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Experts dedicated to prioritizing, designing, and executing clinical research that will reduce the public health threat of antibacterial resistance.
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ALT A R L G Grand Rounds Recording: Innovations in Diagnostic Trials. Michael Satlin, MD, Weill Cornell Medicine; Sarah Doernberg, MD, MAS, UC San Francisco; Ritu Banerjee, MD, PhD, Vanderbilt University. Moderator: Robin Patel, MD, D(ABMM), FIDSA, FACP, F(AAM), FAAAS, Mayo Clinic. A R L G - Antibacterial Resistance Leadership Group
ALT A R L G Member Spotlight: Associate Director, Laboratory Center, Sarah Doernberg, MD, MAS, Professor of Clinical Medicine, University of California, San Francisco. "Caring for patients with compromised immune systems, I witness the impact of antimicrobial-resistant infections frequently. High quality, informative clinical research that advances and informs the diagnosis and treatment of these infections is critical."
ALT A R L G DOOR Endpoint for Acute Bacterial Skin and Skin Structure Infections Featured in Open Forum Infectious Diseases. Editorial, "What's Behind DOOR Number 2? Recent Applications From Post-Hoc Analyses of Infectious Diseases Randomized Clinical Trials." A R L G - Antibacterial Resistance Leadership Group
ALT Manuscript Published in Open Forum Infectious Diseases, "Development and Application of a Desirability of Outcome Ranking (DOOR) Endpoint for Acute Bacterial Skin and Skin Structure Infections," Howard-Anderson J, Hamasaki T, Ge L, et al. DOOR Level infographic: A scale of 1 to 5 ranging from dark green (1 = best) to bright red (5 = worst). 1 = 0 Events, 2 = 1 Event, 3 = 2 Events, 4 = Greater than or equal to 3 Events, 5 = Death. *Events include: lack of improvement with the treatment; a different problem caused by the original infection; an unwelcome event which is life-threatening or leads to a longer hospitalization or significant disability.
ALT Congratulations! Vance Fowler, MD, MHS, Florence McAlister Distinguished Professor of Medicine, Professor of Molecular Genetics and Microbiology, Member in the Duke Clinical Research Institute. 2026 Hamao Umezawa Memorial Award, International Society of Antimicrobial Chemotherapy. A R L G - Antibacterial Resistance Leadership Group - a r l g .org
ALT Manuscript published in mBio. A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol. Kawai A, McElheny CL, Shields RK, et al. A R L G, Antibacterial Resistance Leadership Group.
ALT Congratulations! Ahmed Babiker, MBBS, MSc; Assistant Professor, Department of Internal Medicine, Division of Infectious Diseases; Rush University; A R L G Early Faculty Seedling Award Recipient. Top Featured Oral Abstract, Society for Healthcare Epidemiology of America (SHEA) Spring 2026 Conference. A R L G, Antibacterial Resistance Leadership Group, arlg.org
ALT Manuscript published in Antimicrobial Agents and Chemotherapy. Resistance to novel β-lactam/β-lactamase inhibitors among carbapenem-resistant Pseudomonas aeruginosa and clinical implications in the prospective observational Pseudomonas study. Gottesdiener LS, Li Y, Greenwood-Quaintance KE, et al. A R L G, Antibacterial Resistance Leadership Group