@ARLGnetwork

Experts dedicated to prioritizing, designing, and executing clinical research that will reduce the public health threat of antibacterial resistance.

Joined September 2019
The #ARLGnetwork FAST trial evaluated rapid vs. standard antimicrobial susceptibility testing for gram-negative bloodstream infections. Read the results and check out the highlights in a @JAMAnetwork editorial, podcast, and research summary🔗arlg.org/fast-jama
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✅Study Milestone: Enrollment has closed for #ARLGnetwork OPTIMIZE-GNI, a Phase IV study of cystatin C–guided beta-lactam dosing in critically ill adults with suspected or documented #AMR Gram-negative infections. Learn more about ARLG research🔗arlg.org/arlg-studies
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▶️The #ARLGnetwork Innovations in Diagnostic Trials recording is now available! Presented by Drs. Michael Satlin @WeillCornell, Sarah Doernberg @UCSFHospitals & Ritu Banerjee @VUMCDiscoveries & moderated by Dr. Robin Patel @MayoClinic🔗arlg.org/grand-rounds-diagno…
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In this #ARLGnetwork member spotlight, Sarah Doernberg, MD, MAS, @UCSF, a longtime ARLG investigator & mentor, shares how her work in diagnostics, treatment, antimicrobial stewardship, & patient-reported outcomes supports the fight against #AMR🔗arlg.org/sarah-doernberg-md-…
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How can RCTs better reflect what matters most to patients? An editorial in @OFIDJournal highlights the #ARLGnetwork’s application of the Desirability of Outcome Ranking (DOOR) framework to trials in acute bacterial skin and skin structure infections🔗 arlg.org/door-absssi-ofid
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An #ARLGnetwork study in @OFIDJournal applies the DOOR method to trials in acute bacterial skin and skin structure infections (ABSSSI), offering a patient-centered benefit-risk framework that may add perspective beyond traditional clinical outcomes🔗duke.is/ARLG-publications
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How do patients and clinicians describe the impact of complicated UTIs on quality of life? An #ARLGnetwork study in @JAMANetworkOpen highlights gaps that could inform patient-centered trial outcomes & improve patient-clinician communication🔗duke.is/ARLG-publications
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🔦New #ARLGnetwork clinical trial site spotlight: Dr. Natalie E. West & her research team @HopkinsMedicine supported PHAGE, a clinical trial exploring bacteriophage therapy for people with #CysticFibrosis & chronic Pseudomonas aeruginosa infection🔗arlg.org/site-jhu
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Congratulations to #ARLGnetwork Co-PI Vance Fowler, MD, MHS, recipient of the @ISAC_world 2026 Hamao Umezawa Memorial Award, ISAC’s highest honor for contributions to antimicrobial chemotherapy. Dr. Fowler will deliver the award plenary at ICC 2026🔗arlg.org/vance-fowler-isac-a…
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📣 Due Aug. 28 – Attendance grant apps for @ESCMID postgrad course on clinical trials. The course will be led by #ARLGnetwork members Drs. Angela Huttner, Thomas Holland, and @davidantibiotic with other experts in #InfectiousDiseases and #Microbiology🔗arlg.org/escmid-course
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The #ARLGnetwork PROOF study investigated the pharmacokinetics, safety & side effects of 2 dosing regimens of fosfomycin, a treatment for UTIs. This research can help doctors choose dosing regimens that are safe & appropriate for their patients. Learn more duke.is/ARLG-PROOF
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The #ARLGnetwork PROVIDE study found the ideal vancomycin range to target on day 2 of treatment to maximize effectiveness while reducing the risk of kidney injury, improving the care of adults hospitalized with MRSA blood infections. Learn more: duke.is/ARLG-PROVIDE
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The #ARLGnetwork MASTER-GC study assessed 3 tests for diagnosing gonorrhea & chlamydia in the throat & rectum. Results led the FDA to approve the first tests for this use, expanding options for accurate detection and improving treatment. Learn more: duke.is/ARLG-MASTER-GC
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Overuse of antibiotics in U.S. community hospitals can lead to superbugs & higher healthcare costs. The #ARLGnetwork DICON study showed that targeted training for hospital pharmacists may help improve antibiotic use. Learn more: duke.is/ARLG-DICON #AntibioticStewardship #AMR
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The #ARLGnetwork’s Drs. Angela Huttner, Tom Holland, & @davidantibiotic will join other experts in #InfectiousDiseases & #Microbiology in leading a 3-day @ESCMID postgrad course to train new researchers in all phases of clinical trials🔗duke.is/ARLG-ESCMID-course-2
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In @JAMANetwork: #ARLGnetwork FAST trial evaluated rapid v standard antimicrobial susceptibility testing for gram-negative bloodstream infections. Rapid testing wasn’t superior for day-30 outcomes but may help inform antibiotic decision-making in practice🔗duke.is/ARLG-pub-FAST
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How can evidence generation for priority antibiotics better support both regulatory approval & clinical use? The @WHO #AMR Department is hosting a meeting to discuss global antibiotic development: 📅 31 August 🕑 14:00–16:00 CET 🔗 Learn more & register: shorturl.at/95AwM
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📄New #ARLGnetwork pub in @mbiojournal: Researchers identified a mutational hot spot in ADC β-lactamase that reduces susceptibility to advanced β-lactam agents in carbapenem-resistant Acinetobacter baumannii, reinforcing the need for ongoing surveillance🔗duke.is/ARLG-pub-ADC
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Congratulations to Ahmed Babiker, MBBS, MSc, #ARLGnetwork Early Faculty Seedling Award recipient! His innovative research on FMT & MDRO decolonization was recognized as a Top Featured Oral Abstract at SHEA Spring 2026. Learn more about his work🔗duke.is/ARLG-Ahmed-Babiker-M…
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📄An international #ARLGnetwork POP-MDRO study examines resistance to newer β-lactam/β-lactamase inhibitor combinations among carbapenem-resistant Pseudomonas aeruginosa & highlights important clinical implications for treatment & future research in #AMR🔗duke.is/ARLG-pub-pop-mdro
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