Enabling next generation medicines.
Brisbane, CA
Joined July 2018
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New product launch: Today we’re launching LV Apex Suite, a new product suite for lentiviral vector production.
This marks 64x Bio’s expansion from AAV into LV — and another step in translating our CellMap-driven VectorSelect platform across new modalities.
LV Apex Suite begins with a high yield engineered HEK293T suspension cell line for transient LV production, with stable systems and additional production-enabling technologies in development.
More broadly, this launch reflects where 64x Bio is headed: expanding CellMap as a data foundation for production biology, and learning from those data computationally to iteratively guide development of better cell lines, reagents, and production systems for viral vectors — and soon, biologics.
To learn more about LV Apex Suite, read our press release below and visit 64xbio.com/lvapexsuite.
Press release: 64xbio.com/articles/64x-bio-…
64x Bio retweeted
@64xbio is moving into lentiviral vector production with LV Apex Suite. Led by @lexrovner, the launch expands 64x Bio’s CellMap-driven VectorSelect platform beyond AAV, targeting productivity and scalability bottlenecks in cell and gene therapy manufacturing.
businesswire.com/news/home/2…
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Thanks @PharmaMfg for covering our LV Apex Suite launch!
To read more about our new product launch, read our press release here: 64xbio.com/articles/64x-bio-…
#64xBio adds #cellengineering platform to #lentiviralvector manufacturing. The new product suite extends the company's vector production platform beyond #AdenoAssociatedVirus applications to support #lentiviral therapies. pharmamanufacturing.com/indu… #AAVs #viralvectors #biologics
We'll be in San Diego next week for #BIO2026! The 64x team will be on the ground and @lexrovner is on two panels on advanced medicines, across AI and manufacturing. If you'll be there, we'd love to meet — reach out to us in the BIO partnering portal or at [email protected]
.@TMenichiello at @BioProcessOL wrote a great summary of our panel at #BIO2025 on biomanufacturing for advanced therapies. Take a look:
bioprocessonline.com/doc/how…
64x Bio retweeted
I joined @iamjulieo, @KateRochlin, and @bruna_paulsen last week at BIO, to talk about biomanufacturing for advanced medicines -- such a critical piece of making this field work. Big thanks to @MadridMarinna for moderating and giving me the opportunity to spotlight the work we've been doing to help tackle these challenges through our platform and new product line, AAV Apex Suite.
Of course, none of this would be possible without the incredible team @64xbio -- they're the ones doing the real heavy lifting.
64x Bio retweeted
At BIO, Companies Launch New Products for AAV Manufacturing, AI Drug Discovery
@64xbio and @faunabio innovators launched products that solve challenges in #genetherapy scale-up and learn from omics data from animals and humans
@IAmBiotech #AAV #AI
hubs.li/Q03t0J5h0
64x Bio retweeted
Great coverage from @UduakThomas9861 at GEN on how our team @64xbio is working hard to build solutions for manufacturing bottlenecks in gene therapy, starting with our new Apex Suite. We had a great (and jet lagged) conversation at BIO in Boston last week:
genengnews.com/topics/biopro…
64x Bio retweeted
AAV Apex Suite made its debut last week. Thanks @SynBioBeta (and George 🙂) for amplifying the message. I’m so proud of our team. @64xbio
64x Bio retweeted
Super fortunate to have @FutureJurvetson in our corner very early on before the dream was a reality! Steve and Maryanna at Future are as good as it gets. Grateful for you both 🙏
And currently on stage, Lexi Rovner, CEO of @64xBio, the most efficient AAV supplier for scaling mammalian cell line manufacturing (we are investors)
64x Bio retweeted
I'm excited for the opportunity to be speaking alongside these great panelists tomorrow. And stay tuned for some exciting news we'll be sharing after SynBioBeta!
Catch 64x Bio at @SynBioBeta in San Jose, this week! Our CEO & co-founder @lexrovner will be speaking on two panels on Wednesday 5/7.
Today we’re announcing AAV Apex Suite, a powerful suite of tools for end-to-end AAV production.
The future of medicine is taking shape, but scaling it remains a challenge. Some of the biggest breakthroughs in gene therapy continue to be held back by manufacturing constraints. Overcoming this barrier will be a key step in moving the field forward.
AAV Apex Suite includes engineered suspension-adapted HEK293 clonal cell lines and robust, transfer-ready processes built around commercially available consumables. Our cell lines have been independently confirmed by partners across multiple scales, serotypes, and therapeutic payloads at high titer and quality.
As an initial demonstration of our VectorSelect platform, AAV Apex cell lines already achieve unconcentrated bioreactor titers over E15 viral genomes per liter.
Read our press release: 64xbio.com/articles/64x-bio-…
Learn more about AAV Apex Suite, our VectorSelect platform, and how to work with us, on our new website at 64xbio.com, developed in collaboration with the talented team at Bunsen!
Catch 64x Bio at @SynBioBeta in San Jose, this week! Our CEO & co-founder @lexrovner will be speaking on two panels on Wednesday 5/7.
64x Bio retweeted
🚀 2 Months Until #SynBioBeta2025!
We’re excited to announce new speakers joining SynBioBeta 2025, the leading synthetic biology conference.
Join us May 5-8, 2025, in San Jose, California, for key industry insights and networking opportunities.
🔗 Register now!
64x Bio retweeted
It’s been an exciting start to #JPM2025 Healthcare Week! 🎉 @CellinoBio began the week in #SanFrancisco at #BiotechShowcase, where our CEO, @nabsicle, spoke at the "Cell & Gene Therapy" workshop. Thank you to everyone who joined—let’s connect during #JPMWeek!
ALT Biotech Showcase 2025 | Cell & Gene Therapy: Moving Beyond Discovery and Into the Patient
64x Bio retweeted
Had a great first day at #JPM25 #BiotechShowcase meeting @nabsicle @CellinoBio @rejuvenatebio @lexrovner @64xbio @RayTherapeutics @DinaRadenkovic @GametoGen @endpts @ArmstrongDrew 🧬🧬
64x Bio retweeted
If you live in SF and want to start a deep tech company, you should come.
If you're in SF for Deep Tech Week, join us this Thursday at our office for a panel discussion with top YC founders!
They'll share stories & advice from the early days of building their own deep tech startups, and going from 0 to 1.
RSVP: yc.link/DeepTechWeek
A nice summary of what 64x is working on from one of our first investors. Thanks @sethbannon @fiftyyears!
Our enthusiasm is a combination of first principles analysis on the likelihood that HEK293 or other existing cell lines that we used to manufacture viral vectors are optimal (very low), with first principles analysis of the 64x approach to finding better cell lines (good), with data they've shown on their ability to find increases in performance through their multiplexed screening (also good).
Over a 10 year time, we're also likely to have much better viral vectors which require less to be manufactured. And I wouldn't be surprised if we also see some breakthroughs and cell-free manufacture of them.
64x Bio retweeted
Congratulations Pamela Silver of @harvardmed, newly inducted #NASmember! #NAS161 #biochemistry #biology
