our magazine and clearly a fan of science since an early age! This is what she would share with a videoscope-loving young Gunes! #InternationalDayofWomenandGirlsinScience #WomenInScience
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The next extraordinary biologist is Anahí Binagui-Casas, an early-career researcher involved in the Biologists @ 100 conference and her research focusses on vertebrate development . #100biologists Register for the conference at 100yearsconference.biologist….
The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Binagui-Casas to the left, text to the right 100 extraordinary biologists Anahí Binagui-Casas Anahí Binagui-Casas is a BSDB early-career representative involved in the Biologists @ 100 conference and a Development Travelling Fellowship awardee. She participated in the 2020 Workshop on human birth defects and investigates vertebrate development at The University of Edinburgh. #100biologists #biologists100

ALT The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Binagui-Casas to the left, text to the right 100 extraordinary biologists Anahí Binagui-Casas Anahí Binagui-Casas is a BSDB early-career representative involved in the Biologists @ 100 conference and a Development Travelling Fellowship awardee. She participated in the 2020 Workshop on human birth defects and investigates vertebrate development at The University of Edinburgh. #100biologists #biologists100

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Establishment of feline embryonic stem cells from the inner cell mass of blastocysts produced in vitro pubmed.ncbi.nlm.nih.gov/3969…

Establishment of feline embryonic stem cells from the inner cell mass of blastocysts produced in...

We successfully established three feline ESC lines, each possessing pluripotent potential and capable of differentiating into all three germ layers, derived from the inner cell masses of blastocysts...

pubmed.ncbi.nlm.nih.gov
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❗ANNOUNCEMENT❗ YEN 2025 Conference will be held at @TheCrick on the 19th May 2025. We have an exciting line-up with Nicolas Rivron, Maud Borensztein and Peter Rugg-Gunn. This year will see a return of the YEN Image Competition so follow for updates. Share for #YEN2025!
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#DBfeature “When does human life begin?” teaching human embryology in the context of the American abortion debate “There is no consensus among biologists as to when an independent human life begins” by Scott Gilbert sciencedirect.com/science/ar…
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Congratulations to Prof. Kathy Niakan, @NiakanLab, on being awarded the Mary Lyon Medal🏅 for their pioneering research on the function of genes that regulate early human development and the molecular mechanisms that direct cell fate in human embryos. genetics.org.uk/medals-and-p…
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Beyond thrilled to share my PhD work, published yesterday in @Dev_Cell. We show that both NODAL and BMP signalling are active in the human blastocyst, but NODAL signalling is not required to initiate or maintain the human pluripotent epiblast. 1/10
Developmental Cell@Dev_Cell19 Nov 2024
Online now: Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling dlvr.it/TGFtBj

Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is...

Brumm et al. find that NANOG expression in the human epiblast precedes NODAL signaling activity. NODAL signaling inhibition did not impair formation of human epiblast or primitive endoderm cells,...

cell.com
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Finally, if you fancy a deep dive into our data, over 100GB of confocal microscopy data on human blastocysts are available at ebi.ac.uk/biostudies/bioimag…. 10/10

BioStudies < The European Bioinformatics Institute < EMBL-EBI

BioStudies – one package for all the data supporting a study

ebi.ac.uk
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Special shout-out to @MicheleMarass , our outstanding steward through the turbulent waters that is the review process.
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