Scientist, molecular and genetic mechanisms of hypertension, kidney function, father, hubby, musician, music lover, climbing, runner, opinions are my own
Detroit, MI
Joined April 2019
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Pinned Tweet
so proud of this girl!!! First poster at a national meeting, #ASCBEMBO2019 #ASCBEMBO19 @m_mendez_313 @Mottillo_Lab @HFHypertension @uniliggett
POrtiz_313_Kidney retweeted
Trump’s restrictions spark chaos across health and science agencies trib.al/ynfRqNy
POrtiz_313_Kidney retweeted
A Trump freeze on NIH grant review has scientists alarmed, and worried about long-term impacts. Teamed up with @MeganMolteni and a number of @statnews colleagues (@ushamcfarling, @EricBoodman, @angRchen & @AnilOza16) for this story
statnews.com/2025/01/24/trum…
POrtiz_313_Kidney retweeted
Trump blocks NIH review. I’m on a study section to review cancer grants but received this email today:
NIH has paused all communication, as directed by the new administration (e.g. cnn.com/2025/01/21/health/hh… ), and that apparently includes a pause for all study section meetings
POrtiz_313_Kidney retweeted
NEW—Trump WH has blocked all CDC science reports (eg MMWR) & suspended all CDC / FDA / NIH external communications of all HHS agencies until further notice... including all FDA & CDC Health Alert warnings & all social media. Public health be damned.
Gift 🎁 link below.
POrtiz_313_Kidney retweeted
Better AAV Delivery for Kidney Gene Therapy
Gene transfer for kidney disease is challenging. To address this, a team used “context-dependent selection of AAV capsids.”
hubs.li/Q0315QlD0
POrtiz_313_Kidney retweeted
#APSselect study from @AJPRenal suggests that the protein actinin-4 interacts with the Na+/K+/2Cl cotransporter to regulate the kidney’s thick ascending limb salt reabsorption: ow.ly/Kyma50Uk8Jt CC: @AJPRenalEIC, @313Kidney
POrtiz_313_Kidney retweeted
Researchers identify #benzamil as potential treatment for skin #inflammation in #psoriasis mouse and human xenograft skin models. @StanfordMed @UCSFMedicine scim.ag/3BrGtEv
Congrats to Dipak Maskey @dipakraj78 from @HFHypertension @HenryFordHealth on having your new paper selected by @APSPublications . Certainly a novel finding that ACTN4 regulates renal tubular NaCl transport.
Congrats to Dipak Maskey et al. for the #APSselect paper "The FSGS protein actinin-4 (ACTN4) interacts with NKCC2 to regulate Thick Ascending Limb (TAL) NaCl reabsorption." in @AJPRenal
ow.ly/EfeQ50UkY0N
POrtiz_313_Kidney retweeted
This light-sheet microscopy three-dimensional rendering shows a first-of-its-kind mouse whole-brain mRNA analysis at single-cell resolution.
Learn more in this week’s issue: bit.ly/3CCapy5
POrtiz_313_Kidney retweeted
#Hypertension24 was fun! Grateful to have had the opportunity to present our work at the just ended AHA Hypertension Session. Also honored to be a recipient of these awards. Special thanks to my mentor @313Kidney who is a great source of inspiration . @KidneyInCVD @CouncilonHTN
POrtiz_313_Kidney retweeted
A new preclinical study shows that the protein #WNK1—a potential drug target in #cancer and hypertension—also plays important roles in humoral #immunity and #Bcell migration, suggesting scientists should develop WNK1 inhibitors with caution. @NIAIDNews scim.ag/8dS
POrtiz_313_Kidney retweeted
📣📣📣 #KidneyCamp is on!!! 📣📣📣 I repeat, Kidney Camp is back on - Summer 2026!!! 🤩🫘☀️Thanks to @APSPhysiology !! Stay tuned for more details! @clintoria @jenpluznick @DrKeeksPhD @KidneyInCVD @staruschenko @313Kidney please spread the news! 🤩
POrtiz_313_Kidney retweeted
Spread the word- The Epithelial Transport Group has a new Twitter/X handle! Follow us for updates regarding new research, upcoming conferences, and career development!
An outstanding APS summit in 2024 ! #wearephysiology @HFHypertension #APS2024 congrats to all trainees and postdocs who received or competed for awards , we return with lots of ideas and new collaborations @CardiorenalRese @petitejessy
POrtiz_313_Kidney retweeted
Congratulations to Data Diuresis winner Isaac Baiden, MD for giving a fantastic talk on “Loop Diuretic Resistance In A Mouse Model of Cardiorenal” @APSPhysiology #APS2024!
POrtiz_313_Kidney retweeted
Nearly half of U.S. adults have high blood pressure — but only a quarter of those with hypertension have it under control, according to the CDC.
Here's why high blood pressure matters, and how to to lower it. nyti.ms/3P1TtEi
POrtiz_313_Kidney retweeted
"Proximal tubule transport is suppressed under conditions of high dietary [potassium] intake. This could contribute to the maintenance of both [potassium] and [sodium] balance ...." Read more in @AJPRenal #ArticlesInPresS: ow.ly/tQKX50OTQJw CC: @AJPRenalEIC
POrtiz_313_Kidney retweeted
Single-cell analyses in humans and mice have revealed the identity of the kidney's erythropoietin-producing cells — opening up new avenues of research for anemia and related disorders.
News and Views from @KSusztak & colleagues @PennMedicine
nature.com/articles/s41591-0…