@AIMedEdJC

Journal club for the allergy & immunology community || #AIMedEdJC || All are welcome || Next session TBD

Joined October 2020
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Thanks all who joined in the 2022-23 @AIMedEdJC season! We’re taking a break for the summer and look forward to reuniting soon
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#AIMedEd #AAAAI23
FIT_AAAAI_org@FIT_AAAAI_org21 Feb 2023
It’s time for our annual AAAAI Scavenger Hunt! Be on the lookout for the items in the next tweet while you’re in San Antonio for the AAAAI Annual Meeting:
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Allergy & Immunology Journal Club retweeted
Paneez Khoury, MD (she/her)@KhouryMD11 May 2022
A large group from the @EosinophilSoc including @EosDoc @adklion @TPongdee and others published retrospective data on biologic use in #HES. Covered during the last @AIMedEdJC #AIMedEdJC Covered more here 👇🏾 xitter.cf/KhouryMD/status/151506…
Paneez Khoury, MD (she/her)@KhouryMD15 Apr 2022
📈⬆️ interest in using biologics for patients with eosinophilic disorders One main issue: ‼️ Most not approved or have warnings for #eosinophil associated diseases like HES ✅ Clinical workgroup of the @EosinophilSoc set up multicenter databases to answer some key Qs A 🧵
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Thanks to @DrCorinneHappel for tonight's questions! #AIMedEdJC
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Thanks all who joined in last week's @AIMedEdJC Allergy & Immunology Journal Club! The numbers: 142 Tweets. 17 Participants. 201,366 Impressions. April 28th 2022. More #AIMedEdJC 📊 here symplur.com/healthcare-hasht…
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Thanks @somewheresy for the great teaching point! Eosinophil counts quickly drop (often to zero) after oral/iv corticosteroids. Do NOT use a normal eosinophil count to rule out eosinophilic disease without verifying a person was not on corticosteroids. #AIMedEdJC #MedTwitter
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The effects of corticosteroids can linger for a few weeks. If an eosinophilic disorder is suspected & it is safe to stop corticosteroids, an eosinophil count can be checked again after a few weeks to see if there is an elevated baseline level. #AIMedEd #AIMedEdJC #eosinophil I
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Thanks @JACIInPractice for providing open access to this month's #AIMedEdJC discussion article (link below)! An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes jaci-inpractice.org/article/… @KhouryMD @EosDoc #eosinophil

An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinoph...

Treatment of hypereosinophilic syndrome (HES) often requires the use of immunomodulators with substantial side effect profiles. The emergence of biologics offers an alternative treatment modality.

jaci-inpractice.org
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We encourage asynchronous discussion to continue through Saturday, May 30th! Search the hashtag #AIMedEdJC to find questions posted last night and to jump in the conversation. #eosinophils #allergy #immunology #AIMedEd #biologics
Thanks for bringing this up, @karenrobbinsmd and thanks for the initial post, @winder_gill! Great article to take a look at👇 relevant to this week’s #AIMedEdJC topic
Karen Robbins, MD@karenrobbinsmd29 Apr 2022
Replying to @winder_gill @AIMedEdJC
I think there’s other data out there to support this….am recalling a @ckeet @aolayink article where amongst publicly insured individuals, “White patients accounted for a disproportionate amount of biologic treatment” #AIMedEdJC pubmed.ncbi.nlm.nih.gov/3355…

Lower Use of Biologics for the Treatment of Asthma in Publicly Insured Individuals - PubMed

Biologics were uncommonly used among patients with asthma, and the basis for disproportionately lower use of biologics among the publicly insured, where the burden of uncontrolled asthma is greatest,...

pubmed.ncbi.nlm.nih.gov
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Allergy & Immunology Journal Club retweeted
Peter Olbrich@petolb_huvr29 Apr 2022
Replying to @AIMedEdJC
For the inborn error of immunity part please consider having a look on our recent review #AImedEdJC @JACIInPractice jaci-inpractice.org/article/…
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Allergy & Immunology Journal Club retweeted
Hippocrates@md_hippocrates29 Apr 2022
Replying to @AIMedEdJC
Don’t forget new drugs recently #AIMedEdJC
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Allergy & Immunology Journal Club retweeted
Hippocrates@md_hippocrates29 Apr 2022
Agree and I have had the opposite occur….re check and AeC is markedly elevated #AIMedEdJC
Dan Rosenberg@TitanOfTryptase29 Apr 2022
Replying to @md_hippocrates @PAallergy @AIMedEdJC
Re-check eos is a big one! I've gotten a few consults with only one screen > 1500 and on repeat it was normal. #AIMedEdJC
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Great point @winder_gill! The differential for eosinophilia is huge. Allergist-immunologists are always happy to help but also appreciate if you are also considering non-allergic causes 😀 #AIMedEdJC
Dr. Winder Gill@winder_gill29 Apr 2022
Replying to @AIMedEdJC
I think there is a larger 'takehome' message not just for us, but for #primarycare and those involved with our patients - We often see eosinophilia on labwork, and yes, it can be associated with atopic disorders, but please consider the differentials! #AIMedEdJc @AIMedEdJC
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Do you appreciate @AIMedEdJC journal clubs? Would you like to get involved in the planning process or to lead a future journal club? We welcome fresh energy & ideas! Please reach out to @DrCorinneHappel for more info. #AIMedEdJC
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Save the date: Our next journal club is tentatively scheduled for Thursday, May 26th at 9:00 PM EST. Hope to see you there! #AIMedEdJC
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Particular thanks to author @KhouryMD for joining in tonight's discussion! We really appreciated having your expertise. #AIMedEdJC
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Allergy & Immunology Journal Club retweeted
Paneez Khoury, MD (she/her)@KhouryMD29 Apr 2022
Replying to @shaunah07 @PAallergy @AIMedEdJC
If you can make the eos go down some with skin care...then more likely AD associated eosinophilia. If no matter what you do to the skin eos remain elevated and refractory skin dz then probably other way around. No easy answer but clinical judgement #AIMedEdJC
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As always, thanks so much for joining in tonight's synchronous Twitter-based journal club! We welcome continued asynchronous discussion over the next 48 hours to include those with other schedules & time zones. #AIMedEdJC
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Allergy & Immunology Journal Club retweeted
Hippocrates@md_hippocrates29 Apr 2022
Replying to @AIMedEdJC
Philosophical question: in pt a AD w elevated eos do they have AD w elevated AEC as part of the disease or do they have HES manifesting as AD? #AIMedEdJC
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