Andrew Hildreth (@ADHildreth) header
Andrew Hildreth (@ADHildreth) profile picture

Andrew Hildreth

@ADHildreth

PhD candidate in the O’Sullivan Lab at UCLA. Dendritic cells are the way

 Los Angeles, CA
Joined February 2021
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  • Following65
  • Followers72
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Photo by Andrew Hildreth (@ADHildreth)Photo by Andrew Hildreth (@ADHildreth)
The last piece of my thesis work is finally out! Interested in learning about the roles of cDC1s during obesity-associated inflammation? Check out our story here:
Nature Metabolism (@NatMetabolism) profile pictureNature Metabolism
@NatMetabolism17 Jan 2024
RESEARCH | Andrew Hildreth et al. (@dgsomucla): The authors show that during DIO, conventional type 1 dendritic cells (cDC1s) in WAT take up DNA-containing apoptotic bodies from adipocytes, which contributes to WAT #inflammation in mice. nature.com/articles/s42255-0…
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Super excited to share the first of my thesis work papers! cDC1 are protective during drug-induced acute liver injury! Big thanks to everyone who helped make it happen! #CellReports cell.com/cell-reports/fullte…
Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic...

Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic...

Hildreth et al. identify conventional type 1 dendritic cells (cDC1s) and interleukin (IL)-12 as critical regulators of sterile inflammation during acute liver injury. cDC1-intrinsic cGAS-STING...

cell.com
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Got the chance to share our work on human adipose ILC subsets at #ilc4 and #Cytokines2022 conference on the big island, Hawaii. Big shout out to @OSullivanLab for making this possible!
Image from Andrew Hildreth (@ADHildreth)
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Ken Murphy lab strikes again: “Ablation of cDC2 development by triple mutations within the Zeb2 enhancer” in ⁦@Nature⁩. 👏🏻👏🏻👏🏻👏🏻 For the journal club list 🤩🤩🤩🤩 nature.com/articles/s41586-0…
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer

Ablation of cDC2 development by triple mutations within the Zeb2 enhancer

Nature - The transcription factor NFIL3 acts antagonistically to C/EBP proteins by binding the Zeb2 enhancer to prevent Zeb2 expression and the development of the conventional type 2 dendritic cell...

nature.com
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Andrew Hildreth retweeted
Immunity (@ImmunityCP) profile picture
Immunity@ImmunityCP18 Jun 2022
cDC1 to cDC2: “Everything I do, Ido1 it for you” dlvr.it/SSQsHL
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Been waiting a while for this one! Super interesting study by the Hasty lab in ⁦@NatureComms⁩ interrogating the immune changes that occur during obesity, weight loss, and weight cycling in mice! nature.com/articles/s41467-0…
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Andrew Hildreth retweeted
Dr Becs (@ScientistBecs) profile picture
Dr Becs@ScientistBecs16 May 2022
Replying to @ADHildreth
@ADHildreth from @OSullivanLab presenting his super cool data looking at NK cell-dependent cDC1 recruitment in obesity!! Super cool, calm and collected, hope I can channel that vibe in the next session! #NK2022
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Trying to stay off twitter but this session is just far too good 😵‍💫 @ADHildreth from @OSullivanLab about adipose tissue ILC/NK subsets and one of my favorite topics: NK/DC interactions. Shoutout to two of my fav papers by @CrozatKarine (2021) and @JBoettcherLab (2018) #nk2022
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Beyond thrilled to officially receive my NOA for the NIDDK F31 award! It didn’t quite set in until today. Huge shoutout to @OSullivanLab and @UCLAMBI for giving me the opportunity to make this happen! #F31 #NIDDK
Image from Andrew Hildreth (@ADHildreth)
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Great week in the Covarrubias Lab @MicrobioUcla. We are collaborating with the @OSullivanLab to edit innate immune cells for an exciting collaborative project with the Alex Hoffman Lab studying the role of inflammatory signaling pathways in aging immune cells! UCLA Immunology!
Image from Anthony J. Covarrubias (@ACovarrubiasPhD)
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Andrew Hildreth retweeted
Holly V. Goodson (@HVGoodson) profile picture
Holly V. Goodson@HVGoodson23 Sep 2021
Come join us at Notre Dame! We have two open positions (tenure track, any rank) and are especially enthusiastic to see applications from those specializing in molecular biology, synthetic biology, or biochemistry. Apply at apply.interfolio.com/93452
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Super excited to share our recent work detailing the changes that occur within the human adipose tissue using single-cell RNAseq! Huge thanks to all of our collaborators at UCLA, esp. @OSullivanLab for making this happen!
Nature Immunology (@NatImmunol) profile pictureNature Immunology@NatImmunol27 Apr 2021
O’Sullivan and colleagues generate a comprehensive single-cell atlas of of human white adipose tissue to identify new cell states in health and obesity.rdcu.be/cjw2V
Image from Nature Immunology (@NatImmunol)
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